The effects of apomorphine on paracetamol-induced hepatotoxicity in rats
It is becoming progressively more understandable that overdose of paracetamol in both humans and animals causes severe hepatotoxicity. Apomorphine is known as a neuroprotective agent.
Asli Kiraz +7 more
core +1 more source
Therapeutical and experimental usefulness of apomorphine
Apomorphine induces behavioural changes in man in some way similar to those elicited by low doses of the drug in animals. In fact, in man a complex symptomatology, in which sedation and psycho-motor reduction predominates, is elicited by non-emetic doses
GESSA GL +4 more
core
Biphasic effect of apomorphine on rat nociception and effect of dopamine D-2 receptor antagonists [PDF]
Studies on the effect of dopaminergic agonists in behavioral measures of nociception have gathered numerous but rather conflicting data. We studied the effects of the D-1/D-2 receptor agonist apomorphine, as well as the modulatory effects of (S ...
Laurido, Claudio +4 more
core
Increased paroxysmal activity of partial seizures in man by apomorphine.
In order to study the role of dopamine (DA) in the regulation of seizure mechanisms in man, a non-emetic dose of apomorphine, a direct stimulant of DA receptors, was administered to eight patients effected by different types of epilepsy.
DEL ZOMPO, MARIA +7 more
core
Agentes dopaminérgicos e o tratamento da disfunção erétil
The understanding of the scientific basis of the erectile function expanded rapidly the range of therapies for treating erectile dysfunction in recent years.
Neves Gilda +3 more
doaj
Continuous apomorphine infusion modulates cortical hyperexcitability and abnormal plasticity in Parkinson's disease. [PDF]
De Bartolo MI +12 more
europepmc +1 more source
Tryptophan Supplementation Reduces Schizophrenia-Like Symptoms in Apomorphine Treated Rats: Role of D2, GABA, and Glutamate Receptor Expression. [PDF]
Nawaz S +5 more
europepmc +1 more source
Apomorphine and psilocybin to improve recovery from coma in the intensive care unit: protocol for a prospective, open-label, dose-escalation study. [PDF]
Eigenbrodt AK +7 more
europepmc +1 more source
Self-inhibitory dopamine-receptors and central effects of apomorphine.
Apomorphine, a central dopamine-receptor agonist, is well known to produce excitatory effects in animals. However, low doses exert depressant effects as hypomotility, sedation and sleep.
Porceddu ML +3 more
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