Results 41 to 50 of about 23,927 (115)

Surface pressure-dependent conformation change of apolipoprotein-derived amphipathic α-helices

Journal of Lipid Research, 2013
Amphipathic α-helices (AαH) are the primary structural motif of exchangeable apolipoproteins. AαHs in exchangeable apolipoproteins adsorb, remodel, and desorb at the surface of plasma lipoproteins in response to changes in their size or composition.
Matthew A. Mitsche, Donald M. Small
doaj   +1 more source

Role of apolipoproteins E and C in type V hyperlipoproteinemia.

Journal of Lipid Research, 1988
Type V hyperlipoproteinemia is characterized by elevations of chylomicron (CM) and very low density lipoprotein (VLDL) triglycerides. The development of this lipid disorder involves a multitude of metabolic derangements including deficient clearance of ...
T Kuusi, M R Taskinen, T Solakivi, R Kauppinen-Mäkelin   +3 more
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Mass Spectrometric Studies of Apolipoprotein Proteoforms and Their Role in Lipid Metabolism and Type 2 Diabetes

Proteomes, 2017
Apolipoproteins function as structural components of lipoprotein particles, cofactors for enzymes, and ligands for cell-surface receptors. Most of the apoliporoteins exhibit proteoforms, arising from single nucleotide polymorphisms (SNPs) and post ...
Dobrin Nedelkov
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Overexpression ofapoC-III produces lesser hypertriglyceridemia in apoB-48-only gene-targeted micethan in apoB-100-only mice

Journal of Lipid Research, 2004
The adaptive value of apolipoprotein B-48 (apoB-48), thetruncated form of apoB produced by the intestine, in lipid metabolism remainsunclear. We crossed human apoC-III transgenic mice with mice expressing eitherapoB-48 only (apoB48/48) or apoB-100 only ...
Karin Conde-Knape, Kenta Okada, Rajasekhar Ramakrishnan, NeilS. Shachter   +3 more
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Age-specific and sex-specific reference intervals for non-fasting lipids and apolipoproteins in 7260 healthy Chinese children and adolescents measured with an Olympus AU5400 analyser: a cross-sectional study

BMJ Open, 2019
Aims Ethnic, demographic, lifestyle, genetic and environmental factors influence lipids and apolipoproteins. The aim of this study was to establish age-specific and gender-specific reference intervals for non-fasting lipids and apolipoproteins in healthy
Junjie Liu, Yanpeng Dai, Enwu Yuan, Yushan Li, Quanxian Wang, Linkai Wang, Yanhua Su   +6 more
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Comparison of efficacy of intensive versus mild pitavastatin therapy on lipid and inflammation biomarkers in hypertensive patients with dyslipidemia.

PLoS ONE, 2014
ObjectiveIntensive as compared to mild statin therapy has been proven to be superior in improving cardiovascular outcome, whereas the effects of intensive statin therapy on inflammation and lipoprotein biomarkers are not well defined.MethodsThis study ...
Tomohiro Yamasaki, Yoshio Iwashima, Subrina Jesmin, Yuko Ohta, Hiroshi Kusunoki, Shin-ichiro Hayashi, Takeshi Horio, Yuhei Kawano   +7 more
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Computer programs to identify and classify amphipathic alpha helical domains.

Journal of Lipid Research, 1992
The amphipathic alpha helix is an often-encountered secondary structural motif in biologically active peptides and proteins. An amphipathic helix is defined as an alpha helix with opposing polar and nonpolar faces oriented along the long axis of the ...
MK Jones, GM Anantharamaiah, JP Segrest
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Value of C-Reactive Protein as a Risk Factor for Acute Coronary Syndrome: A Comparison with Apolipoprotein Concentrations and Lipid Profile

Mediators of Inflammation, 2012
Objective. To investigate whether assessment of C-reactive protein (CRP) and apolipoproteins, besides the traditional lipid profile, enhances the assessment process for the risk of acute coronary syndrome (ACS). Methods.
Magdalena Krintus, Marek Kozinski, Anna Stefanska, Marcin Sawicki, Karolina Obonska, Tomasz Fabiszak, Jacek Kubica, Grazyna Sypniewska   +7 more
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Apolipoproteins in Psoriasis: The Effect of Acitretin Treatment and UVB Phototherapy

Metabolites
Background: Psoriasis is a chronic, multi-system inflammatory disease frequently associated with metabolic syndrome and lipid disturbances. Apolipoproteins, as essential regulators of lipid metabolism, may play a critical role in these metabolic ...
Hanna Myśliwiec, Dorota Kozłowska, Katarzyna Hodun, Bartłomiej Łukaszuk, Agnieszka Owczarczyk-Saczonek, Adrian Chabowski, Iwona Flisiak   +6 more
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LPL gene variants affect apoC-III response to combination therapy of statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia

Journal of Lipid Research, 2012
ApoC-III is a proatherogenic protein associated with elevated triglycerides; its deficiency is associated with reduced atherosclerosis. Mixed dyslipidemia, characterized by elevated triglyceride and apoC-III levels and low HDL cholesterol level, with or ...
Ariel Brautbar, Salim S. Virani, John Belmont, Vijay Nambi, Peter H. Jones, Christie M. Ballantyne   +5 more
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