Results 131 to 140 of about 15,603,096 (267)
Information Technology Newsletter June 2005
University of Minnesota: Office of Information Technology. (2005). Information Technology Newsletter June 2005.
University of Minnesota: Office of Information Technology
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The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Information Technology Newsletter December 2004
University of Minnesota: Office of Information Technology. (2004). Information Technology Newsletter December 2004.
University of Minnesota: Office of Information Technology
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Information Technology Newsletter April 2005
University of Minnesota: Office of Information Technology. (2005). Information Technology Newsletter April 2005.
University of Minnesota: Office of Information Technology
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O padrão de deposição volumétrica é um parâmetro muito importante para a seleção da ponta de pulverização adequada para cada aplicação de agrotóxico. Assim, este trabalho teve como objetivo analisar a distribuição volumétrica de pontas de pulverização ...
João Paulo Arantes Rodrigues da Cunha
doaj
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Information Technology Newsletter September 2005
University of Minnesota: Office of Information Technology. (2005). Information Technology Newsletter September 2005.
University of Minnesota: Office of Information Technology
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Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Information Technology Newsletter November 2005
University of Minnesota: Office of Information Technology. (2005). Information Technology Newsletter November 2005.
University of Minnesota: Office of Information Technology
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