Results 121 to 130 of about 18,813,566 (369)

OXidative Stress PREDictor: A Supervised Learning Approach for Annotating Cellular Oxidative Stress States in Inflammatory Cells

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
OxSpred, an eXtreme‐Gradient‐Boosting‐‐based supervised learning model, accurately annotates oxidative stress in innate immune cells at the single‐cell level, providing interpretable embeddings with significant biological relevance. This innovative tool revolutionizes the understanding of innate immune cell functions during inflammation and enhances ...
Po‐Yuan Chen, Tai‐Ming Ko
wiley   +1 more source

Increased production of apolipoprotein B and its lipoproteins by oleic acid in Caco-2 cells.

open access: yesJournal of Lipid Research, 1990
The production of lipids, apolipoproteins (apo), and lipoproteins induced by oleic acid has been examined in Caco-2 cells. The rates of accumulation in the control medium of 15-day-old Caco-2 cells of triglycerides, unesterified cholesterol, and ...
N Dashti, EA Smith, P Alaupovic
doaj  

Nucleotide sequence of the cynomolgus monkey apolipoprotein E cDNA [PDF]

open access: green, 1989
K.R. Marotti   +4 more
openalex   +1 more source

AI‐Driven Microphysiological Systems for Advancing Nanoparticle Therapeutics

open access: yesAdvanced Intelligent Systems, EarlyView.
This review outlines recent advances in integrating artificial intelligence with microphysiological systems for nanoparticle evaluation. It highlights data‐driven optimization, image‐based prediction, and AI‐enabled analysis frameworks that advance translational research and support the development of personalized nanomedicine. Nanoparticles (NPs) play
Yedam Lee   +3 more
wiley   +1 more source

Apolipoproteins of the orotic acid fatty liver: implications for the biogenesis of plasma lipoproteins.

open access: yesJournal of Lipid Research, 1988
Rats fed orotic acid develop fatty livers characterized by triglyceride-laden, membrane-bounded vesicles designated ''liposomes.'' We have measured the levels of apolipoproteins in isolated liposomes and other subcellular fractions by SDS-polyacrylamide ...
R Hay   +4 more
doaj  

The Role of SLC39A8.p.(Ala391Thr) in Schizophrenia Symptom Severity and Cognitive Ability: Cross‐Sectional Studies of Schizophrenia and the General UK Population

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT The missense SNP NC_000004.12:g.102267552C>T (also known as SLC39A8.p.(Ala391Thr), rs13107325) in SLC39A8 encodes a zinc transporter. This SNP has been linked to schizophrenia and is the likely causal variant for one of the genome‐wide association loci associated with the disorder. Using regression analyses, we tested whether the schizophrenia‐
Sophie E. Smart   +12 more
wiley   +1 more source

Effects of oleate and insulin on the production rates and cellular mRNA concentrations of apolipoproteins in HepG2 cells.

open access: yesJournal of Lipid Research, 1989
We have reported previously that, in HepG2 cells, there is a lack of coordinate induction of triglyceride and apolipoprotein (apo) production by oleate and that insulin inhibits the production of triglyceride-rich, apoB-containing lipoproteins.
N Dashti, D L Williams, P Alaupovic
doaj  

Human apolipoprotein E expression in Escherichia coli: structural and functional identity of the bacterially produced protein with plasma apolipoprotein E. [PDF]

open access: green, 1985
Thomas Vogel   +9 more
openalex   +1 more source

Genetics of Response to ECT, TMS, Ketamine and Esketamine

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Treatment‐resistant mood disorders are often managed with intensive interventions that include electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), ketamine, and esketamine, but the role of genetics in clinical response to those interventions is yet to be clearly determined.
Clio E. Franklin   +18 more
wiley   +1 more source

Abnormalities in lipoproteins of d < 1.006 g/ml in familial lecithin:cholesterol acyltransferase deficiency

open access: yesJournal of Lipid Research, 1980
Studies of different sized lipoproteins of d < 1.006 g/ml from patients with familial lecithin:cholesterol acyltransferase deficiency have yielded new evidence of abnormalities in this lipoprotein class.
J A Glomset   +6 more
doaj  

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