Protein corona critically affects the bio-behaviors of SARS-CoV-2 [PDF]
arXiv, 2021 The outbreak of the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become a worldwide public health crisis. When the SARS-CoV-2 enters the biological fluids in the human body, different types of biomolecules (in particular proteins) may adsorb on its surface and alter its infection ability.
arxiv
Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila [PDF]
, 2008 Apolipoprotein D (ApoD) expression increases in several neurological disorders and in spinal cord injury. We provide a report of a physiological role for human ApoD (hApoD): Flies overexpressing hApoD are long-lived and protected against stress ...
Ahn +30 more
core +3 more sources
Unresolved excess accumulation of myelin-derived cholesterol contributes to scar formation after spinal cord injury [PDF]
arXiv, 2022 Background: Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered as a barrier for regeneration in central nervous system (CNS), while the intrinsic mechanism of scar-forming after spinal cord injury has not been completed deciphered ...
arxiv
Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders. [PDF]
, 2016 Apolipoprotein (apo) E was initially described as a lipid transport protein and major ligand for low density lipoprotein (LDL) receptors with a role in cholesterol metabolism and cardiovascular disease.
Mahley, Robert W
core +1 more source
Biology, 2022 Angiogenin (ANG), a multifunctional protein known to induce blood vessel formation, is a potential biomarker for cardiovascular diseases; however, whether it is affected by vitamin D supplementation is not known.
Ghadeer M. Aldawsari +9 more
doaj +1 more source
Alzheimer Disease is Associated with Isotropic Ocular Enlargement [PDF]
arXiv, 2023 Recent studies have documented ocular changes in dementia patients, especially Alzheimer Disease (AD). In this study, we explored the change of eye size and eye shape in dementia, including AD patients. The eyeball volume and diameters were estimated via T1-weighted brain magnetic resonance (MR) images in the OASIS-3 database which included 83 AD, 247 ...
arxiv
Vascular function and cardiovascular risk factors in women with severe flushing [PDF]
, 2011 Background: Seventy per cent of postmenopausal women suffer from hot flushes causing significant morbidity in 25%. Oestrogen replacement provides symptom relief, but its use has declined following safety issues and there is, as yet, no good alternative ...
Andrikoula +28 more
core +1 more source
Complement activation and protein adsorption by carbon nanotubes [PDF]
, 2006 As a first step to validate the use of carbon nanotubes as novel vaccine or drug delivery devices, their interaction with a part of the human immune system, complement, has been explored.
Flahaut, Emmanuel +5 more
core +2 more sources
Characterisation of Antigen B Protein Species Present in the Hydatid Cyst Fluid of Echinococcus canadensis G7 Genotype. [PDF]
PLoS Neglected Tropical Diseases, 2017 The larva of cestodes belonging to the Echinococcus granulosus sensu lato (s.l.) complex causes cystic echinococcosis (CE). It is a globally distributed zoonosis with significant economic and public health impact.
Ana Maite Folle +9 more
doaj +1 more source
Accounting for iron-related off-target binding effects of 18F-AV1451 PET in the evaluation of cognition and microstructure in APOE-e4+ MCI [PDF]
arXiv, 2022 The pathology of Alzheimer's disease (AD) and mild cognitive impairment (MCI) is characterized by the presence of beta-amyloid extracellular plaques and neurofibrillary tangles containing hyper-phosphorylated tau. Individuals carrying the apolipoprotein E-e4 (APOE-e4) allele are at increased risk of cognitive decline and developing AD pathology.
arxiv