Results 191 to 200 of about 37,488 (288)

Exploring 2D Graphene‐Based Nanomaterials for Biomedical Applications: A Theoretical Modeling Perspective

Small Science, EarlyView.
Two‐dimensional graphene‐based nanomaterials are of significant interest in biomedical applications due to their unique physicochemical properties. Computational modeling provides useful insights into their structure and interactions with biological systems, aiding the nanoparticle design.
Alexa Kamboukos, Nevena Todorova, Irene Yarovsky   +2 more
wiley   +1 more source

Oxidised Apolipoprotein Peptidome Characterises Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]

Liver Int
Mocciaro G, George AL, Allison M, Frontini M, Huang-Doran I, Reiman F, Gribble F, Griffin JL, Vidal-Puig A, Azzu V, Kay R, Vacca M.   +11 more
europepmc   +1 more source

Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons

Small Science, EarlyView.
This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong, Yanyi Peng, Lingyue Zhang, Bo Xiao, Mengqi Zhang   +4 more
wiley   +1 more source

Apolipoprotein-A1 transports and regulates MMP2 in the blood. [PDF]

Nat Commun
Sarker H, Panigrahi R, Lopez-Campistrous A, McMullen T, Reyes K, Anderson E, Krishnan V, Hernandez-Anzaldo S, Zheng XL, Glover JNM, Hardy E, Fernandez-Patron C.   +11 more
europepmc   +1 more source

Systemic Brain Delivery of Oligonucleotide Therapeutics Enhanced by Protein Corona‐Assisted DNA Cubes

Small Methods, EarlyView.
In vivo, screening of DNA nanostructures yields a cube‐shaped structure (D‐Cb) as a protein corona‐assisted platform for brain delivery of oligonucleotide therapeutics. D‐Cb effectively delivers polo‐like kinase 1 (PLK‐1) antisense oligonucleotides (ASO) to treat glioblastoma in an orthotopic mouse model, demonstrating its potential as a carrier for ...
Kyoung‐Ran Kim, Ji Hee Kang, Hien Bao Dieu Thai, Ji Hyun Back, Chengde Mao, Ji Eun Lee, Young Tag Ko, Dae‐Ro Ahn   +7 more
wiley   +1 more source

Validation of the role of apolipoproteins in coronary artery disease patients with impaired kidney function for prognosis: a prospective cohort study in China. [PDF]

Nutr J
Ye Z, Xie E, Lin Z, Song C, Zhang R, Wang H, Zhang Y, Dou K.   +7 more
europepmc   +1 more source

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

The Impact of Cannabidiol (CBD) on Lipid Absorption and Lymphatic Transport in Rats. [PDF]

Nutrients
Zhu Q, Yang Q, Shen L, Xu M, Liu M.
europepmc   +1 more source

Dissecting the genetic architecture of lipids, lipoproteins and apolipoproteins, Lessons from twin studies [PDF]

, 1999
Boomsma, D.I., Doornen, L.J.P. van, Snieder, H.   +2 more
core   +2 more sources

Exosome‐Based Theranostic for Gastrointestinal Cancer: Advances in Biomarker Discovery and Therapeutic Engineering

Small Methods, EarlyView.
This review explores the dual roles of exosomes in gastrointestinal (GI) cancers as diagnostic biomarkers and therapeutic agents. It highlights advancements in exosomal miRNAs, lncRNAs, circRNAs, and proteins for cancer detection and prognosis. The study also examines engineering strategies for exosome‐based drug delivery systems, their potential to ...
Mohit J. Mehta, Dongjun Shin, Hyun Sung Park, Jun Su An, Seong Il Lim, Hyun Jin Kim, Seungpyo Hong, Jiyoon Bu   +7 more
wiley   +1 more source