Apolipoprotein E and alzheimer's disease: Ethnic variation in genotypic risks
, 1995 Gladys E. Maestre +8 more
openalex +2 more sources
Cyclodextrin‐Based Pseudocopolymers and Their Biomedical Applications for Drug and Gene Delivery
Small, EarlyView.Host–guest interactions between cyclodextrin (CD) and compatible guest molecules enable the formation of diverse architectures, such as multiblock and linear–star copolymers as well as advanced systems like redox‐responsive nanoparticles. This structural versatility facilitates precise system design, conferring multifunctionality for controlled drug ...
Wilson Wee Mia Soh, Jun Li
wiley +1 more source
Clinical efficacy of anti-amyloid antibodies in apolipoprotein E ε4 homozygotes: A Bayesian reanalysis of lecanemab and donanemab phase 3 results. [PDF]
Alzheimers Dement (N Y)Teipel S, Tang Y, Khachaturian A.
europepmc +1 more source
Small, EarlyView.This work presents a proof‐of‐concept digital microfluidic device that can automatedly extract EVs from microliters of biological and physiological fluids within 25 min and detect EV‐bound protein markers on‐chip using electrochemical sensor. This work serves as a framework for the development of streamlined EV analysis in both medicine research and ...
Ting‐Wen Lo +7 more
wiley +1 more source
Retraction: Apolipoprotein E-mimetic peptide COG1410 promotes autophagy by phosphorylating GSK-3β in early brain injury following experimental subarachnoid hemorrhage. [PDF]
Front NeurosciFrontiers Editorial Office.
europepmc +1 more source
Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons
Small Science, EarlyView.This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong +4 more
wiley +1 more source
Two rodent suborders have evolved missing amino acids in the lipid-binding region of apolipoprotein E. [PDF]
LipidsPuppione DL.
europepmc +1 more source
Therapeutic Implications of Biomolecular Corona on Lipid Nanoparticle‐Based Gene Delivery Systems
Small Science, EarlyView.This image illustrates the role of the biomolecular corona in lipid nanoparticles (LNPs), highlighting its impact on the stability, immune response, biodistribution, and targeted delivery. Formed after injection, the corona influences how LNPs circulate, interact with the cells, and modulate the immune response.
Antonietta Greco, Claudia Corbo
wiley +1 more source