Results 71 to 80 of about 715,743 (303)

Enhancing Small Molecule Sensing With Aptameric Functionalized Nano Devices

Advanced Materials Technologies, EarlyView.
Unveiling an ultra‐sensitive, non‐invasive neurotransmitter sensor. For the first time, a nanoscale sensor for detecting an important neurotransmitter was demonstrated using micro‐electromechanical systems (MEMS) technology. Our approach utilized field‐effect transistor (FET)‐based readout to enable pico‐molar detection of biomarkers in sweat.
Thi Thanh Ha Nguyen, Cong Minh Nguyen, Quang Thang Trinh, Minh Anh Huynh, Khanh Vinh Ho, Dang Co Pham, Dzung Dao, Sven Ingebrandt, Sina Jamali, Xuan Thang Vu, Nam‐Trung Nguyen, Tuan‐Khoa Nguyen   +11 more
wiley   +1 more source

A bidirectional network for appetite control in larval zebrafish

eLife, 2019
Medial and lateral hypothalamic loci are known to suppress and enhance appetite, respectively, but the dynamics and functional significance of their interaction have yet to be explored.
Caroline Lei Wee, Erin Yue Song, Robert Evan Johnson, Deepak Ailani, Owen Randlett, Ji-Yoon Kim, Maxim Nikitchenko, Armin Bahl, Chao-Tsung Yang, Misha B Ahrens, Koichi Kawakami, Florian Engert, Sam Kunes   +12 more
doaj   +1 more source

Differential Roles of Two Leptin Gene Paralogues on Food Intake and Hepatic Metabolism Regulation in Mandarin Fish

Frontiers in Endocrinology, 2020
Leptin affects food intake regulation and energy homeostasis in mammals, as opposed to mammals who have a single leptin gene, fish have duplicated leptin gene paralogues.
Xiao-Chen Yuan, Xiao-Chen Yuan, Xu-Fang Liang, Xu-Fang Liang, Wen-Jing Cai, Wen-Jing Cai, Ai-Xuan Li, Ai-Xuan Li, Dong Huang, Dong Huang, Shan He, Shan He   +11 more
doaj   +1 more source

Effects of repeated consumption on sensory-enhanced satiety [PDF]

, 2014
Previous research suggests that sensory characteristics of a drink modify the acute satiating effects of its nutrients, with enhanced satiety evident when a high energy drink was thicker and tasted creamier.
Booth, de Graaf, Jeffrey M. Brunstrom, Keri McCrickerd, Lucy Chambers, Martin R. Yeomans   +5 more
core   +1 more source

Hepatocyte PIEZO1 Negatively Regulates Lipogenesis and Ameliorates MASLD by Sensing Membrane Tension and Activating AMPK

Advanced Science, EarlyView.
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen, Qimeng Wang, Ke Yang, Qinghai Lian, Xuyun Peng, Zhiyong Gong, Xinyi Zhao, Yong Wu, Tian Tao, Siqi Xu, Yifan Chen, Xiaoyan Tang, Jinghui Guo, Geyang Xu, Qi Zhang   +14 more
wiley   +1 more source

A magnetic resonance imaging and gut flora-based study of intake desire in overweight/obese type 2 diabetes mellitus patients

Frontiers in Neuroscience
BackgroundAbnormal regulation of food intake in overweight/obese type 2 diabetes mellitus (T2DM) patients is an important cause of energy intake imbalance, and studies have demonstrated that the “gut-brain axis” is involved in a wide range of metabolic ...
Mingxuan Gao, Liya Gong, Yanmei Zeng, Dongling Li, Junyan Wen, Ying Guo, Zhujia Li, Jingwen Luo, Chunling Chen, Ge Wen   +9 more
doaj   +1 more source

Rumour Processes on N [PDF]

, 2010
We study four discrete time stochastic systems on $\bbN$ modeling processes of rumour spreading. The involved individuals can either have an active or a passive role, speaking up or asking for the rumour.
Bonar, Feller, Fort, Fábio P. Machado, Kurtz, Lebensztayn, Maki, Mauricio Zuluaga, Valdivino V. Junior   +8 more
core   +1 more source

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

Advanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang, Hongyi Zhang, Haixiang Guo, Xiwen Zhang, Yidan Wang, Baoyin Wang, Tong Wang, Guokun Zhao, Qing Zhang, Fei Gao, Shuang Liang, Hao Jiang, Yu Ding, Xiliang Du, Jiabao Zhang, Yi Zheng, Xinwei Li, Bao Yuan   +17 more
wiley   +1 more source

Effectiveness of an innovative oral hygiene product in patients with obesity and type 2 diabetes mellitus in regulating appetite and food preferences

Consilium Medicum
Background. Diabetes mellitus (DM) and obesity are diseases that lead to systemic complications that shorten life expectancy and reduce quality of life. Treatment and control of these diseases can reduce the risk of complications.
Fatima K. Dzgoeva, Elena A. Karton, Irina G. Ostrovskaya, Ekaterina A. Shestakova, Anastasiia V. Anokhina, Marina V. Shestakova   +5 more
doaj   +1 more source

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source