Results 81 to 90 of about 351,690 (298)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The Effect of Educational Drama on the Collection of Arabic Grammar Middle school students
الأستاذ, 2018 The aim of this research is to find out the effect of the educational drama method in the achievement of middle school students. A sample of 60 students from the second intermediate class was selected.
Dr. Rahim Ali Saleh
doaj +1 more source
Acting on behalf of the concept [PDF]
, 2003 This paper discusses how drama process and techniques are providing alternative approaches to product concept generation. An investigation that used drama techniques for concept generation sessions observed that there appears to be an implicit response ...
Hilton, Kevin
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Przestrzenie Teorii, 2007 The book by Patrice Pavis Le theatre contemporain. Analyse des textes, de Sarraute k Vinaver comprises the collection of essays on the contemporary French drama.
Beata Popczyk-Szczęsna
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The Role of Drama in Task-based Learning: Agency, Identity and Autonomy
SCENARIO: Journal for Performative Teaching, Learning, Research, 2012 Drama is a genre which connects the public and private, the rehearsed and the spontaneous, the self and the other. These intriguing relationships may be examined, from an applied linguistic perspective, through the concepts of agency, autonomy and ...
Lorna Carson
doaj +1 more source
Preaching to Episodic Ears: Practicing a Dramaturgical Homiletic
, 2019 This article is a critical attempt to develop a homiletic methodology for preaching to the episodic self of the 21st century. The British philosopher Galen Strawson contends that postmodern people today do not regard themselves as living out their lives ...
Yang, Sunggu
core
The dialogic aspects of Mantle of the Expert pedagogy used to teach devising at NCEA Level 2 in a Year 12 classroom "I don't think it's about credits- definitely not about credits" [PDF]
, 2013 This inquiry sets out to gather and consider student and teacher perceptions about the affordances and constraints of using Mantle of the Expert pedagogy, to support teaching and learning, through the process of devising drama at NCEA Level in a Year 12 ...
Stoate, Gaenor Anne
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source