Results 191 to 200 of about 13,229,252 (212)
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Diagnosis and treatment of apolipoprotein B dyslipoproteinemias
Nature Reviews Endocrinology, 2010Conventionally, atherogenic dyslipidemias have been defined by elevated levels of triglyceride and/or LDL cholesterol. However, cholesterol and triglycerides are not metabolically and physically independent entities. Rather, they are constituents of the atherogenic apolipoprotein B (apoB) particles, which differ in their origin and their metabolic ...
Sniderman, A., Couture, P., Graaf, J. de
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Apolipoproteins A‐I and B in Obese Children
Journal of Pediatric Gastroenterology and Nutrition, 1989Body mass index (BMI), the distribution of fat, birth weight, physical fitness, apolipoproteins (apo) A‐I and B, total cholesterol (TC), and high‐density lipoprotein cholesterol (HDLC) were studied in 38 obese 10− to 11‐year‐olds in comparison to 52 age‐matched controls.
Göran Fex +3 more
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Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1991
A sequential immunoaffinity chromatography procedure was developed to isolate from whole normolipidemic human plasma a subpopulation of apoB containing particles (Lp-B) which is virtually free of non apoB protein. The absence of non apoB protein in Lp-B was assessed by enzyme immunoassay against apolipoproteins A-I, A-II, A-IV, E, C-III and (a ...
Armin Steinmetz +6 more
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A sequential immunoaffinity chromatography procedure was developed to isolate from whole normolipidemic human plasma a subpopulation of apoB containing particles (Lp-B) which is virtually free of non apoB protein. The absence of non apoB protein in Lp-B was assessed by enzyme immunoassay against apolipoproteins A-I, A-II, A-IV, E, C-III and (a ...
Armin Steinmetz +6 more
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1986
ApoE* is a glycoprotein of 299 amino acids which is associated primarily with VLDL and HDL in human plasma (1,2). It is a polymorphic protein with three common alleles inherited in a co-dominant fashion (3,4), the most common allele coding for apoE3. Homozygosity for this allele is present in approximately 60% of normal subjects, and this is considered
Richard E. Gregg, H. Bryan Brewer
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ApoE* is a glycoprotein of 299 amino acids which is associated primarily with VLDL and HDL in human plasma (1,2). It is a polymorphic protein with three common alleles inherited in a co-dominant fashion (3,4), the most common allele coding for apoE3. Homozygosity for this allele is present in approximately 60% of normal subjects, and this is considered
Richard E. Gregg, H. Bryan Brewer
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Atherosclerosis, 2002
Both defective LDL receptors (familial hypercholesterolaemia, FH) and mutations in apolipoprotein B (apoB) on LDL (familial defective apoB, FDB) give rise to a phenotype of elevated LDL cholesterol. We sought to compare the metabolic basis of the two conditions by examining apoB turnover in FDB and FH subjects. A group comprising three heterozygous and
Christopher J. Packard +9 more
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Both defective LDL receptors (familial hypercholesterolaemia, FH) and mutations in apolipoprotein B (apoB) on LDL (familial defective apoB, FDB) give rise to a phenotype of elevated LDL cholesterol. We sought to compare the metabolic basis of the two conditions by examining apoB turnover in FDB and FH subjects. A group comprising three heterozygous and
Christopher J. Packard +9 more
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Metabolism, 2003
Plasma apolipoprotein AIV (apo AIV) level has been shown to be a good marker of triglyceride changes after a high-fat diet. However, the distribution of apo AIV between apo B- and non-apo B-containing lipoproteins (Lp) during the postprandial state has not been described as well as the influence of obesity on this distribution. Our aim was to study the
Jean-Marie Bard +4 more
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Plasma apolipoprotein AIV (apo AIV) level has been shown to be a good marker of triglyceride changes after a high-fat diet. However, the distribution of apo AIV between apo B- and non-apo B-containing lipoproteins (Lp) during the postprandial state has not been described as well as the influence of obesity on this distribution. Our aim was to study the
Jean-Marie Bard +4 more
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Angiology, 2008
We investigated the association of apolipoproteins AI and B in relation to the prevalence of metabolic syndrome in a random sample of cardiovascular disease— free adults from the ATTICA study (1,514 men, aged 18-87 y; 1,528 women, aged 18-89 y). Metabolic syndrome was defined according to the National Cholesterol Education Program Adult Treatment ...
Pitsavos, C. +4 more
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We investigated the association of apolipoproteins AI and B in relation to the prevalence of metabolic syndrome in a random sample of cardiovascular disease— free adults from the ATTICA study (1,514 men, aged 18-87 y; 1,528 women, aged 18-89 y). Metabolic syndrome was defined according to the National Cholesterol Education Program Adult Treatment ...
Pitsavos, C. +4 more
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Arteriosclerosis, Thrombosis, and Vascular Biology, 1997
Abstract Apolipoprotein (apo) B-67 is a truncated form of apoB-100 due to deletion of an adenine at cDNA 9327. Heterozygotes have one allele making apoB-100; therefore, plasma apoB levels would be predicted to be at least 50% of normal. However, apoB-67 heterozygotes have total plasma apoB levels that are 24% of normal.
Francine K. Welty +5 more
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Abstract Apolipoprotein (apo) B-67 is a truncated form of apoB-100 due to deletion of an adenine at cDNA 9327. Heterozygotes have one allele making apoB-100; therefore, plasma apoB levels would be predicted to be at least 50% of normal. However, apoB-67 heterozygotes have total plasma apoB levels that are 24% of normal.
Francine K. Welty +5 more
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The Role of Apolipoprotein E and Apolipoprotein B in Atherosclerosis
1991Two apolipoproteins (apo-), apo-B100 and apo-E, are extremely important in lipoprotein metabolism and in the development of accelerated atherosclerosis. Their significance stems from their role in binding to the low density lipoprotein (LDL) receptor and mediating the catabolism of lipoproteins via the LDL receptor pathway.
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Variations in apolipoproteins B and A, during the course of myocardial infarction
European Journal of Clinical Investigation, 1978P. Avogaro +7 more
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