Results 71 to 80 of about 3,680,137 (291)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Report of onsite training fish handling onboard fishing vessels [PDF]

open access: yes, 2022
This report is a part of onsite training on fish handling onboard fishing vessels for fishers, fishery officers, key stakeholders, and students that conducted 1-day training on 8 July 2022 at 09:00–15:00 hrs. at the Prince of Songkhla University, Pattani

core  

Towards a Broader Agenda for Training in Critical Appraisal

open access: yesJournal of the Royal College of Physicians of London, 1999
Much progress has been made in recent years towards an evidence-based approach to health care, i.e. the routine framing of an explicit decision sequence in the clinical encounter, the systematic search for published evidence, and the appraisal of relevant research articles. We argue that this is a commendable but limited milestone, and that training in
T, Greenhalgh, A, Herxheimer
openaire   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Appraisal: The Deanery, Bryn Mawr, PA (1949) [PDF]

open access: yes, 1949
An appraisal of the furniture and furnishings of the Deanery, performed by The Manufacturers\u27 Appraisal Company in 1949.https://repository.brynmawr.edu/bmc_books/1018/thumbnail ...
The Manufacturers\u27 Appraisal Company
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

The Impact of Human Resources Management Strategies on Improving Job Performance: A Field Study at Ahmed Medeghri Hospital in Saida

open access: yesAkofena
: This study aimed to measure the impact of human resource management strategies-specifically recruitment strategy, training and development strategy, performance appraisal strategy, and motivation strategy—on improving employee performance at Ahmed ...
Abdelkader TALHA, Abdelkader MAKHLOUF, Kada YAZID & Abdelkrim MERAHI
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Annual report (Online); Other title: Title from file name: OPOTA annual report; Other title: ... Ohio Peace Officer Training Commission and Academy fiscal year annual report; Other title: Fiscal year annual report

open access: yes
Annual; Report for 2008 covers the calendar year; report for 2009 not published; report for 2010- covers the state fiscal year (July-June)
Ohio Peace Officer Training Commission.
core   +1 more source

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