Results 21 to 30 of about 103 (94)

The role of oxidative stress, apoptosis and altered TRPM2 channel activation in doxorubicin-induced liver injury; the protective effect of selenium

Acta Medica Alanya
Aim: Doxorubicin (DOXR) is frequently used alone or as combination therapy in the treatment of various types of cancer. Although dose-dependent side effects are known, its effects on liver health are not fully known.
Mehmet Hafit Bayir, Fikret Altındağ, Zübeyir Huyut, Kenan Yıldızhan   +3 more
doaj   +1 more source

Association Between Anti-Proliferative Activity of Evernia Prunastri with the Cellular Apoptotic Pathway

Cumhuriyet Science Journal, 2017
Evernia prunastri (L.) Ach, belonging to Parmeliaceae, is animportant lichen species in Turkey. Previous studies was reported that E.
Önder Yumrutaş, Celal Güven, Yusuf Özay, İşıl Albeniz, Müfide Aydoğan Ahbab, İbrahim Bozgeyik, Atilla Yıldız, Haydar Bağış, Leyla Türker Şener   +8 more
doaj   +1 more source

KML VE KML LÖSEMİK KÖK HÜCRESİ ARASINDA MİKRORNA EKSPRESYON DEĞİŞİMLERİNİN DEĞERLENDİRİLMESİ

Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi, 2020
Amaç:Kronik Miyeloid Lösemi (KML), hematopoetik kök hücreden (HKH) köken alan miyeloproliferatifbir hastalıktır. MikroRNA'lar, transkripsiyonsonrası gen ekspresyonunu düzenlenleyen küçük kodlamayan RNA’lardır.
Melek Pehlivan, Mustafa Soyöz, Hatice İlayhan Karahan Çöven, Burcu Çerçi, Tülay Kılıçaslan Ayna, Halil Ateş, Zeynep Yüce, Hakkı Ogün Sercan   +7 more
doaj   +1 more source

Investigation of the effects of chrysin on intestinal ischemia-reperfusion via apoptotic, oxidative stress, inflammation, and autophagy parameters

Laboratuvar Hayvanları Bilimi ve Uygulamaları Dergisi
Aim: This study aimed to investigate chrysin's molecular, biochemical, and histological effects in an experimental intestinal ischemia/reperfusion (IR) model and to reveal possible protective mechanisms.Material-Methods: 35 Wistar rats were randomly ...
Fatih Mehmet Kandemir, Ayşe Betül Öztürk, Hasan Şimşek, Nurhan Akaras   +3 more
doaj   +1 more source

Assessment of Anticancer Properties of Synthesized Pyrazole-Acridine Derivative on SH-SY5Y Human Neuroblastoma Cells

Düzce Tıp Fakültesi Dergisi
Aim: This study aimed to synthesize a novel pyrazole acridine derivative (3-ACH) and evaluate its anticancer properties on SH-SY5Y human neuroblastoma cells.Material and Methods: The pyrazole-4-carbaldehyde derivative was cyclized with dimedone and p ...
Muna Elmusa, Mohammadreza Dastourı, Rahmi Kasımoğulları, Hümeyra Yılmaz, Fatıma Elmusa, Yusuf Küçükbağrıaçık   +5 more
doaj   +1 more source

Protective Potential of Morin in Ifosfamide-Induced Lung Toxicity: Modulation of Oxidative Stress, Inflammation and Apoptosis Parameters

Veterinary Sciences and Practices
In this study, the protective effect of morin against lung toxicity induced by ifosfamide (IFO), a widely used drug in cancer treatment, was investigated. Thirty-five male Sprague Dawley rats were divided into five groups: Control, Morin (200 mg/kg), IFO
Elif Dalkılınç, Özge Kandemir
doaj   +1 more source

Apoptoz v razvitii remissiisakharnogo diabeta 1 tipa

Сахарный диабет, 2006
Цель. Изучение иммунологических параметров лимфоидных клеток крови у пациентов с впервые выявленным сахарным диабетом, в том числе Fas-рецептора програмированный гибели клеток (СД 95). Материалы и методы.
Tatiana Vasil'evna Nikonova, Sergey Alexandrovich Prokof'ev, Vera Anatol'evna Gorelysheva, Olga Mikhailovna Smirnova, Svetlana Mikhailovna Stepanova, L P Alekseev   +5 more
doaj   +1 more source

Investigation of the effects of Protocatechuic acid on apoptosis, oxidant and antioxidant status in Caco-2 colorectal cancer cells

Acta Medica Alanya
Aim: Protocatechuic acid (PCA) is one of the common phenolic acids found in many foods and plants and it has multiple biological activities. Although PCA has been investigated for its antioxidant, anti-inflammatory, and anticancer effects in various cell
Fatma Yıldız
doaj   +1 more source

Elucidating the Molecular Mechanism by Which Gallic Acid Alleviates Oxidative Stress and Inflammatory Response of Acrylamide-Induced Renal Injury in a Rat Model

Veterinary Sciences and Practices
This study investigates the molecular effects of Acrylamide (ACR)-induced kidney damage and the potential protective role of Gallic acid (GA). Forty male rats were divided into five groups: Control, ACR, ACR+GA50, ACR+GA100, and GA100.
Samet Tekin
doaj   +1 more source

Diyabette Leptin Hormonun Olası Etkileri

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2019
Şekerhastalığı olarak bilinen diyabet, çeşitli komplikasyonları (kalp ve dolaşımhastalıkları, kanser ve buna benzer hastalıklar) beraberinde getiren, insanhayatını olumsuz yönde etkileyen metabolik bir hastalıktır.
Eylem Taşkın Güven, Celal Güven, Salih Tunç Kaya, Yusuf Sevgiler   +3 more
doaj   +1 more source