Results 71 to 80 of about 61,321 (225)
Estratégias terapêuticas baseadas na modulação da atividade enzimática das caspases [PDF]
Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências FarmacêuticasA morte celular é um processo geneticamente determinado e importante em organismos ...
Monteiro, Paulo André de Moura
core
Introdução: Estudos in vitro mostram que radioterapia e/ou quimioterapia podem ativar as vias de sinalização do receptor do fator de crescimento epidérmico (EGFR) e Ras, aumentando a resistência cruzada das células de glioblastomas multiformes (GBM) ao ...
Clovis Orlando da Fonseca +9 more
doaj +1 more source
Two water‐soluble polysaccharides were isolated and purified from Tricholoma flavovirens (TF‐P) and Trametes versicolor (TV‐P), respectively. The structures of the two polysaccharides were identified by combining GPC, FT‐IR, HPLC, GC–MS, and NMR, and the structure–activity relationship has also been studied using immune cells and tumor cells. TV‐P with
Zheng‐Ao Sun +5 more
wiley +1 more source
Lichen planus des Ösophagus: Eine prospektive, interdisziplinäre, monozentrische Kohortenstudie [PDF]
Zusammenfassung Hintergrund und Zielsetzung Der Lichen planus (LP) ist eine entzündliche Erkrankung, die Haut, Schleimhäute, sowie Haarfollikel und Nägel betrifft. Die ösophageale Beteiligung ist eine unterschätzte Manifestation. Patienten und Methodik In dieser prospektiven Kohortenstudie (2020–2023) wurden 562 Patienten auf einen symptomatischen und ...
Diehl R +6 more
europepmc +2 more sources
In order to evaluate the effect of hydrocortisone on apoptosis in the jejunum of horses subjected to ischemia and reperfusion, ten horses were paired and grouped into two groups - treated (n=5) and non treated (n=5).
Geraldo Eleno S. Alves +6 more
doaj +1 more source
Regulation der Genexpression von MYCN in humanen Neuoblastomzellen durch Transkriptionsfaktoren der E2F-Familie [PDF]
Seit fast 30 Jahren ist bekannt, dass die Amplifikation und Expression des Onkogens MYCN in Neuroblastomen mit einer sehr ungünstigen Prognose für die Patienten einhergeht.
Eilers, Martin (Prof. Dr.) +1 more
core +1 more source
Perinatale Hirnschäden und Neuroprotektion [PDF]
Perinatal brain damage is a main factor for mortality and long-term morbidity in infants. Several mechanisms have been identified which can lead to perinatal brain injury, such as alterations of oxygen pressure, pharmaceuticals, drugs of abuse, and ...
Koppelstätter, Andrea
core +1 more source
Apoptose e maturação placentária bovina: um estudo imunohistoquímico e morfométrico
Resumo: A liberação da placenta após o parto envolve a perda da adesão materno-fetal e ocorre somente após a maturação completa do placentoma, que está relacionada com a diminuição da celularidade dos tecidos fetal e materno. A apoptose é requerida tanto
Tatiane F. Carvalho +5 more
doaj +1 more source
Mitochondriale Dysfunktion bei Alzheimer-Demenz : das Zusammenspiel von Hirnalterung und genetischen Risikofaktoren [PDF]
Typische neuropathologische Befunde bei der Alzheimer-Demenz (AD) sind die Bildung von Beta-Amyloid-Plaques, die Akkumulation von intrazellulären neurofibrillären Bündeln (Tangles) und ein ausgeprägter Verlust der Nervenzellen im Gehirn (siehe Estifanos ...
Eckert, Gunter P. +2 more
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High expression of anti-apoptotic genes in grade I and II meningiomas
One of the different genetic mechanisms involved in the carcinogenesis of meningiomas is influenced by interactions between proteins that induce and inhibit apoptosis.
Daniela Pretti da Cunha Tirapelli +12 more
doaj +1 more source

