Results 71 to 80 of about 69,077 (250)

Estratégias terapêuticas baseadas na modulação da atividade enzimática das caspases [PDF]

, 2014
Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências FarmacêuticasA morte celular é um processo geneticamente determinado e importante em organismos ...
Monteiro, Paulo André de Moura
core  

Loss of Tripartite Motif–Containing Protein 21 and UVB‐Induced Systemic Inflammation by Regulating DNA‐Sensing Pathways

Arthritis &Rheumatology, Volume 78, Issue 1, Page 172-183, January 2026.
Objective Patients with systemic lupus erythematosus (SLE) experience photosensitivity, with exposure to UVB light driving lupus flares and triggering symptoms like joint pain, fatigue, and cutaneous lesions. Although the mechanism(s) linking UVB exposure to systemic effects are unclear, type I interferons (IFNs) are known to play a role.
Gantsetseg Tumurkhuu, Graziela Perri, Richard Moore, Lihong Huo, Arati Naveen Kumar, Richard Ainsworth, Trinitee Oliver, Gabriela De Los Santos, David Gibb, Jessica Carriere, Jeong Min Yu, Rachel Abuav, Lindsy Forbess, Daniel J. Wallace, Mariko Ishimori, Wonwoo Shon, Christian Stehlik, Caroline A. Jefferies   +17 more
wiley   +1 more source

Ouabain exacerbates activation-induced cell death in human peripheral blood lymphocytes

Anais da Academia Brasileira de Ciências, 2005
Lymphocytes activated by mitogenic lectins display changes in transmembrane potential, an elevation in the cytoplasmic Ca2+ concentrations, proliferation and/or activation induced cell death.
Mabel B. Esteves, Luis F. Marques-Santos, Ottília R. Affonso-Mitidieri, Vivian M. Rumjanek   +3 more
doaj   +1 more source

Advancing Mechano‐Bactericidal Surfaces: Mechanisms, Fabrication, and Synergistic Antimicrobial Strategies

Advanced Materials Interfaces, Volume 12, Issue 23, December 8, 2025.
This review provides a detailed introduction to the fabrication and modulation of nanostructured mechano‐bactericidal surfaces and emphasizes integration of photoactive materials, chemical biocides, stimuli‐responsive self‐cleaning coatings, and electro‐mediated strategies to achieve multifunctional and synergistic antimicrobial effects, providing ...
Yiwen Zhong, Yitong Li, Yang Fu, Zhenfang Zhang, Han Lin, Haiyan Li, Xiao‐Bo Chen, Tianyi Ma, Baohua Jia   +8 more
wiley   +1 more source

Effects of Panax ginseng, Turnera diffusa and Heteropterys tomentosa extracts on hippocampal apoptosis of aged rats

Einstein (São Paulo)
OBJECTIVE: To verify if the medicinal plants Panax ginseng C.A. Mey, Turnera diffusa Willd. ex Schult., and Heteropterys tomentosa O. Mach., which are amply used by the population as tonics and cognition enhancers, could have a protective effect on cell ...
Andréia Gomes Bezerra, Soraya Soubhi Smaili, Guiomar Silva Lopes, Elisaldo Araújo Carlini   +3 more
doaj   +1 more source

Apoptose em pólipos nasais eosinofílicos submetidos in vitro ao tratamento com mitomicina C Apoptosis in eosinophilic nasal polyps treated in vitro with mitomycin C

Brazilian Journal of Otorhinolaryngology, 2012
A etiopatogênese da polipose nasal eosinofílica ainda não foi esclarecida. Os eosinófilos constituem as principais células do infiltrado inflamatório e estão relacionados com a perpetuação do processo inflamatório na rinossinusite crônica com pólipos ...
Cláudia Pena Galvão dos Anjos, Anilton Cesar Vasconcelos, Paulo Fernando Tormin Borges Crosara, Gustavo Coelho dos Anjos, Celso Gonçalves Becker, Roberto Eustáquio Santos Guimarães   +5 more
doaj   +1 more source

Produção da proteína recombinante anexina V humana em cultivos de Escherichia coli em batelada alimentada [PDF]

, 2013
Annexin V is an endogenous human protein Ca+2 dependent, with a molecular weight of 35. 8 kDa, widely distributed intracellularly, with very high concentrations in the placenta and lower concentrations in endothelial cells, kidneys, myocardium, skeletal ...
Marder, Laura Schirmbeck
core  

Apoptose e sua importancia no curso da infecção pelo Trypanosoma cruzi

, 2011
Na presente revisao procurou-se focalizar a participacaoo da apoptose nos mecanismos patogenicos e na patologia da doenca de Chagas. A apoptose se constitui em importante capitulo da Patologia Geral e pode ser definida como uma "morte celular programada",
S. Andrade
semanticscholar   +1 more source

Identifizierung eines Moleküls, das den Abbau der aktivierten Checkpoint‐Kinase‐1 auslöst und Charakterisierung der nicht‐katalytischen Funktionen von Checkpoint‐Kinase‐1 in Tumorzellen

Angewandte Chemie, Volume 137, Issue 49, December 1, 2025.
In Tumorzellen führt die durch HU induzierte Verlangsamung der DNA‐Replikation zur Aktivierung von CHK1 durch Autophosphorylierung, was einen Zellzyklusarrest bewirkt und die Rekrutierung des DNA‐Reparaturproteins WRN zur Förderung der DNA‐Reparatur und des Zellüberlebens ermöglicht.
Ramy Ashry, Mohamed Abdelsalam, Julia Hausen, Christoph Hieber, Yanira Zeyn, Anne‐Christin Sarnow, Matthias Schmidt, Sara Najafi, Ina Oehme, Matthias Bros, Jia‐Xuan Chen, Mario Dejung, Wolfgang Sippl, Oliver H. Krämer   +13 more
wiley   +1 more source

Do yeast apoptose?

The Journal of Cell Biology, 2004
![][1] Dead cells bind dye nonspecifically. Suicide in a unicellular organism might sound like a lousy idea, but there are several possible justifications. Budding yeast cells that are sickly, mating-incompetent, or stuck in the middle of a colony might do better to go out with ...
openaire   +2 more sources