Results 211 to 220 of about 20,685,408 (374)
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley +1 more source
A Robust Serum Proteomic Signature of the E2 Allele of Apolipoprotein E. [PDF]
Sebastiani P +20 more
europepmc +1 more source
The influence of the apolipoprotein-E polymorphism in the lipid profile of Alzheimer's disease or vascular dementia patients [PDF]
Silvia Aparecida Soares
openalex +1 more source
CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li +8 more
wiley +1 more source
Neutralizing hepatic apolipoprotein E enhances aged bone fracture healing. [PDF]
Huang M +4 more
europepmc +1 more source
Methodological problems in genetic association studies of longevity--the apolipoprotein E gene as an example [PDF]
Sarah J. Lewis
openalex +1 more source
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang +22 more
wiley +1 more source
Uncovering the Complexity of Synucleinopathies: An Ongoing Tale Between Proteins and Lipids
Abstract Neurodegenerative diseases are pathological states characterized by progressive alterations in brain homeostasis during aging. Synucleinopathies, including Parkinson's disease and dementia with Lewy bodies, are defined neuropathologically by the accumulation of inclusions known as Lewy bodies and Lewy neurites.
Manuel Flores‐León, Tiago F. Outeiro
wiley +1 more source

