Results 111 to 120 of about 21,736 (211)

PINK1 homozygous W437X mutation in a patient with apparent dominant transmission of parkinsonism. [PDF]

, 2006
We analyzed the PINK1 gene in 58 patients with early-onset Parkinsonism and detected the homozygous mutation W437X in 1 patient. The clinical phenotype was characterized by early onset (22 years of age), good re- sponse to levodopa, early fluctuations ...
CRISCUOLO C, DALLAPICCOLA B, DE MICHELE, GIUSEPPE, DE ROSA, ANNA, FILLA, ALESSANDRO, MANCINI P, MARONGIU R, SALVATORE, ELENA, VALENTE EM, VARRONE A, VOLPE G   +10 more
core  

Effects of chronic mild stress on apomorphine induced behavioral sensitization in different brain regions of rats in relation to serotonin change

Advancements in Life Sciences, 2015
Background: The impacts of unpredictable stressors have influence on neurochemical and behavioral parameters in laboratory animals. Stress induced behavioral changes particularly those associated with anxiety like behavior may activate topographically ...
Muhammad Farhan, Darakshan Jabeen Haleem
doaj  

Non-Targeted Metabolomics Reveal Apomorphine’s Therapeutic Effects and Lysophospholipid Alterations in Steatohepatitis

Antioxidants
Metabolic dysfunction-associated steatohepatitis (MASH), characterized by progressive inflammation and fibrosis, evolves from metabolic dysfunction-associated steatotic liver disease and significantly heightens the risk of cirrhosis and hepatocellular ...
Hideo Ogiso, Kouichi Miura, Ryozo Nagai, Hitoshi Osaka, Kenichi Aizawa   +4 more
doaj   +1 more source

FAUC 213, a highly selective dopamine D4 receptor full antagonist, exhibits atypical antipsychotic properties in behavioural and neurochemical models of schizophrenia [PDF]

, 2018
Rationale: 2-[4-(4-Chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 213) is a highly selective antagonist at the dopamine D4 receptor subtype.
Boeckler, Frank, Feldon, Joram, Ferger, Boris, Gmeiner, Peter, Hübner, Harald, Löber, Stefan, Russig, Holger, Schetz, John, Zhang, Weining   +8 more
core  

Knocking Down the DRD2 by shRNA Expressing Plasmids in the Nucleus Accumbens Prevented the Disrupting Effect of Apomorphine on Prepulse Inhibition in Rat [PDF]

Journal of Sciences, Islamic Republic of Iran, 2015
Prepulse Inhibition (PPI), the objective measure of sensorimotor gating disturbance has being widely used in animal models of schizophrenia. Dopaminergic direct and indirect agonists impair PPI.
M.R. Noori-daloii, A. Shahbazi, S. Alizadeh Zendehrood, A. Shayan Nia, M. Mojarrad, M. Kheirollahi, A. Rashidi-Nezhad, A. Haghparast, F. Zare Mehrjerdi, S. Niknazar, M. Mostowfi, H. Hashemi Sotoobadi, M. Khaksari, A. R. Noori-Daloii, A. Mohammadi   +14 more
doaj  

Cortical nicotinic receptors in Alzheimer's disease and Parkinson's disease [PDF]

, 1991
Lange, Klaus W., Wells, F. R., Rossor, M. N., Jenner, P., Marsden, C. D.   +4 more
core   +1 more source

Apomorphine

Anaesthesia, 1978
  +5 more sources

A role for the basal ganglia in nicotinic modulation of the blink reflex [PDF]

, 1993
Basso, M. A., Evinger, C., Horn, Anja K. E., Manning, K. A., Pellegrini, J. J., Sibony, P. A.   +5 more
core   +1 more source

The effects of sildenafil ciltrate on the lateral geniculate body of adult Wistar rats (Rattus norvegicus)- A histological study [PDF]

, 2010
The histological effect of oral administration of sildenafil citrate (Viagra), commonly used as an aphrodisiac and for the treatment of erectile dysfunction on one of the visual relay centres namely the lateral geniculate body (LGB) of adult Wistar rat ...
Eweka, A, Eweka, AO
core   +1 more source

Mechanisms and Therapeutic Implications of Neuroleptic Atypicality [PDF]

, 2011
Neuroleptics have proven effective for the overall treatment of schizophrenia. The neuroleptic therapy of schizophrenia, however, has been limited by tardive dyskinesia and by the relative inability of neuroleptics to ameliorate the negative symptoms of ...
Javitt, MD, Daniel C.
core   +1 more source