Results 11 to 20 of about 196,159 (307)
Apolipoprotein E related Co-Morbidities and Alzheimer’s disease [PDF]
, 2016 The primary goal of advancement in clinical services is to provide a health care system that enhances an individual’s quality of life. Incidence of diabetes mellitus, cardiovascular disease and associated dementia coupled with the advancing age of the ...
Akiyama +147 more
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Neurobiology of Disease, 1997 Apolipoprotein E has been shown to be a risk factor for late-onset Alzheimer's disease, with the apolipoprotein ϵ4 allele conferring the risk. Apolipoprotein E is found in neurofibrillary tangles and senile plaques, the pathological characteristics of ...
Kieran R. Williams +4 more
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Relationship between Apolipoprotein Superfamily and Parkinson's Disease
Chinese Medical Journal, 2017 Objective: Parkinson's disease (PD) is featured with motor disorder and nonmotor manifestations including psychological symptoms, autonomic nervous system dysfunction, and paresthesia, which results in great inconvenience to the patients' life.
Lin Li +8 more
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Apolipoprotein Mimetic Peptides: A New Approach for the Treatment of Asthma
Frontiers in Pharmacology, 2012 New treatments are needed for severe asthmatics to improve disease control and avoid severe toxicities associated with oral corticosteroids. We have used a murine model of house dust mite (HDM)-induced asthma to identify steroid-unresponsive genes that ...
Xianglan eYao +3 more
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Apolipoprotein E Interferes with IAPP Aggregation and Protects Pericytes from IAPP-Induced Toxicity
Biomolecules, 2020 Apolipoprotein E (ApoE) has become a primary focus of research after the discovery of its strong linkage to Alzheimer’s disease (AD), where the ApoE4 variant is the highest genetic risk factor for this disease.
Anna L. Gharibyan +9 more
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Apolipoprotein E and Atherosclerosis: From Lipoprotein Metabolism to MicroRNA Control of Inflammation. [PDF]
, 2018 Apolipoprotein (apo) E stands out among plasma apolipoproteins through its unprecedented ability to protect against atherosclerosis. Although best recognized for its ability to mediate plasma lipoprotein clearance in the liver and protect against ...
Hasty +6 more
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Indian Journal of Dermatology, 2023 Background: Apolipoprotein E (APOE) gene isoforms have been found to affect the risk of superficial fungal infections (SFIs). However, the data only cover a few ethnicities.
Amany I Mustafa +5 more
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Images in cardiovascular medicine : multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery [PDF]
, 2007 Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventitia is a major site of arterial wall inflammation associated with lymphocyte infiltration into atherosclerotic arteries and with formation of adventitial ...
Baker, Andrew H. +7 more
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Apolipoprotein E and Alzheimer's Disease [PDF]
Annual Review of Neuroscience, 1995 The apolipoprotein E locus (APOE) is associated with variations in the age of onset and risk of Alzheimer's disease. The APOE4 allele increases the probability of disease at an earlier age. In contrasL the APOE3 and APOE2 alleles decrease the probability of disease and increase the age of onset. Therefore the metabolism of apolipoprotein E is relevant
W J, Strittmatter, A D, Roses
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Apolipoprotein E gene polymorphisms as risk factors for carotid atherosclerosis [PDF]
Vojnosanitetski Pregled, 2014 Background/Aim. Atherosclerosis is still the leading cause of death in Western world. Development of atherosclerotic plaque involves accumulation of inflammatory cells, lipids, smooth muscle cells and extracellular matrix proteins in the intima ...
Zurnić Irena +5 more
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