Results 31 to 40 of about 121,670 (308)

Study on the relationship between SLCO1B1 and ApoE gene polymorphisms and the risk of coronary heart disease in the Mongolian population

Clinical and Experimental Hypertension, 2021
Objective This study aimed to analyze the influence of SLCO1B1 and APOE gene polymorphisms on coronary heart disease in Mongolian population who living in Ordos area.
Rui-Bing Niu, Xiao-Xian Dong, Li-Ping Guo, Li Pan, Yue-Qin Hai, Xiao-Xiao Chen, Bao-Sheng Duan   +6 more
doaj   +1 more source

IgG anti-apolipoprotein A-1 antibodies in patients with systemic lupus erythematosus are associated with disease activity and corticosteroid therapy: an observational study. [PDF]

, 2015
IgG anti-apolipoprotein A-1 (IgG anti-apoA-1) antibodies are present in patients with systemic lupus erythematosus (SLE) and may link inflammatory disease activity and the increased risk of developing atherosclerosis and cardiovascular disease (CVD) in ...
Davari, M, Yiannis Ioannou, Isenberg, D, Paul Bassett, Rahman, A, David Isenberg, Anisur Rahman, Maria Davari, Alber, KF, Ioannou, Y, Oliver Leach, Giles, I, Bassett, P, Karim Alber, Ian Giles, Leach, O, Sara Croca, Chambers, S, Croca, S, Sharon Chambers   +19 more
core   +1 more source

Apolipoprotein E polymorphism in a Romanian population

Romanian Journal of Cardiology, 2023
Background: Apolipoprotein E (ApoE) is a ubiquitous protein involved in maintaining cholesterol homeostasis and lipoprotein clearance from circulation. It is coded by three alleles (ε2, ε3, ε4) with six genotypes (ε3/ε3, ε3/ε4, ε2/ε3, ε4/ε4, ε2/ε4, and ...
Diaconu Rodica, Dumitrașcu Andreea-Ramona, Liehn Elisa, Pîrvu Andrei, Ioana Mihai, Alexandru Dragoș, Țieranu Eugen, Bălșeanu Tudor-Adrian, Donoiu Ionuț   +8 more
doaj   +1 more source

Images in cardiovascular medicine : multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery

, 2007
Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventitia is a major site of arterial wall inflammation associated with lymphocyte infiltration into atherosclerotic arteries and with formation of adventitial ...
McInnes, I.B., ZINSELMEYER BH, Zinselmeyer, B.H., Ialenti, Armando, Brewer, James M., Brewer, J.M., Maffia, P., BREWER JM, Ialenti, A., MCINNES IB, Kennedy, S., Baker, Andrew H., Baker, A.H., McInnes, Iain B., Zinselmeyer, Bernd H., Garside, P., KENNEDY S, Maffia, Pasquale, Kennedy, Simon, GARSIDE P., Garside, Paul, BAKER AH, McInnes, I.   +22 more
core   +1 more source

Apolipoprotein E expression in aortic smooth muscle cells: the effect of beta VLDL.

Journal of Lipid Research, 1994
The expression of apolipoprotein E in cultured neonatal rabbit aortic smooth muscle cells was examined. Northern blot analysis determined that there was a single RNA transcript of approximately 1.2 kb.
B M Schreiber, H V Jones, C Franzblau
doaj   +1 more source

Apolipoprotein E gene polymorphisms: a relationship with the risk of coronary artery disease and the effectiveness of lipid-lowering therapy with rosuvastatin

Кардиоваскулярная терапия и профилактика, 2020
Aim. To analyze the associations of apolipoprotein E (APOE) gene polymorphisms (rs7412 and rs4420638) with the risk of coronary artery disease (CAD) and the effectiveness of lipid-lowering therapy with rosuvastatin.Material and methods.
M. I. Churilin, S. I. Kononov, Yu. V. Luneva, Yu. E. Azarova, E. Yu. Klesova, A. V. Kharchenko, S. N. Zhabin, O. Yu. Bushueva, S. V. Povetkin, G. S. Mal, M. A. Solodilova, A. V. Polonikov, V. A. Kazanov   +12 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Apolipoprotein E Gene Polymorphism and Coronary Artery Disease Risk Among Patients in Northwest China

Pharmacogenomics and Personalized Medicine, 2021
Wenbing Ma,1,2 Xiaodong Ren,1 Liting Zhang,1 Haiyan Dong,1 Xiaoyun Lu,2 Weiyi Feng1 1Department of Pharmacology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, 710061, People’s Republic of China; 2Department of Biological ...
Ma W, Ren X, Zhang L, Dong H, Lu X, Feng W   +5 more
doaj  

Familial dysbetalipoproteinemia: highly atherogenic and underdiagnosed disorder

Кардиоваскулярная терапия и профилактика, 2021
Familial dysbetalipoproteinemia (FD) is a genetic, highly atherogenic disorder. The penetrance of FD depends on the patient’s lifestyle and concomitant diseases. Despite the fact that FD was described almost half a century ago, it is still insufficiently
A. V. Blokhina, A. I. Ershova, A. N. Meshkov, O. M. Drapkina   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source