Results 91 to 100 of about 40,939 (252)

H2S‐Releasing Aspirin Nanoparticles Alleviate Endometriosis and Associated Anxiety

Advanced Science, EarlyView.
Albumin nanoparticles loaded with an H2S‐releasing aspirin derivative (ACS14) hitchhiking neutrophils after intraperitoneal injection and preferentially accumulate in endometriosis lesions in mice. The treatment suppresses lesion growth by regulating PI3K/Akt and reduces inflammation by inhibiting NF‐κB.
Mengni Zhou, Renbin Dou, Rong Wu, Yunyu Xu, Ying Wang, Peng Wang, Jinfu Li, Pengcheng Lu, Yu Mao, Jieying Qian, Yunjiao Zhang, Jiqian Zhang, Shasha Zhu   +12 more
wiley   +1 more source

Transformation and Summation Formulas for Exton's Functions K11, K14 And K15

مجلّة جامعة عدن للعلوم الأساسيّة والتّطبيقيّة, 2020
The aim of the present paper is to establish some transformation formulas for Exton's quadruple hypergeometric functions K11, K14 and K15. Several summation formulas for K11, K14 and K15 are also derived as an applications of our main results with the ...
Ahmed Ali Atash, Hussein Saleh Bellehaj
doaj  

Multi‐Scale Mapping of Gene Expression from Whole‐slide Images for Identifying Phenotype‐Associated Subpopulations

Advanced Science, EarlyView.
BiSCALE: A pathology‐driven deep learning framework for multi‐scale gene expression prediction from whole‐slide images. It accurately infers bulk and near‐cellular spot‐level expression, links predictions to clinical phenotypes, identifies disease‐associated niches, and enables applications in risk stratification and cell‐identity annotation, providing
Hailong Zheng, Jiajing Xie, Luqi Wang, Hailong Xie, Tong Zhi, Yujia Guo, Bofeng Zhu, Dong Wang, Yu Chen   +8 more
wiley   +1 more source

Pancancer Fine‐Mapping of Mutational Intolerance Identifies CHEK1 as an Immunosuppressive Driver in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study identifies mutation‐intolerant genes (MIGs), which are mutationally constrained in tumors despite normal‐tissue variability. Using miDriver, the authors pinpoint MIGs essential for tumor‐intrinsic fitness and immune evasion. Focusing on CHEK1, they show it drives tumor fitness and sculpts an immunosuppressive niche via the MIF–CD74 axis ...
Tao Wang, Hongyu Zhao, Xiaojie Sun, Yuqi Ding, Zhipeng Zhu, Xiaotong Yu, Rongyi Zhu, Dan Wang, Kailong Li, Yang Liu, Li‐Bin Wang, Xiaolu Zhao, Baojun Suo, Hongsen Bi, Peipei Zhang, Tong Liu, Fengbiao Mao   +16 more
wiley   +1 more source

General integral formulas involving Hubert hypergeometric functions of two variables [PDF]

Mathematica Moravica, 2017
In this paper, we have established two general integral formulas involving Humbert hypergeometric functions of two variables ψ2 and 2. The results are obtained with the help of a generalization of classical Kummer's summation theorem on the sum of the ...
Atash Ali Ahmed, Bellehaj Saleh Hussein
doaj  

On the Generalized Confluent Hypergeometric Function and Its Application [PDF]

, 2006
2000 Mathematics Subject Classification: 26A33, 33C20This paper is devoted to further development of important case of Wright’s hypergeometric function and its applications to the generalization of Γ-, B-, ψ-, ζ-, Volterra ...
Virchenko, Nina
core  

Derivatives of continued fractions with applications to hypergeometric functions

Journal of Computational and Applied Mathematics, 1987
The purpose of the present paper is to illustrate the method on regular C-fraction expansions for certain hypergeometric functions. The emphasis is on developing the formulas needed. Numerical examples are indicated in some special cases.
openaire   +1 more source

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

Applications of Volterra's theory of composition to hypergeometric functions

, 2018
The main results of this thesis are the generalizations of previous known results given by Hadamard (6), and Thielman (12) on integral addition theorems of Bessel functions, namely Theorems 5.8 and 5.9. Also an integral addition theorem, Theorem 5.10, for Laguerre polynomials is obtained;The methods used are based on the isomorphism which exists ...
openaire   +3 more sources

Metarhizium anisopliae Mitigates the Phytotoxicity of Lead and Nanoplastics on Rice by Modifying Physiological, Transcriptomic, Metabolomic Activities, and Soil Microbiome

Advanced Science, EarlyView.
Metarhizium anisopliae alleviates the phytotoxic effects of polyethylene nanoplastics (NP) and lead (Pb) in rice by decreasing Pb uptake, restoring antioxidant and hormonal equilibrium, and promoting growth. Additionally, the fungus modifies the rhizosphere microbiota, enhancing both contaminant tolerance and plant growth, thereby effectively ...
Jing Peng, Qi Yan, Muhammad Umair Hassan, Muhammad Imran, Fasih Ullah Haider, Jianfeng Liang, Xingmin Wang, Shaukat Ali   +7 more
wiley   +1 more source