Results 31 to 40 of about 37,488 (288)

Oxidized low-density lipoprotein inhibits hepatitis C virus cell entry in human hepatoma cells. [PDF]

, 2006
Cell entry of hepatitis C virus, pseudoparticles (HCVpp) and cell culture grown virus (HCVcc), requires the interaction of viral glycoproteins with CD81 and other as yet unknown cellular factors.
Boullier, Agnès, Lindenbach, Brett D, McKeating, Jane A, Paulson, Matthew, Quehenberger, Oswald, Rice, Charles M, von Hahn, Thomas   +6 more
core   +1 more source

[5] Apolipoprotein B-48

, 1996
Publisher Summary The methods discussed in this chapter provide fairly simple, sensitive, and reliable means of determining the content of apoB-48 and apoB-100 in Sf>12 lipoproteins, by analytical sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), with subsequent conventional protein staining and gel scanning.
Karpe, F, Hamsten, A, Uffelman, K, Steiner, G   +3 more
openaire   +4 more sources

Vascular function and cardiovascular risk factors in women with severe flushing [PDF]

, 2011
Background: Seventy per cent of postmenopausal women suffer from hot flushes causing significant morbidity in 25%. Oestrogen replacement provides symptom relief, but its use has declined following safety issues and there is, as yet, no good alternative ...
Andrikoula, Bechlioulis, Brockie, Caballero, Ferrell, Freedman, Freeman, Gambacciani, Ginsburg, Huang, Keating, Khan, Khan, Kronenberg, Kubli, Leal, Lerman, Lobo, Martin, Modena, Morris, Nilsson, Noon, Ramsay, Ramsay, Sattar, The Emerging Risk Factors Collaboration, Thurston, Wardell   +28 more
core   +1 more source

Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders. [PDF]

, 2016
Apolipoprotein (apo) E was initially described as a lipid transport protein and major ligand for low density lipoprotein (LDL) receptors with a role in cholesterol metabolism and cardiovascular disease.
Mahley, Robert W
core   +1 more source

Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila [PDF]

, 2008
Apolipoprotein D (ApoD) expression increases in several neurological disorders and in spinal cord injury. We provide a report of a physiological role for human ApoD (hApoD): Flies overexpressing hApoD are long-lived and protected against stress ...
Ahn, Boyles, Boyles, Butterfield, D. W. Walker, Desai, Do Carmo, Duffy, Guti  rrez, J. Muffat, Kalman, Lechner, Morais Cabral, Navarro, Oakley, Pfaffl, Provost, Provost, Rassart, S. Benzer, Sanchez, Sutcliffe, Terrisse, Thomas, Thomas, Toroser, Vogt, Walker, Wallace, Walsh, Weech   +30 more
core   +3 more sources

Insulin modulation of newly synthesized apolipoproteins B-100 and B-48 in human fetal intestine: Gene expression and mRNA editing are not involved [PDF]

, 1996
We investigated insulin's effect on intestinal lipid transport and, particularly, the biogenesis of apolipoproteins crucial to lipoprotein secretion. Adding insulin (3 mU) to the serum-free medium of cultured jejunal explants from human fetuses (17–20 ...
Delvin, Edgard, Levy, Emile, Ménard, Daniel, Nguyen, Thanh Dung, Sinnett, Daniel, Thibault, Louise   +5 more
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

APOLIPOPROTEIN A1 AND B ENHANCE INTERNALIZATION AND INFECTION OF DENGUE VIRUS SEROTYPE 2 (DENV2) IN HUH-7 CELL LINES

International Journal of Infectious Diseases, 2023
Intro: Previous studies have suggested an association between HDL, LDL cholesterol and dengue severity; however, the molecules involved in dengue virus (DENV) entry remain poorly understood. This study aims to determine the effects of apolipoproteins A1,
R. Ahmad, F. Mohd Nor, W. Seok Mui, T.H. Abdul Rahman   +3 more
doaj  

Effects of overexpression of the amino-terminal fragment of apolipoprotein B on apolipoprotein B and lipoprotein production [PDF]

Journal of Lipid Research, 2000
In vitro studies have shown that the binding site for microsomal triglyceride transfer protein (MTP) is within the first 17% of apoB (apoB-17). Expression of apoB-48 in McArdle cells decreases endogenous lipoprotein production; however, overexpression of human apoB in transgenic mice does not decrease endogenous mouse apoB expression.
Zhaohui Li, Jane M. Glick, Mason W. Freeman, Xinzhong Wang, Ling Pang, Yuko Kako, Ira J. Goldberg   +6 more
openaire   +4 more sources

Cerebral Amyloid Angiopathy Is Associated With Higher R2 Relaxation Rate: An MRI and Pathology Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral amyloid angiopathy (CAA) involves β‐amyloid deposition in the walls of cortical and leptomeningeal small vessels. Transverse relaxation rate (R2) is a major source of contrast in MRI. This study tested the hypothesis that CAA is associated with R2, extracted the spatial pattern of CAA‐related R2 abnormalities, and evaluated ...
Md Tahmid Yasar, Arnold M. Evia, Mahir Tazwar, Sue E. Leurgans, David A. Bennett, Julie A. Schneider, Konstantinos Arfanakis   +6 more
wiley   +1 more source