Results 81 to 90 of about 7,666,446 (331)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Approximation by Jakimovski–Leviatan-beta operators in weighted space

open access: yesAdvances in Difference Equations, 2020
The main purpose of this article is to introduce a more generalized version of Jakimovski–Leviatan-beta operators through the Appell polynomials. We present some uniform convergence results of these operators via Korovkin’s theorem and obtain the rate of
M. Nasiruzzaman, M. Mursaleen
doaj   +1 more source

Lagrange approximation in Banach spaces [PDF]

open access: yesCzechoslovak Mathematical Journal, 2015
Using an integral representation formula for holomorphic functions on Banach spaces combined with Lagrange interpolation of the exponential function \(e^z\) in the complex plane, the authors define Lagrange interpolating polynomials for representable functions defined on a Banach space \(E\).
Nilsson, Lisa   +2 more
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Approximate property of a functional equation with a general involution

open access: yesDemonstratio Mathematica, 2018
In this paper, we prove the Hyers-Ulam stability of the functional equation f(x + y, z + w) + f(x + σ(y),z + τ(w)) = 2f(x, z) + 2f(y, w), where σ, τ are involutions.
Park Won-Gil, Bae Jae-Hyeong
doaj   +1 more source

Local Approximation Spaces

open access: yesZeitschrift für Analysis und ihre Anwendungen, 1989
The paper deals with characterizations of spaces F^s_{pq} and B^s_{pq} on \mathbb R^n, \mathbb R^n_+
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Approximation in trigonometric Lipschitz spaces

open access: yes, 2021
The approximation by generalized trigonometric polynomials for Lipschitz defined functions in certain groups depends on some properties of the group defined metric. Metrics which allow this approximation are called Lipschitz compatible. In this work we give for certain class of groups, conditions under which Lipschitz compatible metrics are boundedly ...
Bernabé Loranca, María Beatriz   +3 more
openaire   +3 more sources

Linear programming error bounds for random walks in the quarter-plane [PDF]

open access: yes, 2012
We consider approximation of the performance of random walks in the quarter-plane. The approximation is in terms of a random walk with a product-form stationary distribution, which is obtained by perturbing the transition probabilities along the ...
Boucherie, Richard J.   +2 more
core   +3 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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