Results 231 to 240 of about 121,670 (308)

Mex‐3 RNA‐binding family member A limits macrophage ferroptosis‐associated injury linked to the SLC7A11/GPX4 pathway in diabetic atherosclerosis

open access: yesClinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Diabetes reduces macrophage MEX3A and aggravates atherosclerotic plaque instability. MEX3A stabilises Slc7a11 and Gpx4 mRNAs to sustain SLC7A11/GPX4 antioxidant defence. MEX3A deficiency promotes macrophage ferroptosis, lipid peroxidation and mitochondrial injury. Ferrostatin‐1 partially attenuates ferroptotic injury and diabetic plaque destabilisation.
Yanpeng Ma   +7 more
wiley   +1 more source

Advances in the Study of Endometrial Receptivity and Glucose Metabolism Mechanisms in Insulin Resistance

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
This article systematically reviews how insulin resistance (IR) disrupts endometrial receptivity by interfering with glucose metabolism mechanisms, ultimately leading to infertility in patients with Polycystic Ovary Syndrome (PCOS). ABSTRACT Introduction Insulin resistance (IR) is one of the important pathologic bases of polycystic ovary syndrome (PCOS)
Si‐yan Huang   +7 more
wiley   +1 more source

Relationship Between Central Sensitization and Genetic Polymorphisms—A Case–Control Study in Fibromyalgia

open access: yesEuropean Journal of Pain, Volume 30, Issue 6, July 2026.
ABSTRACT Background Fibromyalgia is a syndrome characterised by widespread chronic pain, which is believed to be mediated by a state of central sensitisation (CS). Based on the hypothesis that CS itself could have genetic determinants, our aim was to further explore this pathway.
Nicolas Macian   +8 more
wiley   +1 more source

Therapeutic Potential of Berberis vulgaris in Modulating Metabolic Syndrome Biomarkers: Mechanistic Insights and Functional Food Implications

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Barberry (Berberis vulgaris) has emerged as a promising functional food candidate for the management of metabolic syndrome due to its diverse bioactive constituents, particularly berberine. This review synthesizes current experimental and clinical evidence regarding its effects on glycemic control, lipid metabolism, blood pressure regulation ...
Fakhar Shahid   +5 more
wiley   +1 more source

Apolipoprotein E and presenilin-1 genotypes in Huntington's disease

open access: yes, 1999
Panas, M   +4 more
core  

Apolipoprotein E Mimetic Peptide CN-105 and Postoperative Delirium in Older Patients: The Phase 2 MARBLE Randomized Clinical Trial.

open access: yesJAMA Netw Open
Timko NJ   +27 more
europepmc   +1 more source

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