Results 71 to 80 of about 22,852 (212)

Apoptose em pólipos nasais eosinofílicos submetidos in vitro ao tratamento com mitomicina C Apoptosis in eosinophilic nasal polyps treated in vitro with mitomycin C

Brazilian Journal of Otorhinolaryngology, 2012
A etiopatogênese da polipose nasal eosinofílica ainda não foi esclarecida. Os eosinófilos constituem as principais células do infiltrado inflamatório e estão relacionados com a perpetuação do processo inflamatório na rinossinusite crônica com pólipos ...
Cláudia Pena Galvão dos Anjos, Anilton Cesar Vasconcelos, Paulo Fernando Tormin Borges Crosara, Gustavo Coelho dos Anjos, Celso Gonçalves Becker, Roberto Eustáquio Santos Guimarães   +5 more
doaj   +1 more source

Avaliação da terapia com células-tronco mesenquimais halógenas em doença renal crônica de cães e gatos

Pubvet, 2020
A doença renal crônica (DRC), enfermidade caracterizada pela inflamação túbulo-intersticial, atrofia tubular e fi-brose intersticial com perda progressiva da função renal, tem se tornado uma afecção relativamente comum em cães e gatos.
Patricia Furtado Malard, Mauricio Antônio Silva Peixer, Lucas Rodrigues Santana, Bruno Stéfano Lima Dallago, Michele Milistetd, Luis Mauro Queiroz, Hilana dos Santos Sena Brunel   +6 more
doaj   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source

Apoptose na modulação da resposta inflamatória aos ovos do Schistosoma mansoni

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2000
Foram estudadas 42 amostras de fígado de camundongos inoculados com cercárias do Schistosoma mansoni, obtidas 40, 60, 80 e 120 dias após a infecção e processadas rotineiramente.
Tristão A.R., Melo A.L., Vasconcelos A.C., Grossi F.M.   +3 more
doaj  

Attenuation of oxidative stress, inflammation and apoptosis by ethanolic and aqueous extracts of Crocus sativus L. stigma after chronic constriction injury of rats

Anais da Academia Brasileira de Ciências, 2014
In our previous study, the ethanolic and aqueous extracts of Crocus sativus elicited antinociceptive effects in the chronic constriction injury (CCI) model of neuropathic pain. In this study, we explored anti-inflammatory, anti-oxidant and anti-apoptotic
BAHAREH AMIN, KHALIL ABNOUS, VAHIDEH MOTAMEDSHARIATY, HOSSEIN HOSSEINZADEH   +3 more
doaj   +1 more source

Biochemical evaluation of focal non-reperfusion cerebral ischemia by middle cerebral artery occlusion in rats Avaliação bioquímica da isquemia cerebral focal, não associada à reperfusão, por oclusão da artéria cerebral média em ratos

Arquivos de Neuro-Psiquiatria, 2008
Cerebral ischemia is an important event in clinical and surgical neurological practice since it is one of the diseases that most compromise the human species. In the present study 40 adult rats were submitted to periods of focal ischemia of 30, 60 and 90
Benedicto Oscar Colli, Daniela Pretti da Cunha Tirapelli, Carlos Gilberto Carlotti Jr, Luiza da Silva Lopes, Luis Fernando Tirapelli   +4 more
doaj   +1 more source

Die Bedeutung der MAP-Kinasen in der monomer-induzierten Apoptose [PDF]

, 2016
Dentale Kunststoffe treten in direkten Kontakt mit humanen Geweben, insbesondere in tiefen Kavitäten mit dünner bis nicht mehr vorhandener Restdentinschicht mit der Zahnpulpa. Die direkte und indirekte Wirkung der enthaltenen Monomere auf die Pulpazellen
Klement, Johannes Maximilian
core   +1 more source

Bothrops alternatus snake venom induces apoptosis of skeletal muscle cells in a rabbit model

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
RESUMO Este estudo objetiva reportar a ocorrência de apoptose in vivo induzida pelo veneno da serpente Bothrops alternatus em células musculares esqueléticas.
W.G. Santos, T.L. Silveira, A.T.L. Fiúza, A.F.M. Botelho, I.N.N. Gonçalves, E. Ferreira, B. Soto-Blanco, M.M. Melo   +7 more
doaj   +1 more source

Calcium and cell death signaling in neurodegeneration and aging

Anais da Academia Brasileira de Ciências, 2009
Transient increase in cytosolic (Cac2+) and mitochondrial Ca2+ (Ca m2+) are essential elements in the control of many physiological processes. However, sustained increases in Ca c2+ and Ca m2+ may contribute to oxidative stress and cell death.
Soraya Smaili, Hanako Hirata, Rodrigo Ureshino, Priscila T. Monteforte, Ana P. Morales, Mari L. Muler, Juliana Terashima, Karen Oseki, Tatiana R. Rosenstock, Guiomar S. Lopes, Claudia Bincoletto   +10 more
doaj   +1 more source

Modulatory effects of rutin on biochemical and hematological parameters in hypercholesterolemic Golden Syrian hamsters

Anais da Academia Brasileira de Ciências, 2009
Flavonoids have been reported to exhibit several pharmacological properties, mainly in cardiovascular and inflammatory diseases. In the present study, we observed that rutin, a known glycosylated flavonoid isolated from Dimorphandra mollis, had a ...
Alexandre Kanashiro, Daiani C.O. Andrade, Luciana M. Kabeya, Walter M. Turato, Lucia H. Faccioli, Sérgio A. Uyemura, Yara M. Lucisano-Valim   +6 more
doaj   +1 more source