Results 151 to 160 of about 12,961,080 (334)

Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics

Clinical Pharmacology &Therapeutics, EarlyView.
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou, Rohit Rao, Monica E. Shapiro, Nessy Tania, Cody Herron, Cynthia J. Musante, Jim H. Hughes   +6 more
wiley   +1 more source

Concentrations of Lipids and Apolipoprotein B in Plasma and Lipoprotein Density Classes from Japanese Umbilical Cord Blood

, 1979
Toshitaka TAMAI, Tsuguhiko NAKAI, Shiro YAMADA, Takeshi Kobayashi, Takio YAYASHI, Hasunori KUTSUMI, Ryoyu Takeda   +6 more
openalex   +2 more sources

Lipoprotein metabolism in the ovariectomized rat.

Journal of Lipid Research, 1983
The hyperlipoproteinemia observed after ovariectomy in rats was previously shown to be associated with increased concentrations of cholesterol, triglycerides, and apolipoproteins B, E, and C.
B J van Lenten, G W Melchior, P S Roheim
doaj  

Rabbit and rat C-reactive proteins bind apolipoprotein B-containing lipoproteins. [PDF]

, 1984
I F Rowe, A.K. Soutar, I. Trayner, M L Baltz, Frederick C. de Beer, Lucy S. K. Walker, David E. Bowyer, J. Herbert, A. Feinstein, Mark B. Pepys   +9 more
openalex   +1 more source

Apolipoprotein B deficiency [PDF]

Endocrine Abstracts, 2016
Quiros Juan Manuel Garcia de, Maria Victoria Cozar Leon, Eyvee Arturo Cuellar Lloclla, Alvaro Romero Porcel, Pinillos Guillermo Martinez de, Mariana Tome Fernandez Ladreda, Ignacio Fernandez Lopez, Ignacio Fernandez Pena, Fernando Garcia Perez   +8 more
openaire   +2 more sources

RFLP for the human apolipoprotein B gene: V;Xhal

, 1985
L. Priestley, Timothy J. Knott, S. Wallis, Lynn M. Powell, Richard J. Pease, H. Brunt, James Scott   +6 more
openalex   +2 more sources

Both apolipoproteins B-48 and B-100 are synthesized and secreted by the human intestine

Journal of Lipid Research, 1990
Apolipoprotein B (apoB), an apolipoprotein associated with very low density lipoproteins and the atherogenic low density lipoproteins (LDL), directs the metabolism of lipoprotein particles in plasma by interacting with the LDL receptor.
JM Hoeg, DD Sviridov, GE Tennyson, SJ Demosky, Jr, MS Meng, D Bojanovski, IG Safonova, VS Repin, MB Kuberger, VN Smirnov   +9 more
doaj  

Thyroid hormone and hepatic synthesis of apolipoprotein B

, 1989
Arthur M. Magun
openalex   +1 more source

High-mannose structure of apolipoprotein-B from low-density lipoproteins of human plasma [PDF]

, 1985
Matti Vauhkonen, Juha Viitala, Jaakko Parkkinen, Heikki Rauvala   +3 more
openalex   +1 more source

Genetic factors controlling structure and expression of apolipoproteins B and E in mice.

Journal of Biological Chemistry, 1987
A. J. Lusis, B. Taylor, D. Quon, S. Zollman, R. Leboeuf   +4 more
semanticscholar   +1 more source