Results 61 to 70 of about 6,104,454 (322)

Imaging arbitrary incoherent source distributions with near quantum-limited resolution

open access: yesScientific Reports, 2022
We demonstrate an approach to obtaining near quantum-limited far-field imaging resolution of incoherent sources with arbitrary distributions. Our method assumes no prior knowledge of the source distribution, but rather uses an adaptive approach to ...
Erik F. Matlin, Lucas J. Zipp
doaj   +1 more source

A Snapshot Infrared Imaging Fourier Transform Spectrometer for Dynamic Target Detection

open access: yesRemote Sensing, 2022
Infrared imaging spectrometry is utilized to detect and identify targets by collecting spectral images. In some cases, the infrared spectral images of dynamic targets need to be detected accurately, such as during remote sensing target tracking and ...
Yupeng Chen   +8 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

A Global Decoupling Control Algorithm for LC-DM Adaptive Optics System

open access: yesIEEE Access, 2021
The liquid crystal (LC) and deformable mirror (DM) cascaded adaptive optics (AO) system can be used to effectively extend the imaging waveband of a large aperture telescope from the infrared to the visible waveband. However, to maintain the effectiveness
Yukun Wang   +4 more
doaj   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Light Scattering of optical Components and their Imperfections: Measurement, Modelling, and System Analysis [PDF]

open access: yesEPJ Web of Conferences
Light scattering in optical systems is caused by various imperfections such as surface roughness, bulk inhomogeneity, contamination, and ghost light beam paths.
Herffurth Tobias   +3 more
doaj   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

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