Results 121 to 130 of about 178,018,163 (293)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
User, and Open Collaborative Innovation: Ascendent Economic Models [PDF]
In this paper we assess the economic viability of innovation by producers relative to two increasingly important alternative models: innovations by single user individuals or firms, and open collaborative innovation projects.
Eric von Hippel, Carliss Y. Baldwin
core
Journal of Open Innovation: Technology, Market and ComplexityThe nature of emergent economies presents high complexity in the marketplace, where institutional voids hinder technology adoption and constrain innovation. Despite the acknowledged role of Open Innovation (OI) in driving economic growth, research on its
Konrawan Rattanaburi +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
A Study of The Influence on Applying Open Innovation to Customer Service Satisfaction
, 2010 [[abstract]]With global economy rapidly developing in recent years, enterprises have constantly adjusted their business strategies accordingly. As enterprises used to operate businesses closed-internally, they have made a little connection with external ...
Chiang Wan Ju
core
TCT innovation taxonomy and open foresight innovation paradigm
This paper presents a novel taxonomy for the review of literature specifically in the field of Science Fiction Prototyping (SFP) and Foresight Innovation.
Ward, G., Jaddoa, A.
core +1 more source
FEBS Open Bio, EarlyView.Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page +4 more
wiley +1 more source
, 2017 Open innovation strategies have become commonplace in practice and as object of study. Although a lot of work has identified types of strategies and motives for employing them, relatively little is known about why and how exactly firms transition from a ...
Holgersson, Marcus,, van Santen, Sarah,
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