Results 61 to 70 of about 2,457 (179)

Loss of Tripartite Motif–Containing Protein 21 and UVB‐Induced Systemic Inflammation by Regulating DNA‐Sensing Pathways

Arthritis &Rheumatology, Volume 78, Issue 1, Page 172-183, January 2026.
Objective Patients with systemic lupus erythematosus (SLE) experience photosensitivity, with exposure to UVB light driving lupus flares and triggering symptoms like joint pain, fatigue, and cutaneous lesions. Although the mechanism(s) linking UVB exposure to systemic effects are unclear, type I interferons (IFNs) are known to play a role.
Gantsetseg Tumurkhuu, Graziela Perri, Richard Moore, Lihong Huo, Arati Naveen Kumar, Richard Ainsworth, Trinitee Oliver, Gabriela De Los Santos, David Gibb, Jessica Carriere, Jeong Min Yu, Rachel Abuav, Lindsy Forbess, Daniel J. Wallace, Mariko Ishimori, Wonwoo Shon, Christian Stehlik, Caroline A. Jefferies   +17 more
wiley   +1 more source

INDEPENDÊNCIA OU MORTE: A APOPTOSE COMO MECANISMO DE DEFESA

Arquivos de Ciências da Saúde da UNIPAR, 2015
Nas relações desarmônicas, os hospedeiros tendem a selecionar mutações que conferem resistência aos patógenos, enquanto estes selecionam as que neutralizam a resistência. Dessa forma, o processo evolutivo desencadeia nos mais diversificados mecanismos de
Luciano Seraphim Gasques, Paulo Alexandre Galvanini, Fernando Favaretto, Tamara Francislaine Santana, João Alencar Pamphile   +4 more
doaj  

Advancing Mechano‐Bactericidal Surfaces: Mechanisms, Fabrication, and Synergistic Antimicrobial Strategies

Advanced Materials Interfaces, Volume 12, Issue 23, December 8, 2025.
This review provides a detailed introduction to the fabrication and modulation of nanostructured mechano‐bactericidal surfaces and emphasizes integration of photoactive materials, chemical biocides, stimuli‐responsive self‐cleaning coatings, and electro‐mediated strategies to achieve multifunctional and synergistic antimicrobial effects, providing ...
Yiwen Zhong, Yitong Li, Yang Fu, Zhenfang Zhang, Han Lin, Haiyan Li, Xiao‐Bo Chen, Tianyi Ma, Baohua Jia   +8 more
wiley   +1 more source

Attenuation of oxidative stress, inflammation and apoptosis by ethanolic and aqueous extracts of Crocus sativus L. stigma after chronic constriction injury of rats

Anais da Academia Brasileira de Ciências, 2014
In our previous study, the ethanolic and aqueous extracts of Crocus sativus elicited antinociceptive effects in the chronic constriction injury (CCI) model of neuropathic pain. In this study, we explored anti-inflammatory, anti-oxidant and anti-apoptotic
BAHAREH AMIN, KHALIL ABNOUS, VAHIDEH MOTAMEDSHARIATY, HOSSEIN HOSSEINZADEH   +3 more
doaj   +1 more source

Identifizierung eines Moleküls, das den Abbau der aktivierten Checkpoint‐Kinase‐1 auslöst und Charakterisierung der nicht‐katalytischen Funktionen von Checkpoint‐Kinase‐1 in Tumorzellen

Angewandte Chemie, Volume 137, Issue 49, December 1, 2025.
In Tumorzellen führt die durch HU induzierte Verlangsamung der DNA‐Replikation zur Aktivierung von CHK1 durch Autophosphorylierung, was einen Zellzyklusarrest bewirkt und die Rekrutierung des DNA‐Reparaturproteins WRN zur Förderung der DNA‐Reparatur und des Zellüberlebens ermöglicht.
Ramy Ashry, Mohamed Abdelsalam, Julia Hausen, Christoph Hieber, Yanira Zeyn, Anne‐Christin Sarnow, Matthias Schmidt, Sara Najafi, Ina Oehme, Matthias Bros, Jia‐Xuan Chen, Mario Dejung, Wolfgang Sippl, Oliver H. Krämer   +13 more
wiley   +1 more source

Avaliação da terapia com células-tronco mesenquimais halógenas em doença renal crônica de cães e gatos

Pubvet, 2020
A doença renal crônica (DRC), enfermidade caracterizada pela inflamação túbulo-intersticial, atrofia tubular e fi-brose intersticial com perda progressiva da função renal, tem se tornado uma afecção relativamente comum em cães e gatos.
Patricia Furtado Malard, Mauricio Antônio Silva Peixer, Lucas Rodrigues Santana, Bruno Stéfano Lima Dallago, Michele Milistetd, Luis Mauro Queiroz, Hilana dos Santos Sena Brunel   +6 more
doaj   +1 more source

S1‐Leitlinie für bildgebende Diagnostik von Hauterkrankungen

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 12, Page 1616-1632, December 2025.
Zusammenfassung Nichtinvasive Bildgebungstechniken erlauben schnell und schmerzfrei diagnostische Blicke in die Haut, je nach angewandter Methode mit unterschiedlich hoher Auflösung und Eindringtiefe. Schon seit Jahrzehnten aus dem Alltag nicht wegzudenken sind die etablierten Untersuchungsmethoden wie die Dermatoskopie und die hochauflösende ...
Maximilian Deußing, Sandra Schuh, Janis Thamm, Deborah Winkler, Simon Schneider, Teresa Nau, Ulf Darsow, Viktor Schnabel, Martina Ulrich, Lynhda Nguyen, Denis Frenzel, Chiara Fischer, Cristel Ruini, Vasilis Ntziachristos, Martin Kaatz, Hjalmar Kurzen, Bernd Kardorff, Rudolf Herbst, Sonja Grunewald, Elke Sattler, Julia Welzel, Daniela Hartmann   +21 more
wiley   +1 more source

Apoptose na depleção linfocitária induzida pela toxina T-2 em frangos de corte. Histomorfometria da bolsa de Fabricius

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2000
Estudou-se, pela histomorfometria da bolsa de Fabrício, o envolvimento da apoptose como mecanismo de depleção linfocitária em frangos de corte, após ingestão de toxina T-2 de Fusarium sporotrichioides veiculada pela ração.
M.A. Rachid, A.C. Vasconcelos, V.A. Nunes   +2 more
doaj   +1 more source

Induction of ischaemic cardiomyopathy in mice without off‐target effects

Experimental Physiology, Volume 111, Issue 3, Page 598-599, 1 March 2026.
Mark T. Waddingham, James T. Pearson
wiley   +1 more source

Apoptose na modulação da resposta inflamatória aos ovos do Schistosoma mansoni

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2000
Foram estudadas 42 amostras de fígado de camundongos inoculados com cercárias do Schistosoma mansoni, obtidas 40, 60, 80 e 120 dias após a infecção e processadas rotineiramente.
Tristão A.R., Melo A.L., Vasconcelos A.C., Grossi F.M.   +3 more
doaj