Results 11 to 20 of about 12,961,080 (334)

Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh, Rachel S. Kasper, Jessie Sanford, Chia‐Ling Phuah, Jason Hassenstab, Carlos Cruchaga   +5 more
wiley   +1 more source

Diagnostic and pathogenetic significance of apolipoprotein disorders in patients with alcoholic fatty liver [PDF]

Vojnosanitetski Pregled, 2017
Background/Aim. Alcohol is the most common cause of fatty liver. Alcohol metabolism takes place in the liver by alcohol dehydrogenase, to toxic acetaldehyde, with fatty acids accumulation in the liver as a consequence.
Mladenović Bojan, Brzački Vesna, Benedeto-Stojanov Daniela, Mladenović Nikola   +3 more
doaj   +1 more source

Metabolism of apolipoproteins B-48 and B-100 of triglyceride-rich lipoproteins in patients with familial dysbetalipoproteinemia.

Journal of Clinical Investigation, 1986
The metabolism of apolipoproteins B-48 and B-100 (apo B-48 and B-100) in large triglyceride-rich lipoproteins was studied in three adults with familial dysbetalipoproteinemia (F. dys.) and compared to that of normolipidemic subjects. One Caucasian F. dys.
A. Stalenhoef, M. Malloy, J. Kane, R. Havel   +3 more
semanticscholar   +1 more source

Glycosaminoglycans and Apolipoproteins B and A‐l in Human Aortas: Chemical and Immunological Analysis of Lesion‐Free Aortas from Children and Adults

Arteriosclerosis, 1987
To study changes In the contents of plasma llpoprotelns In human arteries with age and the relationship of llpoprotelns with other arterial constituents, we analyzed the contents of apolipoproteins B (apo B) and A-I (apo A-I), free and esterifled ...
S. Ylä-Herttuala, T. Solakivi, Jonma Hirvonen, H. Laaksonen, Matti M6tt6nen, E. Pesonen, J. Raekallio, H. Akerblom, T. Nikkari   +8 more
semanticscholar   +1 more source

Smoking and apolipoprotein levels: A meta-analysis of published data

Toxicology Reports, 2022
Background: Apolipoproteins are major components of lipoproteins such as high-density lipoprotein (HDL) and very-low-density lipoprotein and are considered nontraditional markers in the risk assessment for cardiovascular disease.
Alba Romero Kauss, Meagan Antunes, Guillaume de La Bourdonnaye, Sandrine Pouly, Matthew Hankins, Annie Heremans, Angela van der Plas   +6 more
doaj  

Degradation of human apolipoprotein B‐100 by apolipoprotein(a)

FEBS Letters, 1993
Human plasma low density lipoproteine (LDL) contain a very high molecular weight protein termed apoB‐100 (M r = 550,000). In many samples of LDL, minor components designated as apoB‐74 (M r = 407,000) and apoB‐26 (M r = 145,000) are present. It has been shown that they can arise as a result of proteolytic degradation of apoB‐100.
V.V. Tertov, T.M. Chulkova
openaire   +3 more sources

Apolipoprotein B Is Associated With the Microenvironment of Cholangiocarcinoma [PDF]

Frontiers in Oncology, 2021
BackgroundCholangiocarcinoma (CCA) is a kind of devastating malignancy, which is correlated with the extremely high mortality. Due to the occult pathogenesis of CCA, most patients are diagnosed in the advanced stage. However, the efficacy of chemotherapy and immunotherapy is limited for these patients.
Xiaofeng Xu, Diyu Chen, Diyu Chen, Xiaode Feng, Xiaode Feng, Jiating Hu, Jiating Hu, Jiangzhen Ge, Jiangzhen Ge, Chaobiao Yan, Chaobiao Yan, Deguo Zhang, Deguo Zhang, Zhenan Ling, Zhenan Ling, Jianzhong Chen, Jian Wu, Jian Wu   +17 more
openaire   +3 more sources

Dietary cholesterol does not affect the synthesis of apolipoproteins B and E by rat hepatocytes.

Biochemical Journal, 1985
To examine the unproved hypothesis that dietary cholesterol affects the synthesis of apolipoprotein B and E, we fed rats a cholesterol-rich diet that has been shown to alter dramatically the serum concentrations of these apolipoproteins.
R. Davis, M. Malone-McNeal
semanticscholar   +1 more source

Apolipoprotein[a] is not associated with apolipoprotein B in human liver

Journal of Lipid Research, 1994
The aim of this research was to determine whether apolipoprotein[a] (apo[a]) is linked to apolipoprotein B (apoB) in human liver. Four ELISAs were developed: 1) a competition assay that measures apoB; 2) a competition assay that measures apo[a]; 3) a capture assay based on capture of apo[a] by a polyclonal antibody and detection of co-immobilized apoB ...
Lisa H. Munro, Jane Wilkinson, Joan A. Higgins   +2 more
openaire   +3 more sources

VLDL, Apolipoproteins B, CIII, and E, and Risk of Recurrent Coronary Events in the Cholesterol and Recurrent Events (CARE) Trial

Circulation, 2000
BackgroundPlasma triglyceride concentration has been an inconsistent independent risk factor for coronary heart disease, perhaps because of the metabolic heterogeneity among VLDL particles, the main carriers of triglycerides in plasma.
F. Sacks, P. Alaupovic, L. Moye, T. Cole, B. Sussex, M. Stampfer, M. Pfeffer, E. Braunwald   +7 more
semanticscholar   +1 more source