Results 41 to 50 of about 22,837 (216)

Automated generation of heuristics for biological sequence comparison

open access: yesBMC Bioinformatics, 2005
Background Exhaustive methods of sequence alignment are accurate but slow, whereas heuristic approaches run quickly, but their complexity makes them more difficult to implement.
Birney Ewan, Slater Guy
doaj   +1 more source

OPTIMAL CONTROL FOR A CONTROLLED ILL-POSED WAVE EQUATION WITHOUT REQUIRING THE SLATER HYPOTHESIS

open access: yesUral Mathematical Journal, 2020
In this paper, we investigate the problem of optimal control for an ill-posed wave equation without using the extra hypothesis of Slater i.e. the set of admissible controls has a non-empty interior. Firstly, by a controllability approach, we make the ill-
Abdelhak Hafdallah
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A relationship between the modified Euler method and e

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1985
Approximating solutions to the differential equation dy/dx=f(x,y) where f(x,y)=y by a generalization of the modified Euler method yields a sequence of approximates that converge to e. Bounds on the rapidity of convergence are determined, with the fastest
Richard B. Darst, Thomas P. Dence
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Pseudo Random Number Generation through Reinforcement Learning and Recurrent Neural Networks

open access: yesAlgorithms, 2020
A Pseudo-Random Number Generator (PRNG) is any algorithm generating a sequence of numbers approximating properties of random numbers. These numbers are widely employed in mid-level cryptography and in software applications.
Luca Pasqualini, Maurizio Parton
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

APPROXIMATING SOLUTIONS FOR A CLASS OF STOCHASTIC FRACTIONAL LINEAR QUADRATIC OPTIMAL CONTROL PROBLEMS [PDF]

open access: yesAnalele Universităţii "Constantin Brâncuşi" din Târgu Jiu: Seria Inginerie, 2018
In this paper we consider a linear quadratic control problem for a class of discretetime fractional order systems with multiplicative noise and we find lower bounds of the optimal cost and approximating solutions for the optimal control law.
Viorica Mariela Ungureanu
doaj  

Iterative Algorithms for Split Common Fixed Point Problem Involved in Pseudo-Contractive Operators without Lipschitz Assumption

open access: yesMathematics, 2019
Two iterative algorithms are suggested for approximating a solution of the split common fixed point problem involved in pseudo-contractive operators without Lipschitz assumption.
Jinzuo Chen   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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