Results 31 to 40 of about 20,685,408 (374)
Apolipoprotein E Protects against NMDA Excitotoxicity
Neurobiology of Disease, 2002 Preclinical and clinical evidence implicates a role for endogenous apolipoprotein E in modifying the response of the brain to focal and global ischemia.
Mitsuo Aono +7 more
doaj +1 more source
African Journal of Laboratory Medicine, 2023 Background: Dyslipidaemia is a known cause of cardiovascular mortality. Persons living with HIV are at high risk of developing cardiovascular disease due to lipid metabolism disorders associated with HIV or its therapy.
Mercy N. Okunorobo +3 more
doaj +1 more source
Neuropsychiatric Disease and Treatment, 2022 Gupta AK, Pokhriyal R, Das U, et al. Neuropsychiatr Dis Treat. 2019;15:2073–2085. The authors wish to advise of typographical errors in Figures 1 and 2 and Table 3, the correct unit of apolipoprotein E concentration is μg/ml, and not pg/ml. Page
Gupta AK +10 more
doaj
C2238/αANP modulates apolipoprotein E through Egr-1/miR199a in vascular smooth muscle cells in vitro [PDF]
, 2015 Subjects carrying the T2238C ANP gene variant have a higher risk to suffer a stroke or myocardial infarction. The mechanisms through which T2238C/αANP exerts detrimental vascular effects need to be fully clarified.
Bianchi, Franca +9 more
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Association of APOE gene polymorphism with stroke patients from rural Eastern India
Annals of Indian Academy of Neurology, 2020 Context: Studies from the different ethnic regions of the world have reported variable results on association of APOE gene polymorphism in stroke. Aim: The aim of this study is to find out the possible association of APOE polymorphism in stroke patients ...
Hilal Ahmad Ganaie +5 more
doaj +1 more source
Apolipoprotein E and Atherosclerosis: From Lipoprotein Metabolism to MicroRNA Control of Inflammation. [PDF]
, 2018 Apolipoprotein (apo) E stands out among plasma apolipoproteins through its unprecedented ability to protect against atherosclerosis. Although best recognized for its ability to mediate plasma lipoprotein clearance in the liver and protect against ...
Hasty +6 more
core +2 more sources
Apolipoprotein E and Alzheimer's Disease [PDF]
Annual Review of Neuroscience, 1995 The apolipoprotein E locus (APOE) is associated with variations in the age of onset and risk of Alzheimer's disease. The APOE4 allele increases the probability of disease at an earlier age. In contrasL the APOE3 and APOE2 alleles decrease the probability of disease and increase the age of onset. Therefore the metabolism of apolipoprotein E is relevant
W J, Strittmatter, A D, Roses
openaire +3 more sources
The Carboxyl-Terminal Segment of Apolipoprotein A-V Undergoes a Lipid-Induced Conformational Change [PDF]
, 2010 Apolipoprotein (apo) A-V is a 343-residue, multidomain protein that plays an important role in regulation of plasma triglyceride homeostasis. Primary sequence analysis revealed a unique tetraproline sequence (Pro293-Pro296) near the carboxyl terminus of ...
Lee, B. L. +4 more
core +2 more sources
Association of Apolipoprotein E ε4 With Medial Temporal Tau Independent of Amyloid-β.
JAMA Neurology, 2019 Importance Apolipoprotein E ε4 (APOEε4) is the single most important genetic risk factor for Alzheimer disease. While APOEε4 is associated with increased amyloid-β burden, its association with cerebral tau pathology has been controversial. Objective To
J. Therriault +18 more
semanticscholar +1 more source
Functional significance of polymorphism of ApoE and SOD2 genes in formation of chronic HCV infection
Бюллетень сибирской медицины, 2009 The analysis of gene polymorphism plays an important role in assessment of disposition to infectious diseases at the population and individual level. In this paper, the frequencies of allelic versions of apolipoprotein E and 2nd type superoxide dismutase
N. A. Semyonova +6 more
doaj +1 more source