Results 211 to 220 of about 18,538,974 (359)

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

A Robust Serum Proteomic Signature of the E2 Allele of Apolipoprotein E. [PDF]

Adv Sci (Weinh)
Sebastiani P, Reed E, Chandler KB, Lopez P, Lords H, Bae H, Costello CE, Au M, Deng LL, Li M, Xiang Q, Noh H, Pflieger L, Funk C, Rappaport N, Nygaard M, Short MI, Brent M, Monti S, Andersen SL, Perls TT.   +20 more
europepmc   +1 more source

Molecular Details of the Apolipoprotein E and the Amyloid Beta Peptide Interaction: Analysis of a Potential Binding Site Responsible for ApoE4 Misfolding [PDF]

, 2010
Alex Perálvarez‐Marín, Jinghui Luo, Jean‐Didier Maréchal, Sebastian K.T.S. Wärmländer, Astrid Gräslund   +4 more
openalex   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Dysapolipoproteinaemia Influences the Relationship Between Very Low-Density Lipoprotein Cholesterol and Intra-Pancreatic Fat Deposition in Humans. [PDF]

Nutrients
Liu Y, Skudder-Hill L, Ko J, Shamaitijiang X, Sequeira-Bisson IR, Petrov MS.   +5 more
europepmc   +1 more source

Examining the association between Apolipoprotein E (APOE) and self-reported sleep disturbances in non-demented older adults

, 2015
Angeliki Tsapanou, Nikolaos Scarmeas, Yian Gu, Jennifer J. Manly, Nicole Schupf, Yaakov Stern, Sandra Barral   +6 more
openalex   +1 more source

Interplay Between Sex and Cytosine‐Adenine‐Guanine‐Age Product Score in Huntington's Disease: Clinical and Neuroimaging Perspectives

Movement Disorders, EarlyView.
Abstract Background Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a cytosine‐adenine‐guanine (CAG) repeat expansion in the huntingtin gene. The disease exhibits sex‐related differences in symptomatology and disease progression, but the effect on brain structural biomarkers and the interaction between sex and CAG‐age ...
Jingwen Yao, Grayson Feng, Guowen Shao, Zexi Wang, Adys Mendizabal, Donatello Telesca, Kaiying Fang, Lola Ibragimova, Juwairia Shoaib, Melanie A. Morrison, Janine M. Lupo   +10 more
wiley   +1 more source

Apolipoprotein E ( APOE ) [PDF]

Science-Business eXchange, 2012
openaire   +3 more sources

People living with HIV on modern antiretrovirals do not display a pro-atherogenic lipid profile and have similar body composition compared to healthy controls. [PDF]

HIV Med
Savinelli S, Heeney A, Tinago W, Garcia Leon AA, McGettrick P, Cotter AG, Walsh I, Fitzgibbon M, Sabin CA, Mallon PWG, Feeney ER, HIV UPBEAT study group.   +11 more
europepmc   +1 more source