Results 51 to 60 of about 991,351 (253)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Entanglement of Nature Worshippers From Posočje With Stones
Acta HistriaeThis article argues that the beliefs and belief system of nature worshippers from Posočje differ significantly from the Greco-Roman or Judeo-Christian hierarchical anthropocentric perspectives, which classify the ecosphere according to its usefulness ...
Polona TRATNIK
doaj +1 more source
Проблеми Законності, 2014 The article is devoted to the research of the information function realization by the Verkhovna Rada of Ukraine apparatus as a component in the system of it constitutional-legal status with the use of the applied knowledges of the information law ...
Н. С. Погребняк
doaj +1 more source
Numerical study of a flow in the cerebral arterial circle [PDF]
Computer Methods in Materials Science, 2009 Blood is supplied to the brain by two internal carotid and two vertebral arteries. These arteries join to form the cerebral arterial circle (also called the Circle of Willis or the CoW).
Damian Obidowski +2 more
doaj +1 more source
The Apparatus of Social Reproduction: Uncovering the Work Functions of Transgender Women
, 2018 The apparatus of social reproduction describes the process by which knowledge production contributes to oppressive conditions. This article explains and defines this process through the application of a critical theoretical lens informed the Foucauldian ...
Lane, William A., Seelman, Kristie L.
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The evolution of the parliamentary apparatus in Ukraine.
Теорія і практика правознавства, 2016 The basic stages, features and problems of the evolution of the Apparatus of the Parliament in Ukraine have been investigated in the article. The trends and patterns of changes of it status on different stages of the development were identified.
Н. С. Погребняк
doaj +1 more source
Numerical analysis of an influence of the artificial valve type on the blood flow inside the ventricular assist device [PDF]
Computer Methods in Materials Science, 2011 A Ventricular Assist Device (VAD) is used in case of severe heart illnesses when the natural heart supplies the body with an insufficient volume of blood. Any damage or improper functioning of the VAD can result in the patient’s death.
Przemyslaw Klosinski +3 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source