Results 111 to 120 of about 12,961,080 (334)

Vitamin B12 Levels Association with Functional and Structural Biomarkers of Central Nervous System Injury in Older Adults

Annals of Neurology, EarlyView.
At low levels of B12, specifically when bound to transcobalamin for cellular uptake, evidence of slower conductivity in the brain could point toward impaired myelin. At high levels of B12, specifically when bound to the biologically inert transport protein haptocorrin, biomarkers of neurodegeneration appear in the serum, indicating neuroaxonal injury ...
Alexandra Beaudry‐Richard, Ahmed Abdelhak, Rowan Saloner, Simone Sacco, Shivany C. Montes, Frederike C. Oertel, Christian Cordano, Nour Jabassini, Kirtana Ananth, Apraham Gomez, Azeen Keihani, Makenna Chapman, Sree Javvadi, Shikha Saha, Adam Staffaroni, Christopher Songster, Martin Warren, John W. Boscardin, Joel Kramer, Bruce Miller, Joshua W. Miller, Ralph Green, Ari J. Green   +22 more
wiley   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Utility of apolipoprotein measurements in predicting incident type 2 diabetes: A Chinese cohort study

Journal of the Formosan Medical Association, 2020
Background/purpose: There is conflicting data regarding the utility of measuring apolipoproteins in addition to traditional lipid measures in risk assessment of cardiometabolic diseases.
Yu-Ching Chou, San-Lin You, Chyi-Huey Bai, Yu-Chan Liao, Cheng-Yu Wei, Chien-An Sun   +5 more
doaj  

Phosphatidylcholine and its relation to apolipoproteins A-1 and B changes after Roux-en-Y gastric bypass: a cohort study

Lipids in Health and Disease, 2019
Background Phosphatidylcholine (PC), the most abundant of the phospholipids, has several metabolic functions in organs such as the liver and the intestine, important structural- and signaling functions in biological membranes, and might have a role in ...
Elin Rebecka Carlsson, Kristine H. Allin, Sten Madsbad, Mogens Fenger   +3 more
doaj   +1 more source

Neuropathological Evidence of Reduced Amyloid Beta and Neurofibrillary Tangles in Multiple Sclerosis Cortex

Annals of Neurology, EarlyView.
Multiple sclerosis (MS) and Alzheimer's disease are neurodegenerative diseases with age‐related disability accumulation. In MS, inflammation spans decades, whereas AD is characterized by Aβ plaques and neurofibrillary tangles (NFT). Few studies explore accumulation of amyloids in MS.
J. Pansieri, M. Pisa, S. Yee, A. Gutnikova, E. Ridgeon, R. Hickman, J.I. Spencer, M.M. Esiri, G.C. DeLuca   +8 more
wiley   +1 more source

Apolipoproteins of HDL can directly mediate binding to the scavenger receptor SR-BI, an HDL receptor that mediates selective lipid uptake

Journal of Lipid Research, 1997
The class B type I scavenger receptor, SR-BI, binds HDL, mediates selective uptake of HDL cholesteryl esters by cultured cells, and its expression is coordinately regulated with steroidogenesis in several endocrine tissues (adrenal, ovary, testes). SR-BI
S Xu, M Laccotripe, X Huang, A Rigotti, V I Zannis, M Krieger   +5 more
doaj  

Metabolic heterogeneity of apolipoprotein B in the rat

Journal of Lipid Research, 1981
Triglyceride-rich lipoprotein apoprotein catabolism was studied in rats from 5 to 60 min after intravenous injection of 125I-labeled lipoproteins. The plasma and liver labeled apoprotein content was analyzed by gel filtration column chromatography using an elution buffer containing 1% sodium dodecyl sulfate.
Julian B. Marsh, Charles E. Sparks
openaire   +4 more sources

Role of STING Deficiency in Amelioration of Mouse Models of Lupus and Atherosclerosis

Arthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) is a systemic autoimmune syndrome characterized by autoreactive responses to nucleic acids, dysregulation of the type I interferon (IFN‐I) pathway, and accelerated atherosclerosis. The stimulator of IFN genes (STING), a cytosolic DNA sensor, has pathogenic implications in various inflammatory diseases ...
Yudong Liu, Carmelo Carmona‐Rivera, Nickie L. Seto, Christopher B. Oliveira, Eduardo Patino‐Martinez, Yvonne Baumer, Tiffany M. Powell‐Wiley, Nehal Mehta, Sarfaraz Hasni, Xuan Zhang, Mariana J. Kaplan   +10 more
wiley   +1 more source

Increased production of apolipoprotein B and its lipoproteins by oleic acid in Caco-2 cells.

Journal of Lipid Research, 1990
The production of lipids, apolipoproteins (apo), and lipoproteins induced by oleic acid has been examined in Caco-2 cells. The rates of accumulation in the control medium of 15-day-old Caco-2 cells of triglycerides, unesterified cholesterol, and ...
N Dashti, EA Smith, P Alaupovic
doaj  

Apolipoproteins B and A1 in Ischemic Stroke Subtypes. [PDF]

J Stroke Cerebrovasc Dis, 2020
Kalani R, Krishnamoorthy S, Deepa D, Gopala S, Prabhakaran D, Tirschwell D, Sylaja PN.   +6 more
europepmc   +1 more source