Results 121 to 130 of about 12,469,641 (375)

Apolipoprotein A‐V Regulation of Apolipoprotein B Secretion

The FASEB Journal, 2006
Apolipoprotein ( APO ) A5 is a recently discovered member of the APOA1/C3/A4 gene cluster. Studies with APOA5 transgenic and gene disrupted mice showed that apoA‐V is a key regulator of plasma ...
Xiao Shu, Trudy Forte, Robert O. Ryan
openaire   +1 more source

Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen, Xu Zhang, Rui Fan, Xia Li, Feifei Guan, Gefan Wan, Weining Kong, Xiaolong Qi, Shuo Pan, Sijing Shi, Yuanlong Su, Shan Gao, Wei Huang, Xunde Xian, Jiangning Liu, Yuhui Wang, Yuanwu Ma   +16 more
wiley   +1 more source

Chronic high‐fat diet induces multi‐organ dysfunction and metabolic homeostasis disruption in Macaca fascicularis

Animal Models and Experimental Medicine, EarlyView.
An 18‐month HFD successfully established a translational Macaca fascicularis model replicating key metabolic disorders (MASH, diabetes, cardiac hypertrophy). MASH was determined by liver biopsy histology, the presence steatosis, inflammatory infiltration, hepatocytic ballooning, and fibrosis were considered as MASH; diabetes was diagnosed according to ...
Hongyi Chen, Wei Liu, Dan Zhou, Shuhua Liu, Yalun Guan, Zongyu Miao, Lei Cai, Xuejiao Li, Yunfeng Li, Zhongqiang Huang, Yi Jin, Ge Li, Yu Zhang   +12 more
wiley   +1 more source

Determination of apolipoproteins B-48 and B-100 in triglyceride-rich lipoproteins by analytical SDS-PAGE.

Journal of Lipid Research, 1994
The present work describes a procedure for determining apolipoproteins (apo) B-100 and B-48 in subfractions of triglyceride-rich lipoproteins by analytical sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) with Coomassie staining.
F Karpe, A Hamsten
doaj   +1 more source

Establishment of a mouse model of TMAO‐induced cardiac injury and application of MICT intervention

Animal Models and Experimental Medicine, EarlyView.
This study aims to explore the establishment of an animal model of cardiac injury induced by trimethylamine‐N‐oxide (TMAO), a metabolite secreted by gut microorganisms, and to investigate its application in moderate‐intensity continuous training (MICT) intervention.
Zhongping Xie, Hong Zou, Lijing Gong, Minghui Lin, Caihua Huang   +4 more
wiley   +1 more source

RFLPs for the human apolipoprotein B gene: HincII and PvuII [PDF]

, 1986
Catarina Darnfors, J. Nilsson, Andrew A. Protter, Peter Carlsson, Philippa J. Talmud, Steve E. Humphries, J. Whalström, Olov Wiklund, Gunnar Bjursell   +8 more
openalex   +1 more source

The complexity of dementia development and its comorbidities: The collaborative cross‐mouse population for multivarious tasks approach

Animal Models and Experimental Medicine, EarlyView.
The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud, Iqbal M. Lone, Kareem Midlej, Fuad A. Iraqi   +3 more
wiley   +1 more source

Apolipoproteins B and A1 in Ischemic Stroke Subtypes. [PDF]

J Stroke Cerebrovasc Dis, 2020
Kalani R, Krishnamoorthy S, Deepa D, Gopala S, Prabhakaran D, Tirschwell D, Sylaja PN.   +6 more
europepmc   +1 more source

Effect of estradiol administration and subsequent nonfeeding on liver estrogen receptor, serum apolipoprotein B-100, and serum triglycerides concentrations in steers [PDF]

, 1993
Norio Katoh, Seijiro Minoura, Eiji Uchida, Kiyoshi Takahashi   +3 more
openalex   +1 more source

Informetrics on accidents and trauma [PDF]

, 1998
MEDLINE database has been analysed for 1995-97 on index Accidents and Trauma. Publications output has been classified year-wise country-wise, journal-wise and other fine structure characteristics have been found.
Kadam, S. N., Kalyane, V. L.
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