Characterisation of pregnancy-induced alterations in apolipoproteins and their associations with maternal metabolic risk factors and offspring birth outcomes: a preconception and longitudinal cohort study. [PDF]
Chen L +11 more
europepmc +1 more source
Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley +1 more source
"Good" fats, bad news: HDL-delivered vitamin E shields tumors from ferroptosis. [PDF]
Choi DW, Lee EW.
europepmc +1 more source
Abstract Klotho, a pleiotropic protein initially identified for its role in kidney function, has garnered significant attention for its neuroprotective properties in various neurodegenerative diseases. It regulates key processes, such as oxidative stress, neuroinflammation, synaptic plasticity and myelination, all crucial for maintaining neuronal ...
Amir Arsalan Ghahari +7 more
wiley +1 more source
Evidence from Mendelian randomization analysis combined with meta-analysis for the causal validation of the relationship between 35 blood and urine metabolites and lumbar disc herniation. [PDF]
Yang J, Xu W, Chen D, Yang H, Zhou Z.
europepmc +1 more source
Early adversity and the comorbidity between metabolic disease and psychopathology
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas +1 more
wiley +1 more source
Visceral fat area loss reduces 10-year atherosclerotic cardiovascular disease risk in Chinese population with type 2 diabetes mellitus: a prospective cohort study. [PDF]
Jin J +9 more
europepmc +1 more source
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira +3 more
wiley +1 more source
Evinacumab Improved the Homozygous Familial Hypercholesterolemia Lipid Metabolism: A Case Report. [PDF]
Matsuda T +9 more
europepmc +1 more source
Precision medicine requires precision proteomics: discordance between proteomic and clinical assays in UK Biobank. [PDF]
Singh B, Tzoulaki I, Mayr M.
europepmc +1 more source

