Results 111 to 120 of about 40,939 (252)

Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy

Advanced Science, EarlyView.
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao, Zihan Deng, Yufei Liu, Li Liu, Deqiang Deng, Muyang Yang, Yuanyuan Geng, Yao Sun, Beilei Yue, Jonathan F. Lovell, Yushuai Liu, Lisen Lu, Honglin Jin   +12 more
wiley   +1 more source

Operational Methods in the Study of Sobolev-Jacobi Polynomials

Mathematics, 2019
Inspired by ideas from umbral calculus and based on the two types of integrals occurring in the defining equations for the gamma and the reciprocal gamma functions, respectively, we develop a multi-variate version of umbral calculus and of the so-called ...
Nicolas Behr, Giuseppe Dattoli, Gérard H. E. Duchamp, Silvia Licciardi, Karol A. Penson   +4 more
doaj   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

On a class of generalized analytic functions

Le Matematiche, 2012
This paper deals with a new generalization of analytical functions.The p-wave functions are introduced and studied. We consider their theoretical aspect and applications. Some integral representations of x^k y^l -wave functions (k, l − const.
Shyam L. Kalla, Nina Virchenko, Iryna Alexsandrovich   +2 more
doaj  

A Class of Extended Hypergeometric Functions and Its Applications

, 2013
Recently, there emerges different versions of beta function and hypergeometric functions containing extra parameters. Gaining enlightenment from these ideas, we will first introduce a new extension of generalized hypergeometric function and then put forward some fundamental results in the paper. Next, we will derive some properties of certain functions
openaire   +2 more sources

A new class of meromorphically multivalent functions with applications to generalized hypergeometric functions

Mathematical and Computer Modelling, 2006
In this paper the authors define a class of functions \(f(z)\) that are meromorphic, normalized, analytic and \(p\)-valent in the punctured unit disc \(U^*\) and satisfy the subordination \[ \gamma\frac{(f*g)^{(m)}(z)}{(f*h)^{(m)}(z)} \prec \gamma -\frac{p(A-B)z}{1+Bz} \quad (z\in U^*), \] where \(\gamma>0,\) \(0\leq ...
Raina, R. K., Srivastava, H. M.
openaire   +1 more source

PVT1 lincRNA signals an androgen‐dependent transcriptional activation program of oncogenes in prostate cancer cells

International Journal of Cancer, EarlyView.
What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho, Fabio Nunes de Mello, Ana Carolina Tahira, Gabriel Nakanishi Fortes, Agatha Fischer‐Carvalho, Pedro Jardim Poli, Murilo Sena Amaral, Sergio Verjovski‐Almeida   +7 more
wiley   +1 more source

Alternative Price Dynamics and Valuation of Flexible Strategies

International Journal of Finance &Economics, EarlyView.
ABSTRACT In this article, we study the optimal operational strategy of production projects. We investigate different underlying price models and determine the optimal barriers of transition to suspension, recovery, or irreversible abandonment of productive activity.
Cristina Bertolosi, Gianluca Fusai, Ioannis Kyriakou   +2 more
wiley   +1 more source

Monocytes with trained immunity–like signatures are associated with acute anterior uveitis in ankylosing spondylitis

Interdisciplinary Medicine, EarlyView.
In ankylosing spondylitis‐acute anterior uveitis (AS‐AAU), trained immunity monocytes (Mono‐TI) differentiate into macrophages in the eye, retaining trained immunity features. Mono‐TI cells secrete pro‐inflammatory cytokines and chemokines, including IL‐1β, TNF‐α, and CCL3.
Yimeng Sun, Lu Zhang, Xinyu Yao, Yunfei Liu, Xin Li, Feng Wen, Yong Dai, Ye Dai, Ziyu Du, Dijie Qiao, Ziwei Meng, Cong Hu, Chun Yan, Wei Chi   +13 more
wiley   +1 more source

A highly accurate numerical method for solving boundary value problem of generalized Bagley‐Torvik equation

Mathematical Methods in the Applied Sciences, EarlyView.
A highly accurate numerical method is given for the solution of boundary value problem of generalized Bagley‐Torvik (BgT) equation with Caputo derivative of order 0<β<2$$ 0<\beta <2 $$ by using the collocation‐shooting method (C‐SM). The collocation solution is constructed in the space Sm+1(1)$$ {S}_{m+1}^{(1)} $$ as piecewise polynomials of degree at ...
Suzan Cival Buranay, Mtema James Chin, Nazim I. Mahmudov   +2 more
wiley   +1 more source