Results 41 to 50 of about 69,077 (250)

Pharmacological perspectives from Brazilian Salvia officinalis (Lamiaceae): antioxidant, and antitumor in mammalian cells

open access: yesAnais da Academia Brasileira de Ciências, 2016
Salvia officinalis (Lamiaceae) has been used in south of Brazil as a diary homemade, in food condiment and tea-beverage used for the treatment of several disorders. The objective of this study was to characterize chemical compounds in the hydroalcoholic (
CHARLENE S.C. GARCIA   +9 more
doaj   +1 more source

Effect of linear energy transfer (LET) on complexity of alpha-particle-induced chromosome aberrations in human CD34+ cells. [PDF]

open access: yes, 2007
The aim of this study was to assess the relative influence of linear energy transfer (LET) of α-particles on chromosome aberration complexity in the absence of significant other track structure differences.
Anderson, RM   +5 more
core  

Estresse oxidativo e aumento da apoptose em neutrófilos de cães com azotemia pré-renal

open access: yes, 2013
O presente trabalho tem como objetivo testar a hipotese de que, a semelhanca do que ocorre na uremia, caes com azotemia pre-renal sofrem estresse oxidativo, o qual esta relacionado com alteracoes do metabolismo oxidativo e apoptose dos neutrofilos.
A. C. Silva   +5 more
semanticscholar   +1 more source

Evidenz‐ und konsensbasierte (S3) Leitlinie: Lichen sclerosus

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 4, Page 566-586, April 2026.
Zusammenfassung Die deutschsprachige, konsens‐ und evidenzbasierte S3‐Leitlinie zum Lichen sclerosus (LS) wurde unter Federführung der Deutschen Dermatologischen Gesellschaft e.V. (DDG) und der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe e.V.
Gudula Kirtschig   +25 more
wiley   +1 more source

Leucemia mielóide crônica e o sistema Fas-FasL Chronic myeloid leukemia and the Fas-FasL system

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2005
Com os avanços terapêuticos que incluem o mesilato de imatinibe, o transplante de medula óssea e a infusão de linfócito do doador, a perspectiva de vida dos portadores de leucemia mielóide crônica (LMC) tem aumentado significativamente e a doença pode ...
Ana Paula F. Bergantini   +3 more
doaj   +1 more source

Efeito do Plasma Rico em Plaquetas na apoptose pós-traumática de condrócitos

open access: yes, 2011
OBJECTIVE: To evaluate if the injection of intra-articular platelet-rich plasma (PRP) can reduce impact-induced chondrocyte apoptosis. METHODS: A double-blind experimental study was developed in four knees of two adult rabbits.
M. U. Rezende   +5 more
semanticscholar   +1 more source

Ghrelin protects against cell death in myocardial ischaemia: Emerging role of microRNA

open access: yesExperimental Physiology, Volume 111, Issue 4, Page 1618-1625, 1 April 2026.
Abstract Acute myocardial infarction (MI) accelerates cardiomyocyte apoptosis, which underpins ventricular remodelling and dysfunction. The hormone ghrelin mitigates this remodelling, but the mechanisms remain unclear. Specific microRNAs (miRs) are key modulators and reliable biomarkers of early‐stage apoptosis.
Rajesh Katare   +2 more
wiley   +1 more source

Análise histomorfométrica dos cardiomiócitos e deposição de colágeno no músculo cardíaco de ratas ooforectomizadas

open access: yesPesquisa Veterinária Brasileira, 2016
Resumo: Esse estudo objetivou avaliar o efeito da ooforectomia sob os parâmetros histomorfométricos dos cardiomiócitos e quantificação de colágeno em ratas Wistar. Vinte ratas foram utilizadas e separadas em dois grupos: GI - ooforectomizada e GII - sham-
Maria C.R. Silva   +4 more
doaj   +1 more source

Neuroprotektion und Aktivierung von Neurotrophin-Signaltransduktionswegen durch Hemmung von Protein-Tyrosin-Phosphatasen und durch NO-Donatoren [PDF]

open access: yes, 2004
Trotz des enormen Fortschrittes der Medizin und neuen Erkenntnissen über die pathologischen Mechanismen des neuronalen Zelltodes steht bislang keine wirkungsvolle, kausale Therapie zur Behandlung neurodegenerativer Erkrankungen zur ...
Gerling, Norbert   +1 more
core   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini   +24 more
wiley   +1 more source

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