Results 91 to 100 of about 14,827 (208)

Gender disparity in access to advanced therapies for patients with Parkinson’s disease: a retrospective real-word study

Frontiers in Neurology
BackgroundGender differences in the access to advanced therapies for Parkinson’s disease (PD) are poorly investigated.ObjectiveThe objective of this study was to investigate the presence of any gender disparity in the access to advanced therapies for PD ...
Giuseppe Maccarrone, Gennaro Saporito, Patrizia Sucapane, Chiara Rizi, Federico Bruno, Alessia Catalucci, Maria Letizia Pistoia, Alessandra Splendiani, Alessandro Ricci, Ernesto Di Cesare, Marina Rizzo, Rocco Totaro, Francesca Pistoia, Francesca Pistoia   +13 more
doaj   +1 more source

Responses to apomorphine of pigs with different coping characteristics

, 2000
Rationale: Classification of pigs based on the degree of resistance they display in a so-called "backtest" seems, to a certain extent, predictive for their coping strategy.
Schouten, W.G.P., Jong, I.C. de, Cools, A.R., Schrama, J.W., Wiegant, V.M., Bolhuis, J.E., Jong, I.C., de   +6 more
core   +1 more source

Apomorphine in Parkinson’s disease 4th edition

, 2020
Apomorphine is one of the oldest and, at the same time, most potent drugs for the treatment of Parkinson s disease. Its use was for decades inhibited by the occurrence of dopaminergic side effects and the lack of practical equipment for its delivery. But
Odin, Per,, Hagell, Peter,, Kristianstad University., Timpka, Jonathan,   +3 more
core  

Sulfation of R (.) apomorphine in the human liver and duodenum, and its inhibition by mefenamic acid salicylic acid and quercetin

, 2002
The aims were to study the sulfation of R-(-)-apomorphine (hereafter apomorphine) in the human liver and duodenum, and to study the rate of inhibition of apomorphine sulphation by mefenamic acid, salicylic acid and quercetin also in the human liver and ...
R. Spisni, M. Vietri, PIETRABISSA, ANDREA, G.M. Pacifici, F. Mosca, F. Vaglini   +5 more
core   +1 more source

Efficacy of Intranasal Apomorphine in Parkinson's Disease

, 1995
Objective: To suggest that intranasal delivery may offer an effective alternative to subcutaneous injection of apomorphine. Methods: Four patients (3 men, 1 woman) with idiopathic Parkinson's disease, with disabling “on-off” fluctuations in motor ...
Francisco M García, Angel P Sempere, Jacinto Duarte, Maria Dolores Ruiz, Maria Angeles San Jose, Luis Erick Clavería, Francisco Coria, Angel L Mataix   +7 more
core   +1 more source

Apomorphine for prolonged disorders of consciousness: a multimodal open-label studyResearch in context

EClinicalMedicine
Summary: Background: Apomorphine is a dopaminergic candidate therapy to improve recovery in patients with prolonged disorders of consciousness (PDoC). Behavioural improvements were previously described in non-controlled case series, but its efficacy and
Leandro R.D. Sanz, Nicolas Lejeune, Emilie Szymkowicz, Estelle A.C. Bonin, Rajanikant Panda, Arianna Sala, Aurore Thibaut, Rodrigo Huerta-Gutierrez, Nadia Dardenne, David Dikenstein, Sébastien Van Goethem, Didier Ledoux, Roland Hustinx, Johan Stender, Neal M. Farber, Ross D. Zafonte, Nicholas D. Schiff, Steven Laureys, Olivia Gosseries   +18 more
doaj   +1 more source

Progress Toward the Synthesis of Apomorphine: Chiral Auxiliary Mediated Interception of an Intramolecularly Formed N-Acyl Iminium Ion

, 2004
Glaucine, which contains an aporphine skeleton, has been previously synthesized utilizing an intermolecular approach to form an iminium ion for the Pictet-Spengler reaction.
Nuckols, Michel Christian
core  

Quercetin inhibits the sulfation of R(-)-apomorphine in human brain

, 2003
The first aim of this investigation was to study the sulfation of R(-)-apomorphine in human brain. The second aim was to investigate the inhibition of R(-)-apomorphine sulfation by quercetin in human brain.
M. VIETRI, PACIFICI, GIAN MARIA, R. CANTINI, VAGLINI, FRANCESCA   +3 more
core  

Effects of chronic mild stress on apomorphine induced behavioral sensitization in different brain regions of rats in relation to serotonin change

Advancements in Life Sciences, 2015
Background: The impacts of unpredictable stressors have influence on neurochemical and behavioral parameters in laboratory animals. Stress induced behavioral changes particularly those associated with anxiety like behavior may activate topographically ...
Muhammad Farhan, Darakshan Jabeen Haleem
doaj  

Regional neurochemical profile following co-administration of apomorphine and buspirone in an animal model of addiction

Pakistan Journal of Pharmaceutical Sciences
Although dopamine is the primary neurotransmitter mediating the reinforcing outcomes of abused drugs, serotonin (5-hydroxytryptamine; 5HT) also performs an important function in addiction pathophysiology.
Huma Ikram, Darakhshan Jabeen Haleem
doaj   +1 more source