Results 281 to 290 of about 18,538,974 (359)

Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients

Clinical &Experimental Allergy, EarlyView.
Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna, Christina Morgenstern, Katharina Poglitsch, Tamara Arnoldner, Katharina Gangl, Tina J. Bartosik, Nicholas J. Campion, Aldine Tu, Victoria Stanek, Sven Schneider, Christine Bangert   +10 more
wiley   +1 more source

Apolipoproteins in Psoriasis: The Effect of Acitretin Treatment and UVB Phototherapy. [PDF]

Metabolites
Myśliwiec H, Kozłowska D, Hodun K, Łukaszuk B, Owczarczyk-Saczonek A, Chabowski A, Flisiak I.   +6 more
europepmc   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Insight into the metabolic shifts in Graves' hyperthyroidism: a study of acylcarnitine and lipid profiles. [PDF]

Eur Thyroid J
Neset MT, Ulvik A, Løvås K, Laupsa-Borge J, Breivik LE, Stokland AM, Nedrebø BG, Rødahl E, Husebye E, Ueland GÅ, Ueland HO.   +10 more
europepmc   +1 more source

Dynamics of Apolipoprotein J Levels and Metabolic Parameters Following Bariatric Surgery

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Bariatric surgery has emerged as a potent intervention for ameliorating insulin resistance and its associated comorbidities in obese patients. Apolipoprotein J (ApoJ) and adiponectin are closely associated with insulin resistance and sensitivity, respectively.
Kellen Cristina da Cruz Rodrigues, Minjin Lee, Yejee Lim, Jennie Young, Brendon Chung, Susan Phillips, Theodore P. Ciaraldi, Young‐Bum Kim   +7 more
wiley   +1 more source

Radiolabeling lipoproteins to study and manage disease. [PDF]

Eur J Nucl Med Mol Imaging
Pérez-Medina C, Fisher EA, Fayad ZA, Mulder WJM, Teunissen AJP.   +4 more
europepmc   +1 more source

The Need to Promote Olfactory Health in Public Health Agendas Across the Globe

Clinical Otolaryngology, EarlyView.
ABSTRACT Background A good sense of smell is essential for physical and mental health, and social wellbeing; however, across the globe, regardless of the setting, national public health agendas never consider smell health. This review aims to summarise the wide‐reaching impact of smell health in public health. Methods Narrative review of the literature
Carl Martin Philpott, Thomas Hummel, Valentina Parma, Matt Lechner, Duncan Boak, Marianna Obrist   +5 more
wiley   +1 more source

Engineering Fusion Proteins for Nanomedicine-Based Cytokine Therapy. [PDF]

Bioconjug Chem
de Dreu A, de Bruin K, Hokke AM, Schrijver DP, Beelen DNH, Verhalle LM, Clavijo Perez MC, Anbergen T, Versteeg I, Maas R, Zwolsman RC, Grao-Roldán C, Bartelet B, Trines MM, Hoorn D, Ros G, Toner YC, Kluza E, Beldman T, Pérez-Medina C, Netea MG, Merkx M, van der Meel R, Mulder WJM.   +23 more
europepmc   +1 more source

Homoharringtonine Promotes FTO Degradation to Suppress LILRB4‐Mediated Immune Evasion in Acute Monocytic Leukaemia

Cell Proliferation, EarlyView.
Homoharringtonine (HHT) suppresses immune evasion in acute monocytic leukaemia (AML‐M5) by attenuating the FTO/m6A/LILRB4 axis, thereby enhancing CD8+ T cell cytotoxicity. ABSTRACT Acute monocytic leukaemia, a subtype of acute myeloid leukaemia (AML), is a highly aggressive malignancy characterised by a poor prognosis, primarily due to the ability of ...
Fangfang Huang, Xiang Luo, Mengyu Zhang, Le Jin, Wenxin Sun, Peihan Chen, Xiuli Hong, Chenyu Xu, Meizhi Jiang, Die Hu, Bin Zhang, Shengwei Hu, Chuanjiang Yang, Rui Gao, Jinzhang Zeng, Quanyi Lu, Qiang Luo, Jun Wu, Siming Chen   +18 more
wiley   +1 more source

Apolipoprotein and menopausal status are significant influencing factors for diabetic retinopathy in type II diabetes mellitus women. [PDF]

Sci Rep
Pei X, Yao X, Qi D, Yang Y, Fan S, Li Z.
europepmc   +1 more source