Results 11 to 20 of about 121,670 (308)

Apolipoprotein E ε4 is superior to apolipoprotein E ε2 in predicting cognitive scores over 30 months

Clinical Interventions in Aging, 2013
Paul Regal, Balakrishnan Nair, Eileen Hetherington Geriatric Medicine and Gerontology, University of Newcastle, Callaghan, NSW, Australia Background: The purpose of this study was to compare apolipoprotein E ε4 (Apo E ε4) and ...
Regal P, Nair B, Hetherington E
doaj   +1 more source

E2/E3 and E3/E4 Genotypes of the Apolipoprotein E are Associated with Higher Risk of Diabetes Mellitus in Patients with Hypertension

International Journal of General Medicine, 2023
Wendao Han,1,2 Nating Xiong,1,2 Renkai Zhong,1,2 Zhongyi Pan1,2 1Department of Blood Transfusion, Meizhou People’s Hospital, Meizhou Academy of Medical Sciences, Meizhou, People’s Republic of China; 2Center for Precision Medicine, Meizhou People’s ...
Han W, Xiong N, Zhong R, Pan Z
doaj   +1 more source

Apolipoprotein E polymorphism and neuropsychological outcome following subarachnoid haemorrhage [PDF]

, 2004
Objectives–To investigate the association between APOE genotype and cognitive and emotional outcome following spontaneous subarachnoid haemorrhage (SAH).Materials and methods–Neuropsychological assessments were conducted with 70 SAH survivors derived ...
Morris, Paul Graham; id_orcid, Nicoll, James A R, Dunn, L.T., Wilson, J T Lindsay, Dunn, Laurence T, Nicoll, J.A., Wilson, J.T., Morris, P.G.   +7 more
core   +1 more source

Apolipoprotein E Uptake and Low-Density Lipoprotein Receptor-Related Protein Expression by the NTera2/D1 Cell Line: A Cell Culture Model of Relevance for Late-Onset Alzheimer's Disease

Neurobiology of Disease, 1997
Apolipoprotein E has been shown to be a risk factor for late-onset Alzheimer's disease, with the apolipoprotein ϵ4 allele conferring the risk. Apolipoprotein E is found in neurofibrillary tangles and senile plaques, the pathological characteristics of ...
Kieran R. Williams, Victoria Pye, Ann M. Saunders, Allen D. Roses, Patricia J. Armati   +4 more
doaj   +1 more source

Relationship between Apolipoprotein Superfamily and Parkinson's Disease

Chinese Medical Journal, 2017
Objective: Parkinson's disease (PD) is featured with motor disorder and nonmotor manifestations including psychological symptoms, autonomic nervous system dysfunction, and paresthesia, which results in great inconvenience to the patients' life.
Lin Li, Ming-Su Liu, Guang-Qin Li, Jie Tang, Yan Liao, Yang Zheng, Tong-Li Guo, Xin Kang, Mao-Ting Yuan   +8 more
doaj   +1 more source

Apolipoprotein AIV gene variant S347 is associated with increased risk of coronary heart disease and lower plasma apolipoprotein AIV levels [PDF]

, 2003
The impact of common variants in the apolipoprotein gene cluster (APOC3-A4-A5) on prospective coronary heart disease (CHD) risk was examined in healthy UK men. Of the 2808 men followed over 9 years, 187 had a clinically defined CHD event.
Hawe, E., Miller, G.J., Hawe, Emma, Nicaud, V., Wong, W.-M.R., Wong, Wai-man R., Humphries, S.E., Li, Lai K., Li, L.K., Talmud, P.J., Nicaud, Viviane, Miller, George J., Pennacchio, Len A., Talmud, Philippa J., Pennacchio, L.A., Humphries, Steve E.   +15 more
core   +1 more source

Apolipoprotein Mimetic Peptides: A New Approach for the Treatment of Asthma

Frontiers in Pharmacology, 2012
New treatments are needed for severe asthmatics to improve disease control and avoid severe toxicities associated with oral corticosteroids. We have used a murine model of house dust mite (HDM)-induced asthma to identify steroid-unresponsive genes that ...
Xianglan eYao, Michael P. Vitek, Alan T. Remaley, Stewart J. Levine   +3 more
doaj   +1 more source

Apolipoprotein E gene polymorphism, serum lipids, and risk of superficial fungal infections in Egyptian patients – A preliminary case-controlled study

Indian Journal of Dermatology, 2023
Background: Apolipoprotein E (APOE) gene isoforms have been found to affect the risk of superficial fungal infections (SFIs). However, the data only cover a few ethnicities.
Amany I Mustafa, Ghada M Shams, Eman M Fawzy, Naglaa F Alhusseini, Rana A Khashaba, Ola S EL-Shimi   +5 more
doaj   +1 more source

Apolipoprotein E gene polymorphisms as risk factors for carotid atherosclerosis [PDF]

Vojnosanitetski Pregled, 2014
Background/Aim. Atherosclerosis is still the leading cause of death in Western world. Development of atherosclerotic plaque involves accumulation of inflammatory cells, lipids, smooth muscle cells and extracellular matrix proteins in the intima ...
Zurnić Irena, Đurić Tamara, Končar Igor, Stanković Aleksandra, Dinčić Dragan, Živković Maja   +5 more
doaj   +1 more source

Apolipoprotein E Protects against NMDA Excitotoxicity

Neurobiology of Disease, 2002
Preclinical and clinical evidence implicates a role for endogenous apolipoprotein E in modifying the response of the brain to focal and global ischemia.
Mitsuo Aono, Yoonki Lee, Elfrida R. Grant, Robert A. Zivin, Robert D. Pearlstein, David S. Warner, Ellen R. Bennett, Daniel T. Laskowitz   +7 more
doaj   +1 more source