Salvia officinalis (Lamiaceae) has been used in south of Brazil as a diary homemade, in food condiment and tea-beverage used for the treatment of several disorders. The objective of this study was to characterize chemical compounds in the hydroalcoholic (
CHARLENE S.C. GARCIA +9 more
doaj +1 more source
Effect of linear energy transfer (LET) on complexity of alpha-particle-induced chromosome aberrations in human CD34+ cells. [PDF]
The aim of this study was to assess the relative influence of linear energy transfer (LET) of α-particles on chromosome aberration complexity in the absence of significant other track structure differences.
Anderson, RM +5 more
core
Estresse oxidativo e aumento da apoptose em neutrófilos de cães com azotemia pré-renal
O presente trabalho tem como objetivo testar a hipotese de que, a semelhanca do que ocorre na uremia, caes com azotemia pre-renal sofrem estresse oxidativo, o qual esta relacionado com alteracoes do metabolismo oxidativo e apoptose dos neutrofilos.
A. C. Silva +5 more
semanticscholar +1 more source
Evidenz‐ und konsensbasierte (S3) Leitlinie: Lichen sclerosus
Zusammenfassung Die deutschsprachige, konsens‐ und evidenzbasierte S3‐Leitlinie zum Lichen sclerosus (LS) wurde unter Federführung der Deutschen Dermatologischen Gesellschaft e.V. (DDG) und der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe e.V.
Gudula Kirtschig +25 more
wiley +1 more source
Leucemia mielóide crônica e o sistema Fas-FasL Chronic myeloid leukemia and the Fas-FasL system
Com os avanços terapêuticos que incluem o mesilato de imatinibe, o transplante de medula óssea e a infusão de linfócito do doador, a perspectiva de vida dos portadores de leucemia mielóide crônica (LMC) tem aumentado significativamente e a doença pode ...
Ana Paula F. Bergantini +3 more
doaj +1 more source
Efeito do Plasma Rico em Plaquetas na apoptose pós-traumática de condrócitos
OBJECTIVE: To evaluate if the injection of intra-articular platelet-rich plasma (PRP) can reduce impact-induced chondrocyte apoptosis. METHODS: A double-blind experimental study was developed in four knees of two adult rabbits.
M. U. Rezende +5 more
semanticscholar +1 more source
Ghrelin protects against cell death in myocardial ischaemia: Emerging role of microRNA
Abstract Acute myocardial infarction (MI) accelerates cardiomyocyte apoptosis, which underpins ventricular remodelling and dysfunction. The hormone ghrelin mitigates this remodelling, but the mechanisms remain unclear. Specific microRNAs (miRs) are key modulators and reliable biomarkers of early‐stage apoptosis.
Rajesh Katare +2 more
wiley +1 more source
Resumo: Esse estudo objetivou avaliar o efeito da ooforectomia sob os parâmetros histomorfométricos dos cardiomiócitos e quantificação de colágeno em ratas Wistar. Vinte ratas foram utilizadas e separadas em dois grupos: GI - ooforectomizada e GII - sham-
Maria C.R. Silva +4 more
doaj +1 more source
Neuroprotektion und Aktivierung von Neurotrophin-Signaltransduktionswegen durch Hemmung von Protein-Tyrosin-Phosphatasen und durch NO-Donatoren [PDF]
Trotz des enormen Fortschrittes der Medizin und neuen Erkenntnissen über die pathologischen Mechanismen des neuronalen Zelltodes steht bislang keine wirkungsvolle, kausale Therapie zur Behandlung neurodegenerativer Erkrankungen zur ...
Gerling, Norbert +1 more
core +1 more source
Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini +24 more
wiley +1 more source

