Results 141 to 150 of about 6,175,713 (309)
USING NON-BLASTING TECHNOLOGIES FOR DESTRUCTION OF HARD ROCK IN SURFACE MINING [PDF]
, 2018 Determination the effective application field of non-blasting technology and technologies for the hard rock preparation for excavation during surface ...
DREBENSTEDT, Carsten +2 more
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Domed Fresnel lens concentrator technology for space application [PDF]
Over the past three years, NASA Lewis and Entech, Inc. have been investigating the use of high efficiency refractive photovoltaic concentrators for use in space.
Oneill, Mark J. +1 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
A summary of the application of active controls technology in the ATT system studies [PDF]
The application of active controls technology to subsonic, long-range transport aircraft was investigated in three Advanced Transport Technology system studies.
Hood, R. V.
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Avionics systems integration technology [PDF]
A very dramatic and continuing explosion in digital electronics technology has been taking place in the last decade. The prudent and timely application of this technology will provide Army aviation the capability to prevail against a numerically superior
Stech, George, Williams, James R.
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Evaluation of low wing-loading fuel conservative, short-haul transports [PDF]
Fuel conservation that could be attained with two technology advancements, Q fan propulsion system and active control technology (ACT) was studied. Aircraft incorporating each technology were sized for a Federal Aviation Regulation (FAR) field length of ...
Pasley, L. H., Waldeck, T. A.
core +1 more source