Results 71 to 80 of about 1,271,540 (296)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Physical Pictures of Transport in Heterogeneous Media: Advection-Dispersion, Random Walk and Fractional Derivative Formulations

, 2002
The basic conceptual picture and theoretical basis for development of transport equations in porous media are examined. The general form of the governing equations is derived for conservative chemical transport in heterogeneous geological formations, for
Anderson, Bear, Berkowitz, Berkowitz, Berkowitz, Berkowitz, Berkowitz, Berkowitz, Bouchaud, Brian Berkowitz, Chandrasekhar, Compte, Compte, Compte, Compte, Cushman, Dagan, Deng, Eggleston, Feehley, Garabedian, Gelhar, Glimm, Gnedenko, Haggerty, Harvey, Harvey Scher, Hatano, Hilfer, Jespersen, Joseph Klafter, Kenkre, Kinzelbach, Klafter, Klafter, Klafter, Koltermann, Kosakowski, Labolle, Labolle, Li, Lévy, Lévy, Mantegna, Mantegna, Margolin, Margolin, Matheron, Metzler, Metzler, Metzler, Metzler, Neuman, Oldham, Oppenheim, Ralf Metzler, Rubin, Samko, Scheidegger, Scheidegger, Scher, Scher, Scher, Shlesinger, Shlesinger, Silliman, Sposito, Zhang, Zumofen   +68 more
core   +1 more source

Non-Stationary Dependence Structures for Spatial Extremes [PDF]

, 2016
Max-stable processes are natural models for spatial extremes because they provide suitable asymptotic approximations to the distribution of maxima of random fields. In the recent past, several parametric families of stationary max-stable models have been
Genton, Marc G., Huser, Raphael
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Electrochemical performance study of Ag/AgCl and Au flexible electrodes for unobtrusive monitoring of human biopotentials

Nano Select, 2022
Flexible and stretchable electronics are a logical choice for the recording of biopotentials, due to their improved patient comfort and customizability. There is, however, significant variance in the signal quality received from these electrodes based on
Jonas F. Kurniawan, Alexis B. Allegra, Timothy Pham, Andrew K. L. Nguyen, Nathan L. J. Sit, Boris Tjhia, Andrew J. Shin, Todd P. Coleman   +7 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

An Analytical Formula for the Transition Density of a Conic Combination of Independent Squared Bessel Processes with Time-Dependent Dimensions and Financial Applications

Mathematics
The squared Bessel process plays a central role in stochastic analysis, with broad applications in mathematical finance, physics, and probability theory.
Nopporn Thamrongrat, Chhaunny Chhum, Sanae Rujivan, Boualem Djehiche   +3 more
doaj   +1 more source

Felt Accountability and Managerial Performance: The Moderation Effects of Organizational Commitment and Work Motivation (Empirical Study on Medical Managers of Community Health Centers in Pemalang Regency) [PDF]

SHS Web of Conferences
This research aims to scrutinize the effect of felt accountability on managerial performance with organizational commitment and work motivation as moderating variables.
Munasifa Naelal, Pratolo Suryo
doaj   +1 more source