Results 101 to 110 of about 14,827 (208)

Cocaine strongly reduces prepulse inhibition in apomorphine-susceptible rats, but not in apomorphine-unsusceptible rats: regulation by dopamine D2 receptors.

open access: yes, 2006
Contains fulltext : 50736.pdf (Publisher’s version ) (Closed access)Dopaminergic agonists, such as apomorphine and amphetamine, have been shown to drastically reduce prepulse inhibition of the acoustic startle reflex. The effects of the
Elst, M.C.J. van der   +2 more
core   +1 more source

Locomotion and stereotyped behaviours induced by 1-amino-3,5-dimethyladamantane (D 145) and apomorphine in the rat: a comparison

open access: yes, 1986
The locomotion and stereotyped behaviours induced by the two dopamine agonists, 1-amino-3,5-dimethyladamantane (D 145) and apomorphine in rats have been investigated using a holeboard apparatus. Unlike apomorphine, D 145 did not induce compulsive gnawing,
Thomas Ljungberg
core   +1 more source

Apomorphine-induced penile erections in Parkinson's disease

open access: yes, 1998
Penile erections were regularly induced by intermittent subcutaneous injections of apomorphine in five patients with Parkinson's disease (PD) complicated by motor fluctuations.
O'Sullivan, JD, Hughes, AJ
core   +1 more source

Effects of Repeated Apomorphine and Haloperidol Treatments on Subsequent Behavioral Sensitivity to Apomorphine

open access: yes, 1989
Effects of repeated apomorphine and haloperidol treatments on subsequent behavioral sensitivity to apomorphine. PHARMACOL BIOCHEM BEHAV 34(2) 345-347, 1989.- In a 2 × 2 factorial design, four groups of rats (n = l0 each) were injected daily with ...
Rowlett, James K., Mattingly, Bruce A.
core  

Sensitization to and conditioning with apomorphine in pigeons

open access: yes, 1989
Pigeons that repeatedly experienced the effect of apomorphine in the same environment showed an augmented behavioural response to the same drug dose as compared with controls that experienced the effect of the drug dose in differing environments ...
Delius, Juan   +3 more
core   +1 more source

Non-Targeted Metabolomics Reveal Apomorphine’s Therapeutic Effects and Lysophospholipid Alterations in Steatohepatitis

open access: yesAntioxidants
Metabolic dysfunction-associated steatohepatitis (MASH), characterized by progressive inflammation and fibrosis, evolves from metabolic dysfunction-associated steatotic liver disease and significantly heightens the risk of cirrhosis and hepatocellular ...
Hideo Ogiso   +4 more
doaj   +1 more source

Effects of Continuous Infusion Therapies on Non-Motor Symptoms in Advanced Parkinson’s Disease: A Systematic Review

open access: yesBrain Sciences
Background/Objectives: Non-motor symptoms (NMS) are highly prevalent in advanced Parkinson’s disease (PD) and substantially affect quality of life. Continuous infusion therapies are established treatment options for motor fluctuations not controlled by ...
Domiziana Rinaldi   +9 more
doaj   +1 more source

Behavioural and neurochemical studies on apomorphine-induced hypomotility in mice

open access: yes, 1981
Small doses of apomorphine (0.075–0.60 μmol/kg), injected subcutaneously into mice, elicited a strong hypomotive response of 20 to 30 min duration. This effect could be inhibited not only by neuroleptics, such as pimozide or sulpiride, but was also ...
Sumners, C.   +2 more
core   +1 more source

Enhancement of transdermal apomorphine delivery with a diester prodrug strategy

open access: yes, 2011
Diester prodrugs of apomorphine, diacetyl apomorphine (DAA), and diisobutyryl apomorphine (DIA), were synthesized, and their partition coefficients, capacity factor (log K'), enzymatic hydrolysis, and in vitro permeation across nude mouse skin were ...
Ming-Chuan Ku   +2 more
core   +1 more source

Apomorphine-induced behavioural sensitization in rats: Individual differences, role of dopamine and NMDA receptors

open access: yes, 1999
Apomorphine-induced behavioural sensitization was studied in male Wistar rats. The acute administration of apomorphine (0.5 mg/kg s.c.), a dopamine agonist, did not affect the locomotor activity of rats, but it caused stereotyped behaviour characterized ...
Volke, V.   +6 more
core  

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