Results 51 to 60 of about 15,813,200 (328)
Statistical microdamage mechanics and damage field evolution
Discussed are the underlying background of statistical microdamage mechanics, the fundamental partial differential equation of evolution of microdamage number density, two basic solutions, and the saturation of microdamage number density evolution ...
Bai, YL (reprint author), Chinese Acad Sci, Inst Mech, LNM, State Key Lab Nonlinear Mech, Beijing 100080, Peoples R China. +8 more
core +2 more sources
Fatigue database of complex metallic alloys
The past few decades have witnessed rapid progresses in the research and development of complex metallic alloys such as metallic glasses and multi-principal element alloys, which offer new solutions to tackle engineering problems of materials such as the
Zian Zhang, Haoxuan Tang, Zhiping Xu
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Design Principles for Deployable Fibers Inspired by Hagfish Defense
Hagfish produce extraordinary slime as a defense mechanism, releasing exudate from glands that rapidly form a fibrous, soft, ultra‐dilute, water‐capturing network upon contact with seawater (up to 10 000 times its original volume). The gland thread cell (
Mohammad Tanver Hossain +8 more
doaj +1 more source
An Analytical Solution for Static Problems of Cantilever Curved Beams with Variable Cross Sections
This paper gives an analytical method to obtain the deformation of a cantilever curved beam. The curved beam considered has circular centre line and the thickness of the cross section in radial direction depends on the circumferential coordinate.
István Ecsedi +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Comparison of Flow field in the proximity of A Single Planar & Wrap-around Fin
This paper analyses the results of the computational analysis between a single planar and a wrap-around fin mounted on a semi-cylindrical body. A free-stream Computational Fluid Dynamics (CFD) model was simulated for both cases in the Mach 0.4-3.0M range
Nayhel Sharma +4 more
doaj +1 more source
Torsion of Truncated Hollow Spherical Elastic Body
This paper deals with the torsion of a body of rotation whose shape is a truncated hollow sphere. The material of the truncated hollow sphere is isotropic, homogeneous and linearly elastic.
István Ecsedi +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

