The Carboxyl-Terminal Segment of Apolipoprotein A-V Undergoes a Lipid-Induced Conformational Change [PDF]
, 2010 Apolipoprotein (apo) A-V is a 343-residue, multidomain protein that plays an important role in regulation of plasma triglyceride homeostasis. Primary sequence analysis revealed a unique tetraproline sequence (Pro293-Pro296) near the carboxyl terminus of ...
Lee, B. L. +4 more
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Functional significance of polymorphism of ApoE and SOD2 genes in formation of chronic HCV infection
Бюллетень сибирской медицины, 2009 The analysis of gene polymorphism plays an important role in assessment of disposition to infectious diseases at the population and individual level. In this paper, the frequencies of allelic versions of apolipoprotein E and 2nd type superoxide dismutase
N. A. Semyonova +6 more
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Apolipoprotein E polymorphism in a Romanian population
Romanian Journal of Cardiology, 2023 Background: Apolipoprotein E (ApoE) is a ubiquitous protein involved in maintaining cholesterol homeostasis and lipoprotein clearance from circulation. It is coded by three alleles (ε2, ε3, ε4) with six genotypes (ε3/ε3, ε3/ε4, ε2/ε3, ε4/ε4, ε2/ε4, and ...
Diaconu Rodica +8 more
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Estimating the level of carbamoylated plasma non-high-density lipoproteins using infrared spectroscopy [PDF]
, 2019 Background: The increased cardiovascular morbidity and mortality observed in chronic kidney disease (CKD) patients can be partly explained by the presence of carbamoylated lipoproteins. Lipid profiles can be determined with infrared spectroscopy. In this
De Baene, Linde +5 more
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Clinical and Experimental Hypertension, 2021 Objective This study aimed to analyze the influence of SLCO1B1 and APOE gene polymorphisms on coronary heart disease in Mongolian population who living in Ordos area.
Rui-Bing Niu +6 more
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IgG anti-apolipoprotein A-1 antibodies in patients with systemic lupus erythematosus are associated with disease activity and corticosteroid therapy: an observational study. [PDF]
, 2015 IgG anti-apolipoprotein A-1 (IgG anti-apoA-1) antibodies are present in patients with systemic lupus erythematosus (SLE) and may link inflammatory disease activity and the increased risk of developing atherosclerosis and cardiovascular disease (CVD) in ...
Alber, KF +9 more
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Herpes Simplex Virus Type 1 in the Brain, Apolipoprotein E Genotype and Alzheimer’s Disease
McGill Journal of Medicine, 2020 The ε4 allele of apolipoprotein E (apoE) is an important risk factor for Alzheimer's disease (AD), however, it is not required nor sufficient to cause the disease on its own.
Uwe Beffert +4 more
doaj +1 more source
Familial dysbetalipoproteinemia: highly atherogenic and underdiagnosed disorder
Кардиоваскулярная терапия и профилактика, 2021 Familial dysbetalipoproteinemia (FD) is a genetic, highly atherogenic disorder. The penetrance of FD depends on the patient’s lifestyle and concomitant diseases. Despite the fact that FD was described almost half a century ago, it is still insufficiently
A. V. Blokhina +3 more
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Probable Early-Onset Alzheimer's Disease in an Apolipoprotein E2 Homozygote [PDF]
, 2010 Objective: To describe a case of early-onset Alzheimer's disease (AD) in an apolipoprotein (Apo) epsilon 2/epsilon 2 homozygote. Background: Apo epsilon 2/epsilon 2 is the rarest of the ApoE genotypes, representing only 1.4% of the population.
Belden, Christine +7 more
core +2 more sources
Association of APOE gene polymorphism with stroke patients from rural Eastern India
Annals of Indian Academy of Neurology, 2020 Context: Studies from the different ethnic regions of the world have reported variable results on association of APOE gene polymorphism in stroke. Aim: The aim of this study is to find out the possible association of APOE polymorphism in stroke patients ...
Hilal Ahmad Ganaie +5 more
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