Results 41 to 50 of about 2,457 (179)

Kint3-4 promotes apoptosis and inhibition of angiogenesis in solid Ehrlich Tumor

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2012
A proteína Kint3-4 (PKint3-4), codificadora da angiostatina, é reconhecida por sua potencialidade antiangiogênica. O presente estudo teve como objetivo avaliar o efeito da proteína Kint3-4 no crescimento do tumor sólido de Ehrlich.
C Souza, L.F. Carvalho, M.A.N.D Ferreira, J.L. Pesquero, G.D Cassali   +4 more
doaj   +1 more source

Ghrelin protects against cell death in myocardial ischaemia: Emerging role of microRNA

Experimental Physiology, Volume 111, Issue 4, Page 1618-1625, 1 April 2026.
Abstract Acute myocardial infarction (MI) accelerates cardiomyocyte apoptosis, which underpins ventricular remodelling and dysfunction. The hormone ghrelin mitigates this remodelling, but the mechanisms remain unclear. Specific microRNAs (miRs) are key modulators and reliable biomarkers of early‐stage apoptosis.
Rajesh Katare, Jeffrey R. Erickson, Daryl O. Schwenke   +2 more
wiley   +1 more source

Determination of the minimal representative number of microscopic fields to quantify apoptosis in canine lymph nodes Determinação do número mínimo representativo de campos microscópicos para quantificar apoptose em linfonodos caninos

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2004
Determinou-se o número mínimo de campos por lâmina para se ter uma amostragem representativa para o estudo de apoptose em linfonodos de cães com cinomose.
L. Moro, A.C. Vasconcelos, F.G.A. Santos, C.M. Alves, J.E.S. Nunes, I.B.M. Sampaio   +5 more
doaj   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source

Apoptose e expressão de VP2 e GAPDH na infecção precoce pelo vírus da doença infecciosa da bursa de Fabricius em pintos SPF Apoptosis and expression of VP2 and GADPH in an experimental infectious bursal disease in SPF chicks

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007
Vinte e nove pintos SPF de um dia foram inoculados com o vírus da doença infecciosa da bursa de Fabricius (VDIB) para avaliar a ocorrência precoce de apoptose e a expressão da proteína viral 2 (VP2) e da enzima gliceraldeído fosfato dehidrogenase (GAPDH).
J.J. Batista, A.S. Martins, L. Moro, J.S. Resende, N.R.S. Martins, A.C. Vasconcelos   +5 more
doaj   +1 more source

Pathogenesis of Age‐Related Hearing Loss and Therapeutic Strategies

Sensory Neuroscience, Volume 2, Issue 1, March 2026.
ABSTRACT Age‐related hearing loss (ARHL) is a degenerative disorder of the auditory system, characterized by bilateral symmetrical sensorineural hearing loss that occurs with aging. As a highly prevalent age‐related condition worldwide, ARHL significantly impairs both the quality of life and mental health of the elderly.
Yu Xiao, Jiaxin Liu, Xiaohan Zhang, Miao Chang, Cheng Cheng, Yunhao Wu, Xiaolong Fu   +6 more
wiley   +1 more source

Efeitos da isquemia e da reperfusão na ocorrência de apoptose no jejuno em eqüinos Effects of ischemia and reperfusion in apoptosis occurrence in equine jejunum

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007
Investigou-se o resultado da isquemia, da congestão e da reperfusão na ocorrência de apoptose. Modelos de obstrução vascular total - artériovenosa e venosa - foram induzidos no jejuno por 2h, seguidos de reperfusão durante 12h.
J.M.G. Abreu, G.E.S. Alves, A.C. Vasconcelos, J.D. Ribeiro Filho, R.R. Faleiros   +4 more
doaj   +1 more source

ZFP36 inhibits the pro‐apoptotic effects of transforming growth factor β1 on mitral valve interstitial cells via the GTP‐binding protein 6 pathway in mitral valve prolapse

Experimental Physiology, Volume 111, Issue 3, Page 700-713, 1 March 2026.
Abstract The objective of this work was to investigate the role of ZFP36 in mitral valve prolapse (MVP). Mitral valve and plasma were collected to assess the expression of ZFP36, transforming growth factor β (TGF‐β), collagen and elastin and apoptosis rates.
Meng Zhao, Zhaoyi Zhu, Yawei Dai, Li Jiang, Qihan Wen, Yingjie Zhang, Qingyang Shi, Yihu Tang, Jingxin Zhou, Yanhu Wu   +9 more
wiley   +1 more source

Porcentagem de parênquima e índice apoptótico da bolsa cloacal em frangos de corte em ambiente de conforto e estresse térmico

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2003
Noventa e seis pintos de corte foram mantidos em diferentes temperaturas ambientais (calor, 29ºC; neutro, 24ºC; frio, 15ºC) e oito aves de cada grupo de temperatura (tratamento) foram sacrificadas nos dias 1, 7, 14, 21, 28, 35 e 42, e suas bolsas ...
E.B. Guimarães, A.C. Vasconcelos, N.R.S. Martins, R.F.M. Oliveira, L. Moro, J.E.S. Nunes, F.G.A. Santos   +6 more
doaj   +1 more source

Novel Glycyrrhizinic Acid Derivative YCY‐20 Inhibits Cerebral Ischemia/Reperfusion Induced Apoptosis via the AGE‐RAGE/MAPK Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
Novel licorice‐derived compound YCY‐20 attenuates cerebral ischemia–reperfusion injury by suppressing neuronal apoptosis. Mechanistic studies reveal its neuroprotection is mediated through inhibition of the AGE‐RAGE/MAPK pathway, providing a preclinical foundation for stroke therapeutics development.
Jia Luo, Xue Qin, Jiaxin Chen, Xiushi Yu, Ziyun Liu, Jiyi Lv, Xinhui Pan, Yong Chen, Lili Wei   +8 more
wiley   +1 more source