PLoS Pathogens, 2014 Apolipoprotein B (ApoB) and ApoE have been shown to participate in the particle formation and the tissue tropism of hepatitis C virus (HCV), but their precise roles remain uncertain.
Takasuke Fukuhara +13 more
doaj +1 more source
PLoS ONE, 2014 ObjectiveIntensive as compared to mild statin therapy has been proven to be superior in improving cardiovascular outcome, whereas the effects of intensive statin therapy on inflammation and lipoprotein biomarkers are not well defined.MethodsThis study ...
Tomohiro Yamasaki +7 more
doaj +1 more source
Peripheral blood mitochondrial DNA content in relation to circulating metabolites and inflammatory markers: a population study [PDF]
, 2017 Mitochondrial DNA (mtDNA) content might undergo significant changes caused by metabolic derangements, oxidative stress and inflammation that lead to development and progression of cardiovascular diseases.
Brguljan-Hitij, Jana +13 more
core +2 more sources
Estimating the level of carbamoylated plasma non-high-density lipoproteins using infrared spectroscopy [PDF]
, 2019 Background: The increased cardiovascular morbidity and mortality observed in chronic kidney disease (CKD) patients can be partly explained by the presence of carbamoylated lipoproteins. Lipid profiles can be determined with infrared spectroscopy. In this
De Baene, Linde +5 more
core +1 more source
Which lipid measurement should we monitor? An analysis of the LIPID study [PDF]
, 2014 OBJECTIVES: To evaluate the optimal lipid to measure in monitoring patients, we assessed three factors that influence the choice of monitoring tests: (1) clinical validity; (2) responsiveness to therapy changes and (3) the size of the long-term ‘signal ...
Glasziou, Paul P. +4 more
core +1 more source
ApoC-III and visceral adipose tissue contribute to paradoxically normal triglyceride levels in insulin-resistant African-American women [PDF]
, 2014 Background: African-Americans are more insulin-resistant than whites but have lower triglyceride (TG) concentrations. The metabolic basis for this is unknown. Our goal was to determine in a cross-sectional study the effect of insulin resistance, visceral
Courville, Amber B +6 more
core +1 more source
Polarized secretion of newly synthesized lipoproteins by the Caco-2 human intestinal cell line
Journal of Lipid Research, 1987 Lipoprotein secretion by Caco-2 cells, a human intestinal cell line, was studied in cells grown on inserts containing a Millipore filter (0.45 micron), separating secretory products from the apical and basolateral membranes into separate chambers.
M G Traber, H J Kayden, M J Rindler
doaj +1 more source
Postprandial apoE isoform and conformational changes associated with VLDL lipolysis products modulate monocyte inflammation. [PDF]
, 2012 ObjectivePostprandial hyperlipemia, characterized by increased circulating very low-density lipoproteins (VLDL) and circulating lipopolysaccharide (LPS), has been proposed as a mechanism of vascular injury.
Altman, Robin +10 more
core +3 more sources
Influence of liver cancer on lipid and lipoprotein metabolism
Lipids in Health and Disease, 2006 Liver plays a key role in the metabolism of plasma apolipoproteins, endogenous lipids and lipoproteins. Hepatocellular carcinoma (HCC) is one of the most common fatal malignant tumors in China and in other Southeast Asian countries.
Nilsson-Ehle Peter +2 more
doaj +1 more source
Nanoparticles-cell association predicted by protein corona fingerprints [PDF]
, 2016 In a physiological environment (e.g., blood and interstitial fluids) nanoparticles (NPs) will bind proteins shaping a "protein corona" layer. The long-lived protein layer tightly bound to the NP surface is referred to as the hard corona (HC) and encodes ...
Caracciolo, Giulio +6 more
core +1 more source