Results 51 to 60 of about 165,322 (267)
Analysis of the relevance of antibiotic therapy and the experience of prescribers in the pediatric department at Bouaké University Hospital (Côte d'Ivoire) [PDF]
Hospital PharmacologyIntroduction: Infectious diseases, particularly among pediatric populations, represent a significant global health problems. Rational antibiotic use is paramount for achieving optimal patient outcomes, but prescribing antibiotics in pediatric settings is
Balayssac Eric Joseph +4 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The FIT FIRST 10 dose-response study: evaluation of implementation outcomes
Frontiers in Sports and Active LivingIntroductionIncreasing physical activity (PA) levels among children is critical to mitigate health risks associated with physical inactivity. Schools have been highlighted as ideal setting for promoting PA.
Sofie Koch +15 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Antibiotics, 2020 Surgical site infections (SSIs) are the most common healthcare-associated infections. The appropriate use of Surgical Antibiotic Prophylaxis (SAP) is a key component to reduce SSIs, while its inappropriate application is a major cause of some emerging ...
Beatrice Tiri +14 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Ideology, Access, and Status: Spanish-English Bilinguals in the Foreign-Language Classroom
Bellaterra Journal of Teaching & Learning Language & Literature, 2016 Spanish language teaching in US higher education is today generally divided between ‘foreign language’ courses for novice learners and ‘heritage language’ courses for Hispanic/Latinx students with some knowledge of the language.
Michael E. Rolland
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Evaluating the appropriateness of chemotherapy in a low‐resource cancer centre in sub‐Saharan Africa
Cancer Medicine, 2020 Background To evaluate the appropriateness of chemotherapy use at the Oncology Department of the Bugando Medical Centre of Mwanza, Tanzania. Methods The study was an observational prevalence‐based study designed to evaluate a single‐chemotherapy cycle ...
Patrizia Serra +9 more
doaj +1 more source