Results 91 to 100 of about 196,133 (310)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
, 2003 The problem of Small Area Estimation is how to produce reliable estimates of area (domain) characteristics, when the sizes within the areas are too small to warrant the use of traditional direct survey estimates.
Pfeffermann, Danny, Tiller, Richard
core
Evolving graphs: dynamical models, inverse problems and propagation [PDF]
, 2009 Applications such as neuroscience, telecommunication, online social networking, transport and retail trading give rise to connectivity patterns that change over time.
Higham, Desmond J +4 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Gaussian Tests of "Extremal White Noise" for Dependent, Heterogeneous, Heavy Tailed Strochastic Processes with an Application [PDF]
We develop a non-parametric test of tail-specific extremal serial dependence for possibly heavy-tailed time series. The test statistic is asymptotically chi-squared under a null of "extremal white noise", as long as extremes of the time series are Near ...
Jonathan B. Hill
core
npj Computational MaterialsModifying solution viscosity is a key functional application of polymers, yet the interplay of molecular chemistry, polymer architecture, and intermolecular interactions makes tailoring precise rheological responses challenging.
Shengli Jiang, Michael A. Webb
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
FORMALIZATION OF THE VIRTUAL EVALUATION OF STRAIN INTENSITY IN SPDed COMMERCIALLY PURE COPPER BILLET
Acta Metallurgica Slovaca, 2014 This work presented the results of solution of the strain intensity evolution in a commercially pure copper billet in the process of severe plastic deformation (SPD) by equal channel angular pressing (ECAP) technique.
Song-Jeng Huan +3 more
doaj +1 more source
International Journal of Statistics and Probability, 2017 This paper provides a complete proof of the strong convergence of the Jump adapted discretization Scheme in the univariate and mark independent jump diffusion process case. We put in detail and clearly a known and general result for mark dependent jump diffusion process. A Monte-Carlo simulation is used as well to show numerical evidence.
Renaud Fadonougbo, George O. Orwa
openaire +2 more sources
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source