Results 111 to 120 of about 37,488 (288)

Transcription‐Replication Conflicts: Unlocking New Frontiers in Cancer

BioEssays, EarlyView.
Transcription‐replication conflicts (TRCs) constitute a major source of genome instability. Such conflicts are regulated by chromatin, its dysfunction causing replication stress, DNA breaks, and mutations frequently found in cancer. We review the molecular basis of TRCs and chromatin regulation and discuss the clinical potential of targeting TRCs as ...
Aleix Bayona‐Feliu, Andrés Aguilera
wiley   +1 more source

Distribution of apolipoproteins A-I and B among intestinal lipoproteins.

Journal of Lipid Research, 1985
Chylomicrons and very low density lipoproteins (VLDL) are produced by the intestine and these nascent particles are thought to be similar to their counterparts in intestinal lymph.
D H Alpers, D R Lock, N Lancaster, K Poksay, G Schonfeld   +4 more
doaj  

Phosphatidylcholine and its relation to apolipoproteins A-1 and B changes after Roux-en-Y gastric bypass: a cohort study

Lipids in Health and Disease, 2019
Background Phosphatidylcholine (PC), the most abundant of the phospholipids, has several metabolic functions in organs such as the liver and the intestine, important structural- and signaling functions in biological membranes, and might have a role in ...
Elin Rebecka Carlsson, Kristine H. Allin, Sten Madsbad, Mogens Fenger   +3 more
doaj   +1 more source

Serotonergic Modulators in Alzheimer's Disease: A Hope in the Hopeless Condition

Chemistry &Biodiversity, EarlyView.
ABSTRACT Alzheimer's disease (AD) is the main cause of dementia worldwide. AD is a progressive brain neurodegenerative disease due to genetic and environmental factors that induce a progressive accumulation of intracellular hyperphosphorylated tau protein and extracellular amyloid protein (Aβ).
Najlaa Hamed Almohmadi, Hayder M. Al‐Kuraishy, Ali I. Al‐Gareeb, Ali K. Albuhadily, Morkoss M. Fakhry, Athanasios Alexiou, Marios Papadakis, Gaber El‐Saber Batiha   +7 more
wiley   +1 more source

Utility of apolipoprotein measurements in predicting incident type 2 diabetes: A Chinese cohort study

Journal of the Formosan Medical Association, 2020
Background/purpose: There is conflicting data regarding the utility of measuring apolipoproteins in addition to traditional lipid measures in risk assessment of cardiometabolic diseases.
Yu-Ching Chou, San-Lin You, Chyi-Huey Bai, Yu-Chan Liao, Cheng-Yu Wei, Chien-An Sun   +5 more
doaj  

Coronary Plaque Characteristics Assessed by Optical Coherence Tomography and Plasma Lipoprotein(a) Levels in Patients With Acute Coronary Syndrome

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Lipoprotein(a) [Lp(a)] is associated with increased cardiovascular risk, but its influence on plaque characteristics at optical coherence tomography (OCT) evaluation is not fully understood. Aims This study seeks to explore the impact of Lp(a) levels on plaque morphology as assessed by OCT in a very high‐risk subset of patients ...
Francesca Maria Di Muro, Maria Federica Crociani, Giulia Nardi, Niccolo' Ciardetti, Lucrezia Biagiotti, Elisa Bigi, Francesco Meucci, Miroslava Stolcova, Francesca Ristalli, Emanuele Cecchi, Iacopo Muraca, Renato Valenti, Carlo Di Mario, Alessio Mattesini   +13 more
wiley   +1 more source

Apolipoproteins of HDL can directly mediate binding to the scavenger receptor SR-BI, an HDL receptor that mediates selective lipid uptake

Journal of Lipid Research, 1997
The class B type I scavenger receptor, SR-BI, binds HDL, mediates selective uptake of HDL cholesteryl esters by cultured cells, and its expression is coordinately regulated with steroidogenesis in several endocrine tissues (adrenal, ovary, testes). SR-BI
S Xu, M Laccotripe, X Huang, A Rigotti, V I Zannis, M Krieger   +5 more
doaj  

Metabolic heterogeneity of apolipoprotein B in the rat

Journal of Lipid Research, 1981
Triglyceride-rich lipoprotein apoprotein catabolism was studied in rats from 5 to 60 min after intravenous injection of 125I-labeled lipoproteins. The plasma and liver labeled apoprotein content was analyzed by gel filtration column chromatography using an elution buffer containing 1% sodium dodecyl sulfate.
Julian B. Marsh, Charles E. Sparks
openaire   +4 more sources

PCSK‐9 Inhibitors Can Significantly Improve the Coronary Slow Flow Caused by Elevated Lipoprotein (a) in ST‐Elevation Myocardial Infarction Patients With Chronic Kidney Disease

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary slow flow and no reflow significantly predict poor prognosis in acute myocardial infarction (AMI) patients, especially those with chronic kidney disease (CKD). Early identification of factors contributing to these conditions can mitigate ischemic events and improve outcomes.
Hao Xu, Ziqing Wang, Dan Chen, Haojie Zhang, Junhua Ge, Jian Li   +5 more
wiley   +1 more source

Increased production of apolipoprotein B and its lipoproteins by oleic acid in Caco-2 cells.

Journal of Lipid Research, 1990
The production of lipids, apolipoproteins (apo), and lipoproteins induced by oleic acid has been examined in Caco-2 cells. The rates of accumulation in the control medium of 15-day-old Caco-2 cells of triglycerides, unesterified cholesterol, and ...
N Dashti, EA Smith, P Alaupovic
doaj