Results 91 to 100 of about 1,007,914 (329)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A Novel Method of Offset Approximation along the Normal Direction with High Precision

Mathematical and Computational Applications, 2017
A new algorithm is proposed for polynomial or rational approximation of the planar offset curve. The best rational Chebyshev approximation could be regarded as a kind of geometric approximation along the fixed direction.
Hongyan Zhao, Lian Zhou
doaj   +1 more source

An efficient 3-approximation algorithm for the Steiner tree problem with the minimum number of Steiner points and bounded edge length. [PDF]

PLoS One, 2023
Shin D, Choi S.
europepmc   +1 more source

A Novel Genetic Algorithm using Helper Objectives for the 0-1 Knapsack Problem [PDF]

, 2014
The 0-1 knapsack problem is a well-known combinatorial optimisation problem. Approximation algorithms have been designed for solving it and they return provably good solutions within polynomial time.
Dong, Hongbin, He, Feidun, He, Jun
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

A duality based 2-approximation algorithm for maximum agreement forest. [PDF]

Math Program, 2023
Olver N, Schalekamp F, van der Ster S, Stougie L, van Zuylen A.   +4 more
europepmc   +1 more source

Rapid near-optimal VQ design with a deterministic data net [PDF]

, 2005
We present a new algorithm for fixed-rate vector quantizer (VQ) design with deterministic data net. The algorithm also performs efficient VQ design for simply characterized continuous distributions. The algorithm also serves as an approximation algorithm
Effros, Michelle, Schulman, Leonard J.
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

A new 1.375-approximation algorithm for sorting by transpositions. [PDF]

Algorithms Mol Biol, 2022
Silva LAG, Kowada LAB, Rocco NR, Walter MEMT.   +3 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source