Results 191 to 200 of about 428 (244)

A dynamic examination of the digital circuit implementing the Fitzhugh-Nagumo neuron model with emphasis on low power consumption and high precision. [PDF]

PLoS One
Nadiri Andabili M, Nazari S, Moosazadeh T.   +2 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Computing-in-memory architecture for Kolmogorov-Arnold networks based on tunable Gaussian-like memory cells. [PDF]

Nat Commun
Wen Z, Zhang Q, Chen J, Yang T, Yang F, Wang X, Liu Q, Luo X, Lin P, Deng LJ, Liu F.   +10 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Spintronic Bayesian Hardware Driven by Stochastic Magnetic Domain Wall Dynamics. [PDF]

Adv Sci (Weinh)
Wang T, Dai B, Xu S, Wong K, Li Y, Cheng Y, Shu Q, He H, Huang P, Huang H, Zhang X, Wang KL.   +11 more
europepmc   +1 more source

Comparison metrics and power trade-offs for BCI motor decoding circuit design. [PDF]

Front Hum Neurosci
Saad J, Evans A, Jaoui I, Roux-Sibillon V, Hardy E, Anghel L.   +5 more
europepmc   +1 more source

Design of Low-Cost and Highly Energy-Efficient Convolutional Neural Networks Based on Deterministic Encoding. [PDF]

Sensors (Basel)
Tong T, He Q, Nie X, Zhao Y.
europepmc   +1 more source

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Probabilistic Error Modeling for Approximate Adders

IEEE Transactions on Computers, 2017
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jörg Henkel, Muhammad Shafique, Rehan Hafiz   +2 more
exaly   +4 more sources

Single Exact Single Approximate Adders and Single Exact Dual Approximate Adders

IEEE Transactions on Very Large Scale Integration (VLSI) Systems, 2023
Joycee Mekie, Chandan Kumar Jha
exaly   +2 more sources

Analysis of various Approximate adders in Ripple Carry Adder design.

2023 4th IEEE Global Conference for Advancement in Technology (GCAT), 2023
R.V Nithyashree, S Afreen, Shashidhar Tantry   +2 more
exaly   +2 more sources