Results 161 to 170 of about 1,019,500 (194)

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Functional Role of NOXA in Hypoxia-Mediated PD-L1 Inhibitor Response in Hepatocellular Carcinoma. [PDF]

Int J Mol Sci
Huang M, Lan T, Chen X, Chen R, Ding X, Tai WC, Wong SC, Chan LW.   +7 more
europepmc   +1 more source

Engineered 3D Kidney Glomerular Microtissues to Model Podocyte‐Centric Diseases for the Validation of New Drug Targets

Advanced Healthcare Materials, EarlyView.
The study introduces innovative 3D microtissues that replicate the glomerular filtration barrier of the kidney, offering a novel platform for understanding podocytopathies. These microtissues simulate the glomerulus's structure and dynamics, allowing for the modeling of podocyte injuries and drug testing.
Sara Buttό, Solange Vidal, Xi Rui Zeng, Martin Rausch, Immihan Ceren Yasa, Magali P. Ferro   +5 more
wiley   +1 more source

Deep transfer learning approach for automated cell death classification reveals novel ferroptosis-inducing agents in subsets of B-ALL. [PDF]

Cell Death Dis
Stachura P, Lu Z, Kronberg RM, Xu HC, Liu W, Tu JW, Schaal K, Kameri E, Picard D, von Karstedt S, Fischer U, Bhatia S, Lang PA, Borkhardt A, Pandyra AA.   +14 more
europepmc   +1 more source

Study on the regulation of renal tubular cell apoptosis by SIRT1/NF-κB signaling pathway in septic acute kidney injury. [PDF]

Ren Fail
Chu W, Sun X, Yan Y.
europepmc   +1 more source

Chemical profiling and anticancer activity of Alnus incana dichloromethane fraction on HeLa cells via cell cycle arrest and apoptosis. [PDF]

BMC Complement Med Ther
Hesham W, Elzayat EM, Hosney M, Abo-Elghiet F.   +3 more
europepmc   +1 more source

Therapeutic Potential of Quadrigemine I Against Lymphoma: Mechanistic Insights from Cell Lines and Xenograft Models Demonstrating DNA Damage, Oxidative Stress, and Pathway Regulation. [PDF]

Int J Mol Sci
Pu J, Shi W, Cui J, Yang H, Cao J, Liu Y, Xiao S, Cheng G.   +7 more
europepmc   +1 more source

Interleukin-37 mediates the anti-oral tumor activity in oral cancer through STAT3. [PDF]

Open Med (Wars)
Fang J, Li K, Zhang L, Zhang Y, Wang Y, Zhang J.   +5 more
europepmc   +1 more source

MiR-27b-3p Reduces the Efficacy of Propranolol in the Treatment of Infantile Hemangioma by Inhibiting the Expression of Apaf-1. [PDF]

Biomedicines
Li J, Zhu Y, Xie L, Ahmadi S, Yao C, Cui H, Kang X, Tu J, Na S.   +8 more
europepmc   +1 more source