Results 31 to 40 of about 196,159 (307)

Association of APOE gene polymorphism with stroke patients from rural Eastern India

open access: yesAnnals of Indian Academy of Neurology, 2020
Context: Studies from the different ethnic regions of the world have reported variable results on association of APOE gene polymorphism in stroke. Aim: The aim of this study is to find out the possible association of APOE polymorphism in stroke patients ...
Hilal Ahmad Ganaie   +5 more
doaj   +1 more source

The N-Terminus of Apolipoprotein A-V Adopts a Helix-Bundle Molecular Architecture [PDF]

open access: yes, 2008
Previous studies of recombinant full-length human apolipoprotein A-V (apoA-V) provided evidence of the presence of two independently folded structural domains.
Beckstead, J. A.   +6 more
core   +3 more sources

Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila [PDF]

open access: yes, 2008
Apolipoprotein D (ApoD) expression increases in several neurological disorders and in spinal cord injury. We provide a report of a physiological role for human ApoD (hApoD): Flies overexpressing hApoD are long-lived and protected against stress ...
Ahn   +30 more
core   +3 more sources

Apolipoprotein £ and Epilepsy [PDF]

open access: yesAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1996
The overall frequencies of the apolipoprotein f2, f3 and f4 alleles in the epilepsy patients were no different to those of the control group (Table 1). Subgroups consisting of patients with either an unknown aetiology for epilepsy (71% of patients), a family history of epilepsy (21% of patients), idiopathic generalized epilepsy, or cryptogenic partial ...
E S, Kilpatrick   +3 more
openaire   +2 more sources

Herpes Simplex Virus Type 1 in the Brain, Apolipoprotein E Genotype and Alzheimer’s Disease

open access: yesMcGill Journal of Medicine, 2020
The ε4 allele of apolipoprotein E (apoE) is an important risk factor for Alzheimer's disease (AD), however, it is not required nor sufficient to cause the disease on its own.
Uwe Beffert   +4 more
doaj   +1 more source

Study on the relationship between SLCO1B1 and ApoE gene polymorphisms and the risk of coronary heart disease in the Mongolian population

open access: yesClinical and Experimental Hypertension, 2021
Objective This study aimed to analyze the influence of SLCO1B1 and APOE gene polymorphisms on coronary heart disease in Mongolian population who living in Ordos area.
Rui-Bing Niu   +6 more
doaj   +1 more source

A well-characterised peak identification list of MALDI MS profile peaks for human blood serum [PDF]

open access: yes, 2010
MALDI MS profiling, using easily available body fluids such as blood serum, has attracted considerable interest for its potential in clinical applications.
Anderson   +22 more
core   +1 more source

Apolipoprotein E polymorphism in a Romanian population

open access: yesRomanian Journal of Cardiology, 2023
Background: Apolipoprotein E (ApoE) is a ubiquitous protein involved in maintaining cholesterol homeostasis and lipoprotein clearance from circulation. It is coded by three alleles (ε2, ε3, ε4) with six genotypes (ε3/ε3, ε3/ε4, ε2/ε3, ε4/ε4, ε2/ε4, and ...
Diaconu Rodica   +8 more
doaj   +1 more source

Apolipoprotein E gene polymorphisms: a relationship with the risk of coronary artery disease and the effectiveness of lipid-lowering therapy with rosuvastatin

open access: yesКардиоваскулярная терапия и профилактика, 2020
Aim. To analyze the associations of apolipoprotein E (APOE) gene polymorphisms (rs7412 and rs4420638) with the risk of coronary artery disease (CAD) and the effectiveness of lipid-lowering therapy with rosuvastatin.Material and methods.
M. I. Churilin   +12 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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