Results 31 to 40 of about 23,927 (115)

Effect of N-3 Polyunsaturated Fatty Acids on Lipid Composition in Familial Hypercholesterolemia: A Randomized Crossover Trial

Biomedicines, 2022
Individuals with familial hypercholesterolemia (FH) have an increased risk of cardiovascular disease. Treatment is mainly low-density lipoprotein cholesterol (LDL-C) reduction.
Liv Nesse Hande, Christian Kjellmo, Kristin Pettersen, Stefan Ljunggren, Helen Karlsson, Karin Cederbrant, Maritha Marcusson-Ståhl, Anders Hovland, Knut Tore Lappegård   +8 more
doaj   +1 more source

Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes

Communications Medicine, 2023
Schmidt et al. evaluate the effects of elevated circulating concentrations of cholesterol-containing lipoproteins and apolipoproteins. Effects are seen on measures of atherosclerosis, blood pressure, c-reactive protein, coronary heart disease, heart ...
Amand F. Schmidt, Roshni Joshi, Maria Gordillo-Marañón, Fotios Drenos, Pimphen Charoen, Claudia Giambartolomei, Joshua C. Bis, Tom R. Gaunt, Alun D. Hughes, Deborah A. Lawlor, Andrew Wong, Jackie F. Price, Nishi Chaturvedi, Goya Wannamethee, Nora Franceschini, Mika Kivimaki, Aroon D. Hingorani, Chris Finan   +17 more
doaj   +1 more source

Apolipoprotein E allelic influence on human cerebrospinal fluid apolipoproteins

Journal of Lipid Research, 1998
The major apolipoproteins (apo) on human cerebrospinal fluid lipoproteins are apoA-I and apoE. Given the association between inheritance of the ε4 allele of the apoE gene (APOE4) and increased susceptibility to Alzheimer's disease, we tested the ...
Kathleen S. Montine, Casey N. Bassett, Joyce J. Ou, William R. Markesbery, Larry L. Swift, Thomas J. Montine   +5 more
doaj   +1 more source

ApoA-IV metabolism in the rat: role of lipoprotein lipase and apolipoprotein transfer.

Journal of Lipid Research, 1990
Factors influencing the association of apoA-IV with high density lipoproteins (HDL) were investigated by employing a crossed immunoelectrophoresis assay to estimate the distribution of rat plasma apoA-IV between the lipoprotein-free and HDL fractions ...
M Lefevre, M Y Chuang, P S Roheim
doaj   +1 more source

Increased production of apolipoprotein B and its lipoproteins by oleic acid in Caco-2 cells.

Journal of Lipid Research, 1990
The production of lipids, apolipoproteins (apo), and lipoproteins induced by oleic acid has been examined in Caco-2 cells. The rates of accumulation in the control medium of 15-day-old Caco-2 cells of triglycerides, unesterified cholesterol, and ...
N Dashti, EA Smith, P Alaupovic
doaj   +1 more source

One-step screening method for the polymorphism of apolipoproteins A-I, A-II, and A-IV

Journal of Lipid Research, 1982
Apolipoprotein A-I exhibits a polymorphism that can be easily investigated in native serum by a simple method involving incubation of serum in the presence of decylsulfate and beta-mercaptoethanol and subsequent isoelectric focusing.
H J Menzel, R G Kladetzky, G Assmann
doaj   +1 more source

Apolipoproteins of the orotic acid fatty liver: implications for the biogenesis of plasma lipoproteins.

Journal of Lipid Research, 1988
Rats fed orotic acid develop fatty livers characterized by triglyceride-laden, membrane-bounded vesicles designated ''liposomes.'' We have measured the levels of apolipoproteins in isolated liposomes and other subcellular fractions by SDS-polyacrylamide ...
R Hay, R Fleming, W O'Connell, J Kirschner, W Oppliger   +4 more
doaj   +1 more source

Association of lipid metabolism with pneumonia risk in under-five children in China

Jornal de Pediatria, 2023
Objective: The relationship between lipid metabolism and pneumonia in under-five children remains unclear. The aim of the study was to explore the association of several lipids, lipoproteins and apolipoproteins with the risk of childhood pneumonia, and ...
Qianhan Wang, Yonghong Miao, Qiongdan Zhao   +2 more
doaj   +1 more source

Amphipathic α-helices in apolipoproteins are crucial to the formation of infectious hepatitis C virus particles.

PLoS Pathogens, 2014
Apolipoprotein B (ApoB) and ApoE have been shown to participate in the particle formation and the tissue tropism of hepatitis C virus (HCV), but their precise roles remain uncertain.
Takasuke Fukuhara, Masami Wada, Shota Nakamura, Chikako Ono, Mai Shiokawa, Satomi Yamamoto, Takashi Motomura, Toru Okamoto, Daisuke Okuzaki, Masahiro Yamamoto, Izumu Saito, Takaji Wakita, Kazuhiko Koike, Yoshiharu Matsuura   +13 more
doaj   +1 more source

The effects of apolipoprotein B depletion on HDL subspecies composition and function[S]

Journal of Lipid Research, 2016
HDL cholesterol (HDL-C) efflux function may be a more robust biomarker of coronary artery disease risk than HDL-C. To study HDL function, apoB-containing lipoproteins are precipitated from serum.
W. Sean Davidson, Anna Heink, Hannah Sexmith, John T. Melchior, Scott M. Gordon, Zsuzsanna Kuklenyik, Laura Woollett, John R. Barr, Jeffrey I. Jones, Christopher A. Toth, Amy S. Shah   +10 more
doaj   +1 more source