Microglial morphology changes in response to damage by Aβ and aging result in significant reductions in cell surface area. Transcriptomic analyses suggest that fatty acid synthesis and triacylglycerol formation drive redistribution of surface membrane into intracellular lipid droplets.
G. William Rebeck +4 more
wiley +1 more source
ADP-Ribosylation in Experimental Atherosclerosis: A Potential Link Between Dyslipidemia and Inflammation in Cardiovascular Disease. [PDF]
Santinelli-Pestana DV +15 more
europepmc +1 more source
Contrast Agents for Enhanced Bioimaging: A Comprehensive Review
Contrast agents, especially those that are nanoparticle‐based, are revolutionizing bioimaging by enabling highly sensitive, specific, and early‐stage diagnosis of diseases like cancer, using clinical imaging modalities such as CT, MRI, PET, and SPECT.
Paulo Sérgio Taube +17 more
wiley +1 more source
The lysophosphatidylcholine-HIF-1α axis enhances apolipoprotein E sialylation and promotes electronegative LDL accumulation. [PDF]
Chan HC +11 more
europepmc +1 more source
Natural History of Chronic Kidney Disease in Sickle Cell Disease
ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley +1 more source
Dried blood spot sample extraction for metabolomics and proteomics profiling for clinical trials: a descriptive exploratory study. [PDF]
Fägerstam S +4 more
europepmc +1 more source
APOs as promising prognostic biomarkers: correlation with tumor-infiltrating leukocytes in endometrial cancer. [PDF]
Zhou L +7 more
europepmc +1 more source
Lipid transport mechanisms in human ABCA family transporters: a structural perspective. [PDF]
Dolai S, Alam A.
europepmc +1 more source
Context-Dependent Effects of Apolipoprotein A2 on Lipid Metabolism and Atherogenesis. [PDF]
Zvintzou E +9 more
europepmc +1 more source
Multi-omics identification of immune-related biomarkers predicting tofacitinib response in rheumatoid arthritis. [PDF]
Lu F +6 more
europepmc +1 more source

