Results 261 to 270 of about 73,331 (301)

Evaluation of new apolipoprotein C-II and apolipoprotein C-III automatized immunoturbidimetric kits

Clinical Biochemistry, 2006
Apolipoprotein C-II and apolipoprotein C-III play an important and complex role in plasma triglycerides metabolism, respectively, as inhibitor and activator of lipoprotein lipase. Thus, they appear to be suitable markers for clinical studies of triglyceride-rich lipoproteins and related cardiovascular risk. Our aim was to evaluate, for routine analysis,
Nicolay, Alain, Lombard, Elise, Arlotto, Emmanuelle, Saunier, Vincent, Lorec-Penet, Anne-Marie, Lairon, Denis, Portugal, Henri   +6 more
openaire   +4 more sources

Apolipoprotein C-II deficiency. The role of apolipoprotein C-II in the hydrolysis of triacylglycerol-rich lipoproteins.

Biochimica et biophysica acta, 1984
Kinetic studies were performed incubating lipoprotein lipase and hepatic triacylglycerol lipase from human postheparin plasma with triacylglycerol-rich lipoproteins from two patients with apolipoprotein C-II deficiency. These lipoproteins differed in their lipid and apolipoprotein composition from normal very-low-density lipoproteins and chylomicrons ...
W, Haberbosch, A, Poli, G, Baggio, R, Fellin, A, Gnasso, J, Augustin   +5 more
openaire   +1 more source

Apolipoprotein and lipoprotein concentrations in familial apolipoprotein C-II deficiency.

Atherosclerosis, 1982
Lipoprotein and apolipoprotein concentrations were determined in 11 homozygous and 9 heterozygous subjects for familial apolipoprotein C-II (Apo C-II) deficiency. Apo C-II was not detectable in the homozygotes, with the exception of 1 subject who possessed immunochemically detectable quantities in one of two samples.
W C, Breckenridge, P, Alaupovic, D W, Cox, J A, Little   +3 more
openaire   +1 more source

Immunochemistry of human plasma apolipoprotein C-II as studied by radioimmunoassay

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1981
The immunoreactivity of human plasma apolipoprotein C-II was investigated using a specific radioimmunoassay. In whole plasma, the mean value quantitated was 2.21 +/- 0.415 mg/dl, while in delipidated plasma, a mean value of 3.84 +/- 1.186 mg/dl was obtained, suggesting that the antigenic sites of the apolipoprotein were not fully detected in unmodified
S I, Barr, B A, Kottke, J Y, Chang, S J, Mao   +3 more
openaire   +2 more sources

[Apolipoprotein C-II deficiency].

Nihon rinsho. Japanese journal of clinical medicine, 1995
Apo C-II has a central role in triglyceride metabolism as a cofactor for lipoprotein lipase (LPL), the enzyme that catalyzes the hydrolysis of triglycerides on plasma lipoproteins. Apo C-II deficiency is a rare genetic disorder that is inherited as an autosomal recessive trait.
openaire   +1 more source

A Rapid Radioimmunoassay of Human Apolipoproteins C-Ii and C-Iii

Scandinavian Journal of Clinical and Laboratory Investigation, 1984
Apolipoprotein (apo) C-II is an activator of lipoprotein lipase, while apo C-III has the ability to inhibit apo C-II activated lipolysis. In order to study further the relationship between lipoprotein lipase mediated hydrolysis and the serum concentrations of apo C-II and apo C-III we have developed radioimmunoassays for these apolipoproteins. Apo C-II
S, Gustafson, A M, Ostlund-Lindqvist, B, Vessby   +2 more
openaire   +2 more sources

Apolipoprotein C-II-Defizienz im Säuglingsalter

2011
Eineitung: Apolipoprotein C-II-Defizienz ist eine sehr seltene autosomal-rezessiv vererbbare Stoffwechselerkrankung, die durch extrem erhöhte Serumkonzentrationen von Triglyceriden (bis 30.000 mg/dl) sowie Chylomikronen (milchig-rahmiges Serum) gekennzeichnet ist. Das Apo C-II-Gen liegt auf[for full text, please go to the a.m. URL]
Lauerer, P, Steinmetz, M, Paul, T, Brockmann, K, Seeliger, S   +4 more
openaire   +1 more source

Apolipoprotein C-II Tuzla: A novel large deletion in APOC2 caused by Alu-Alu homologous recombination in an infant with apolipoprotein C-II deficiency

Clinica Chimica Acta, 2015
Familial apolipoprotein (apo) C-II deficiency is a very rare inherited disorder characterized by chylomicronemia. Since the discovery in 1978, reports on apo C-II deficient patients have been limited and only 13 different mutations in APOC2, a gene encoding apo C-II protein, were identified.The objective is to investigate the biochemical and genetic ...
Minoru, Okubo, Alma, Toromanovic, Tetsu, Ebara, Toshio, Murase   +3 more
openaire   +2 more sources

Genetic studies of human apolipoproteins. III. Polymorphism of apolipoprotein C-II.

Human heredity, 1988
Using a simple and rapid one-dimensional isoelectric focusing technique followed by immunoblotting, we have detected genetic polymorphism of human apolipoprotein C-II (APO C-II) in normal unfractionated plasma samples of individuals of black ancestry. Two common autosomal codominantly expressed alleles, designated APO C-II*1 and APO C-II*2, at the APO ...
B, Sepehrnia, M I, Kamboh, R E, Ferrell
openaire   +1 more source

Apolipoprotein C-II deficiency

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1984
W. Haberbosch, A. Poli, G. Baggio, R. Fellin, A. Gnasso, J. Augustin   +5 more
openaire   +1 more source