Hepatitis C virus relies on lipoproteins for its life cycle [PDF]
Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino+5 more
core +1 more source
Peripheral blood mitochondrial DNA content in relation to circulating metabolites and inflammatory markers: a population study [PDF]
Mitochondrial DNA (mtDNA) content might undergo significant changes caused by metabolic derangements, oxidative stress and inflammation that lead to development and progression of cardiovascular diseases.
Brguljan-Hitij, Jana+13 more
core +1 more source
Smoking and apolipoprotein levels: A meta-analysis of published data
Background: Apolipoproteins are major components of lipoproteins such as high-density lipoprotein (HDL) and very-low-density lipoprotein and are considered nontraditional markers in the risk assessment for cardiovascular disease.
Alba Romero Kauss+6 more
doaj
The Carboxyl-Terminal Segment of Apolipoprotein A-V Undergoes a Lipid-Induced Conformational Change [PDF]
Apolipoprotein (apo) A-V is a 343-residue, multidomain protein that plays an important role in regulation of plasma triglyceride homeostasis. Primary sequence analysis revealed a unique tetraproline sequence (Pro293-Pro296) near the carboxyl terminus of ...
Lee, B. L.+4 more
core +2 more sources
Diagnostic and pathogenetic significance of apolipoprotein disorders in patients with alcoholic fatty liver [PDF]
Background/Aim. Alcohol is the most common cause of fatty liver. Alcohol metabolism takes place in the liver by alcohol dehydrogenase, to toxic acetaldehyde, with fatty acids accumulation in the liver as a consequence.
Mladenović Bojan+3 more
doaj +1 more source
Influence of different fat emulsions with 10 or 20% MCT/LCT or LCT on lipoproteins in plasma of patients after abdominal surgery [PDF]
In patients after elective abdominal surgery, different fat emulsions were used to compare their efficacy in total parenteral nutrition and in normalizing plasma lipoprotein levels.
Hailer, Susanne+2 more
core +1 more source
Degradation of human apolipoprotein B‐100 by apolipoprotein(a)
Human plasma low density lipoproteine (LDL) contain a very high molecular weight protein termed apoB‐100 (M r = 550,000). In many samples of LDL, minor components designated as apoB‐74 (M r = 407,000) and apoB‐26 (M r = 145,000) are present. It has been shown that they can arise as a result of proteolytic degradation of apoB‐100.
V.V. Tertov, T.M. Chulkova
openaire +3 more sources
Apolipoprotein B Is Associated With the Microenvironment of Cholangiocarcinoma [PDF]
BackgroundCholangiocarcinoma (CCA) is a kind of devastating malignancy, which is correlated with the extremely high mortality. Due to the occult pathogenesis of CCA, most patients are diagnosed in the advanced stage. However, the efficacy of chemotherapy and immunotherapy is limited for these patients.
Xiaofeng Xu+17 more
openaire +3 more sources
Clinical role of apolipoproteins A and B
The assessment and correction of the traditional parameters of atherogenic dyslipidemia are important, but not exclusive methods in the management of atherosclerosis, including coronary artery atherosclerosis.
G. A. Chumakova+4 more
doaj +1 more source
Apolipoprotein[a] is not associated with apolipoprotein B in human liver
The aim of this research was to determine whether apolipoprotein[a] (apo[a]) is linked to apolipoprotein B (apoB) in human liver. Four ELISAs were developed: 1) a competition assay that measures apoB; 2) a competition assay that measures apo[a]; 3) a capture assay based on capture of apo[a] by a polyclonal antibody and detection of co-immobilized apoB ...
Lisa H. Munro+2 more
openaire +3 more sources