Results 51 to 60 of about 223,993 (286)

Approximation of conic sections by weighted Lupaş post-quantum Bézier curves

Demonstratio Mathematica, 2022
This paper deals with weighted Lupaş post-quantum Bernstein blending functions and Bézier curves constructed with the help of bases via (p,q)\left(p,q)-integers. These blending functions form normalized totally positive bases.
Khan Asif, Iliyas Mohammad, Khan Khalid, Mursaleen Mohammad   +3 more
doaj   +1 more source

Towards a More General Type of Univariate Constrained Interpolation With Fractal Splines

, 2015
Recently, in [Electronic Transaction on Numerical Analysis, 41 (2014), pp. 420-442] authors introduced a new class of rational cubic fractal interpolation functions with linear denominators via fractal perturbation of traditional nonrecursive rational ...
Chand, A. K. B., Reddy, K. M., Viswanathan, P.   +2 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

General results on the convergence of multipoint Hermite-Padé approximants of Nikishin systems [PDF]

, 2007
19 pages, no figures.-- MSC1991 codes: Primary 30E10, 42C05.MR#: MR2263738 (2007g:42041)Zbl#: Zbl 1105.30024We consider simultaneous approximation of Nikishin systems of functions by means of rational vector functions which are constructed interpolating ...
Fidalgo Prieto, Ulises, López Lagomasino, Guillermo   +1 more
core   +3 more sources

On the Domain of Analytical Continuation of the Ratios of Generalized Hypergeometric Functions ₃F₂

Axioms
The paper considers the problem of the analytical extension of the ratios of generalized hypergeometric functions F23 A new domain of analytic continuation for these ratios under certain conditions to parameters is established.
Roman Dmytryshyn, Marta Dmytryshyn, Sofiia Hladun   +2 more
doaj   +1 more source

Analytic continuation with Pad\'e decomposition

, 2017
The ill-posed analytic continuation problem for Green's functions or self-energies can be done using the Pad\'e rational polynomial approximation. However, to extract accurate results from this approximation, high precision input data of the Matsubara ...
Han, Xing-Jie, Huang, Rui-Zhen, Liao, Hai-Jun, Meng, Zi Yang, Xiang, Tao, Xie, Hai-Dong   +5 more
core   +1 more source