Results 121 to 130 of about 782,440 (256)

Bioinformatics Applications in Life Sciences and Technologies. [PDF]

Biomed Res Int, 2016
Sousa SA, Leitão JH, Martins RC, Sanches JM, Suri JS, Giorgetti A.   +5 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Diazirines Beyond Photoaffinity Labeling: A Comprehensive Overview of Applications in Biological Sciences, Materials Chemistry, and NMR-Spectroscopy. [PDF]

Angew Chem Int Ed Engl
Schnalzer D, Savic V, Cziegler C, Schnürch M, Mihovilovic MD.   +4 more
europepmc   +1 more source

Cerenkov luminescence imaging: physics principles and potential applications in biomedical sciences. [PDF]

EJNMMI Phys, 2017
Ciarrocchi E, Belcari N.
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Fast Small-Angle X-Ray Scattering Tensor Tomography: An Outlook into Future Applications in Life Sciences. [PDF]

Small Methods
Appel C, Schmeltz M, Rodriguez-Fernandez I, Anschuetz L, Nielsen LC, Panepucci E, Marijolovic T, Wakonig K, Ivanovic A, Bonnin A, Leonarski F, Wojdyla J, Tomizaki T, Guizar-Sicairos M, Smith K, Beale JH, Glettig W, McAuley KE, Bunk O, Wang M, Liebi M.   +20 more
europepmc   +1 more source

Dynamic light scattering: a practical guide and applications in biomedical sciences. [PDF]

Biophys Rev, 2016
Stetefeld J, McKenna SA, Patel TR.
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

A Comprehensive Review of Niobium Nanoparticles: Synthesis, Characterization, Applications in Health Sciences, and Future Challenges. [PDF]

Nanomaterials (Basel)
Khalid MU, Rudokaite A, da Silva AMH, Kirsnyte-Snioke M, Stirke A, Melo WCMA.   +5 more
europepmc   +1 more source

The Application of Science to Medicine

American Journal of Pharmaceutical Education, 1951
openaire   +1 more source